Click here to switch to the map view.

The map label for this gene is viuG [H]

Identifier: 218709119

GI number: 218709119

Start: 1190191

End: 1191252

Strand: Direct

Name: viuG [H]

Synonym: VS_1125

Alternate gene names: 218709119

Gene position: 1190191-1191252 (Clockwise)

Preceding gene: 218709118

Following gene: 218709120

Centisome position: 36.07

GC content: 46.42

Gene sequence:

>1062_bases
ATGATGATTGAGCCTTACACTCTTCAACATTCTGGCTCGGGAAGTGTTGTACGCTTCGGTCAGTTTTCTTTCTGTTATCA
ACCGTCTCATATACTTGTCGCTTTGATTTTGTTGATATCAGTTTGCGCTATTGCAACTTATTCCATGACATTGGGTAAGT
TTAATATCTCGTTGCCTCAAGTGGCCGATATCACTCTTGGGGTTGGAGAGGGGGGCGTAAAAGAGCGAATAATTCTTAAC
ATAAGACTACCGAAGGTTCTTACTGCGGTCTTTGTTGGGGCTGCGTTAGGCATTTCTGGTGCGGTATTTCAATCGGTATC
AAGAAATGCTCTTGGTTCTCCAGATGTCATTGGCTTCACTACGGGGGCTGCGACCGGTGCAATTGCTCAAATAGTTTTGT
TTGAGCAAGGGGCTATCGAAGTGGCAATCGCGGCGATAGTCGGCGGAGTAATCACGGCTGTTATCGTTTACTTACTTGCG
GTAAAAACAGGAGTGGTTGGAGGGTATCGCCTAATACTCACTGGTATTGGGGTCGGGTCCATTTTGAGTGCGCTGAACAG
CCTGATGTTAGTTAAGGGTAATTTAGACAATGCCATTTTGGCCAATCTATGGCTTGCAGGATCACTGCATGCTAGGACAT
GGACACATGTTTATCCTGTACTTATAGGGGTATGTCTCCTCCTCCCTTTTATGATGATGCTAAAGCGTGCGCTTGCCATG
ATAGAGATGGGGGATGACATCGCAACTCAGCTGGGTATCCGAGTAGAGCGAGTCCGTCTTTCTATGATTTTCTTTGCTGT
GGTCTTAGCCGCATTCGCGACAGGAGCTGCTGGGCCTATTGCCTTTATTGCCCTTGCTGCTCCTCAATTAGTTGGTCGAT
TGAGAAAGTCGCGAGCATTATCCTTGTTCTCCTCAGCTCTTATGGGCGCGTTGTTGGTCTTAACCGCGGATGTTTTAATT
CAATGGTTGCCTTTTCAAGCAAGCGTGCCGATAGGCAGGATGACGGGTATTGTAGGTGGCATATATTTAATTTGGCTATT
GACTCGATCTCGCCAGTTTTAA

Upstream 100 bases:

>100_bases
TCGTCGGGTATCCCAATGAGATCAGTGTAGGCATTATGATTGCTCTAATCGGCGGGCCATTCTTTGTATTCTTAGTGAAA
CGTTGGAAGATATCTCTCCT

Downstream 100 bases:

>100_bases
GCATAGGCACTCATATGATTAATGAGAGCGATACTTCTTAAGTTTACCGATTATTTGTCAAGTATATGAGTGTTAGAGCA
AGACTCGTTTTACCGAGTTA

Product: iron-siderophore uptake ABC transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MMIEPYTLQHSGSGSVVRFGQFSFCYQPSHILVALILLISVCAIATYSMTLGKFNISLPQVADITLGVGEGGVKERIILN
IRLPKVLTAVFVGAALGISGAVFQSVSRNALGSPDVIGFTTGAATGAIAQIVLFEQGAIEVAIAAIVGGVITAVIVYLLA
VKTGVVGGYRLILTGIGVGSILSALNSLMLVKGNLDNAILANLWLAGSLHARTWTHVYPVLIGVCLLLPFMMMLKRALAM
IEMGDDIATQLGIRVERVRLSMIFFAVVLAAFATGAAGPIAFIALAAPQLVGRLRKSRALSLFSSALMGALLVLTADVLI
QWLPFQASVPIGRMTGIVGGIYLIWLLTRSRQF

Sequences:

>Translated_353_residues
MMIEPYTLQHSGSGSVVRFGQFSFCYQPSHILVALILLISVCAIATYSMTLGKFNISLPQVADITLGVGEGGVKERIILN
IRLPKVLTAVFVGAALGISGAVFQSVSRNALGSPDVIGFTTGAATGAIAQIVLFEQGAIEVAIAAIVGGVITAVIVYLLA
VKTGVVGGYRLILTGIGVGSILSALNSLMLVKGNLDNAILANLWLAGSLHARTWTHVYPVLIGVCLLLPFMMMLKRALAM
IEMGDDIATQLGIRVERVRLSMIFFAVVLAAFATGAAGPIAFIALAAPQLVGRLRKSRALSLFSSALMGALLVLTADVLI
QWLPFQASVPIGRMTGIVGGIYLIWLLTRSRQF
>Mature_353_residues
MMIEPYTLQHSGSGSVVRFGQFSFCYQPSHILVALILLISVCAIATYSMTLGKFNISLPQVADITLGVGEGGVKERIILN
IRLPKVLTAVFVGAALGISGAVFQSVSRNALGSPDVIGFTTGAATGAIAQIVLFEQGAIEVAIAAIVGGVITAVIVYLLA
VKTGVVGGYRLILTGIGVGSILSALNSLMLVKGNLDNAILANLWLAGSLHARTWTHVYPVLIGVCLLLPFMMMLKRALAM
IEMGDDIATQLGIRVERVRLSMIFFAVVLAAFATGAAGPIAFIALAAPQLVGRLRKSRALSLFSSALMGALLVLTADVLI
QWLPFQASVPIGRMTGIVGGIYLIWLLTRSRQF

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=42.7272727272727, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1790740, Length=323, Percent_Identity=31.8885448916409, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790741, Length=293, Percent_Identity=32.0819112627986, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786347, Length=273, Percent_Identity=27.1062271062271, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=30.6620209059233, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786805, Length=220, Percent_Identity=33.6363636363636, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37194; Mature: 37194

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIEPYTLQHSGSGSVVRFGQFSFCYQPSHILVALILLISVCAIATYSMTLGKFNISLPQ
CCCCCEEEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCC
VADITLGVGEGGVKERIILNIRLPKVLTAVFVGAALGISGAVFQSVSRNALGSPDVIGFT
CEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEE
TGAATGAIAQIVLFEQGAIEVAIAAIVGGVITAVIVYLLAVKTGVVGGYRLILTGIGVGS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHH
ILSALNSLMLVKGNLDNAILANLWLAGSLHARTWTHVYPVLIGVCLLLPFMMMLKRALAM
HHHHHHHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEMGDDIATQLGIRVERVRLSMIFFAVVLAAFATGAAGPIAFIALAAPQLVGRLRKSRAL
HHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLFSSALMGALLVLTADVLIQWLPFQASVPIGRMTGIVGGIYLIWLLTRSRQF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMIEPYTLQHSGSGSVVRFGQFSFCYQPSHILVALILLISVCAIATYSMTLGKFNISLPQ
CCCCCEEEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCC
VADITLGVGEGGVKERIILNIRLPKVLTAVFVGAALGISGAVFQSVSRNALGSPDVIGFT
CEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEE
TGAATGAIAQIVLFEQGAIEVAIAAIVGGVITAVIVYLLAVKTGVVGGYRLILTGIGVGS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHH
ILSALNSLMLVKGNLDNAILANLWLAGSLHARTWTHVYPVLIGVCLLLPFMMMLKRALAM
HHHHHHHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEMGDDIATQLGIRVERVRLSMIFFAVVLAAFATGAAGPIAFIALAAPQLVGRLRKSRAL
HHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLFSSALMGALLVLTADVLIQWLPFQASVPIGRMTGIVGGIYLIWLLTRSRQF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]