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The map label for this gene is dadA

Identifier: 218709126

GI number: 218709126

Start: 1199679

End: 1200932

Strand: Direct

Name: dadA

Synonym: VS_1133

Alternate gene names: 218709126

Gene position: 1199679-1200932 (Clockwise)

Preceding gene: 218709125

Following gene: 218709131

Centisome position: 36.36

GC content: 45.85

Gene sequence:

>1254_bases
ATGGAAGTTATTGTAATTGGTAGCGGTGTTATTGGGTTAACCAGTGCTTGGTACCTTGCGAAAGAAGGTCATACAGTGAC
GGTTATTGATCGTCAAGATAGCAGTGGCAAGGAAACCAGCTTTGCGAATGCAGGGCAAATTTCTTACGGATATTCTTCAC
CATGGGCGGCACCGGGGATTCCGTTGAAAGCAATGAAATGGCTTACCCAAGAGCATGCGCCTCTAAAAGTGAAGCCTTCA
CTTTCTCCTGAATTAGTTGCTTGGGCGACTAAGATGTTGGCCAACTGTAATGAAGCCAAGTACGCCATGAATAAGTCACG
CATGTTAAGAGTGGCAAACTTCAGTCGAGAGTGTCTTACTCATCTAAGAACCAGTGAAGATTTAGCTTATGAGGGCAGGC
AGAAAGGCACCTTGCAAGTATTCAGAAGCGAGAAGCAACTCGATGCTATTCAGCAGGATATGAAGCTATTAACAGAGAGT
GGGATCGAACACTCGCTGTTTGATGTTGACCAGTGTCTGTCAGTGGAGTCGGGTTTAGCGGACGTCAAAGACAAGCTGGT
GGGCGGCTTATACTTACCTCATGATGAAACCGGTGATTGCCATCAGTTCTGTTTAACCTTGACTGAGAAAGCCAAGCAAC
TCGGTGTTAGGTTCGTGTTTGATACTGAAGTGGTAAGTTTGAATCATCAGAATCGAGCCATTGAGACTATTACAACGACT
CAAGGCGAGTTTAAAGCGGATGCTTACGTGGTCGCGTCAGGAAGCTATTCTCGAGAACTATTAAAGCAAGTCGACTTGTC
TATACCGGTTTACCCAGTCAAAGGATATTCACTAACATTGCCTATCGTGAATGTAGATAAGTCACCGACTTCGACTGTTA
TGGATGAAACCTACAAGGTCGCGATGACGCGATTTGATGATCGTATTCGTATCGCGGGTACGGCAGAACTCGCTGGTTTT
GACTACCTAATCCCAGAAAAACGTAAAGCCACGATTGATATGGTGATAAAAGATCTTTTCCCACAAGCGGGGGACTTTTC
TAAGGCTGAATACTGGACTGGGCTAAGACCAATGACGCCAGATGGCACGCCTATCATCGGCAAGACGCCTATCAAGAACC
TATTTACCAATACGGGACACGGAACCTTGGGTTGGACGATGGCGTGTGGCTCAGGAAAGATCCTAGCAAGCGTGGTCAGT
GGCTCTGCCAGTGATATTAAATCTGATGACTTAAGTATCCATCGTTATTTGTAG

Upstream 100 bases:

>100_bases
CAACATGCGCGGAATAAGTTACAAATTATTAACGAAACGAGTTTTAGACTGACAGCTGTGTTCGACAGGTTTTGGCTTTG
TCGGGCATTAGGGGAAGAGA

Downstream 100 bases:

>100_bases
CGGCATGACACCGTGTTAACTAAAGTCACCCCATTCTTAAACTGTAGAATGGGGTTATGGGTTCTCAAGGAGAAGATTAT
CTGGTGGTTGTTTCTAGTAC

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MEVIVIGSGVIGLTSAWYLAKEGHTVTVIDRQDSSGKETSFANAGQISYGYSSPWAAPGIPLKAMKWLTQEHAPLKVKPS
LSPELVAWATKMLANCNEAKYAMNKSRMLRVANFSRECLTHLRTSEDLAYEGRQKGTLQVFRSEKQLDAIQQDMKLLTES
GIEHSLFDVDQCLSVESGLADVKDKLVGGLYLPHDETGDCHQFCLTLTEKAKQLGVRFVFDTEVVSLNHQNRAIETITTT
QGEFKADAYVVASGSYSRELLKQVDLSIPVYPVKGYSLTLPIVNVDKSPTSTVMDETYKVAMTRFDDRIRIAGTAELAGF
DYLIPEKRKATIDMVIKDLFPQAGDFSKAEYWTGLRPMTPDGTPIIGKTPIKNLFTNTGHGTLGWTMACGSGKILASVVS
GSASDIKSDDLSIHRYL

Sequences:

>Translated_417_residues
MEVIVIGSGVIGLTSAWYLAKEGHTVTVIDRQDSSGKETSFANAGQISYGYSSPWAAPGIPLKAMKWLTQEHAPLKVKPS
LSPELVAWATKMLANCNEAKYAMNKSRMLRVANFSRECLTHLRTSEDLAYEGRQKGTLQVFRSEKQLDAIQQDMKLLTES
GIEHSLFDVDQCLSVESGLADVKDKLVGGLYLPHDETGDCHQFCLTLTEKAKQLGVRFVFDTEVVSLNHQNRAIETITTT
QGEFKADAYVVASGSYSRELLKQVDLSIPVYPVKGYSLTLPIVNVDKSPTSTVMDETYKVAMTRFDDRIRIAGTAELAGF
DYLIPEKRKATIDMVIKDLFPQAGDFSKAEYWTGLRPMTPDGTPIIGKTPIKNLFTNTGHGTLGWTMACGSGKILASVVS
GSASDIKSDDLSIHRYL
>Mature_417_residues
MEVIVIGSGVIGLTSAWYLAKEGHTVTVIDRQDSSGKETSFANAGQISYGYSSPWAAPGIPLKAMKWLTQEHAPLKVKPS
LSPELVAWATKMLANCNEAKYAMNKSRMLRVANFSRECLTHLRTSEDLAYEGRQKGTLQVFRSEKQLDAIQQDMKLLTES
GIEHSLFDVDQCLSVESGLADVKDKLVGGLYLPHDETGDCHQFCLTLTEKAKQLGVRFVFDTEVVSLNHQNRAIETITTT
QGEFKADAYVVASGSYSRELLKQVDLSIPVYPVKGYSLTLPIVNVDKSPTSTVMDETYKVAMTRFDDRIRIAGTAELAGF
DYLIPEKRKATIDMVIKDLFPQAGDFSKAEYWTGLRPMTPDGTPIIGKTPIKNLFTNTGHGTLGWTMACGSGKILASVVS
GSASDIKSDDLSIHRYL

Specific function: Oxidative deamination of D-amino acids

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787438, Length=416, Percent_Identity=51.6826923076923, Blast_Score=466, Evalue=1e-132,
Organism=Drosophila melanogaster, GI28571104, Length=351, Percent_Identity=23.3618233618234, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DADA_VIBSL (B7VMK8)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416747.1
- GeneID:   7160718
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_1133
- HOGENOM:   HBG729204
- OMA:   WQMLQNC
- ProtClustDB:   PRK00711
- HAMAP:   MF_01202
- InterPro:   IPR023080
- InterPro:   IPR006076

Pfam domain/function: PF01266 DAO

EC number: =1.4.99.1

Molecular weight: Translated: 45866; Mature: 45866

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIVIGSGVIGLTSAWYLAKEGHTVTVIDRQDSSGKETSFANAGQISYGYSSPWAAPGI
CEEEEEECCHHHHHHHEEEEECCCEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCC
PLKAMKWLTQEHAPLKVKPSLSPELVAWATKMLANCNEAKYAMNKSRMLRVANFSRECLT
CHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHCHHHEEEHHHHHHHHHH
HLRTSEDLAYEGRQKGTLQVFRSEKQLDAIQQDMKLLTESGIEHSLFDVDQCLSVESGLA
HHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHH
DVKDKLVGGLYLPHDETGDCHQFCLTLTEKAKQLGVRFVFDTEVVSLNHQNRAIETITTT
HHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECEEEEECCCCCEEEEEEEC
QGEFKADAYVVASGSYSRELLKQVDLSIPVYPVKGYSLTLPIVNVDKSPTSTVMDETYKV
CCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHHHHHHH
AMTRFDDRIRIAGTAELAGFDYLIPEKRKATIDMVIKDLFPQAGDFSKAEYWTGLRPMTP
HHHHCCCEEEEEEEHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
DGTPIIGKTPIKNLFTNTGHGTLGWTMACGSGKILASVVSGSASDIKSDDLSIHRYL
CCCEECCCCCHHHHHCCCCCCCEEEEEECCCCCEEHHHHCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MEVIVIGSGVIGLTSAWYLAKEGHTVTVIDRQDSSGKETSFANAGQISYGYSSPWAAPGI
CEEEEEECCHHHHHHHEEEEECCCEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCC
PLKAMKWLTQEHAPLKVKPSLSPELVAWATKMLANCNEAKYAMNKSRMLRVANFSRECLT
CHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHCHHHEEEHHHHHHHHHH
HLRTSEDLAYEGRQKGTLQVFRSEKQLDAIQQDMKLLTESGIEHSLFDVDQCLSVESGLA
HHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHH
DVKDKLVGGLYLPHDETGDCHQFCLTLTEKAKQLGVRFVFDTEVVSLNHQNRAIETITTT
HHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECEEEEECCCCCEEEEEEEC
QGEFKADAYVVASGSYSRELLKQVDLSIPVYPVKGYSLTLPIVNVDKSPTSTVMDETYKV
CCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHHHHHHH
AMTRFDDRIRIAGTAELAGFDYLIPEKRKATIDMVIKDLFPQAGDFSKAEYWTGLRPMTP
HHHHCCCEEEEEEEHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
DGTPIIGKTPIKNLFTNTGHGTLGWTMACGSGKILASVVSGSASDIKSDDLSIHRYL
CCCEECCCCCHHHHHCCCCCCCEEEEEECCCCCEEHHHHCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA