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The map label for this gene is nadA [H]

Identifier: 218709113

GI number: 218709113

Start: 1183013

End: 1184074

Strand: Direct

Name: nadA [H]

Synonym: VS_1119

Alternate gene names: 218709113

Gene position: 1183013-1184074 (Clockwise)

Preceding gene: 218709112

Following gene: 218709114

Centisome position: 35.86

GC content: 46.99

Gene sequence:

>1062_bases
ATGAGTCATATACTAGATAAAATCGATACAGTTTACCCGTTTCCGCCTAAGCCAGTTCCACTGAGCGACGCTCAGAAGCA
GGCCCACATCGCAAACATCAAAACACTACTTCAAGAAAAAGATGCAGTACTAATTGCACACTACTACACAGATCCTGAAA
TTCAGGCCCTGGCTGAAGCAACTGGTGGTTTTGTTGGCGATTCATTAGAAATGGCTAAGTTTGGTAACCGCCATTCGGCA
AGCACTTTGATCATCGCTGGCGTTCGTTTTATGGGGGAGTCAGCAAAGATTCTTACACCTGAAAAACGCATTCTAATGCC
AACACTAGAAGCTGAATGTTCTCTTGATCTTGGCTGTCCTGCAGACAAGTTTACAGAATTTTGTGATGCTCACCCTGACC
ATACAGTGGTTGTATACGCGAATACCTCTGCGGCTGTTAAGGCTCGTGCAGACTGGGTAGTTACGTCGAGCATCGCTCTA
GAAATCGTTGAAAGCCTAGACGCTGAAGGCAAACCCATTATTTGGGGTCCAGACCGTCACCTAGGTTCTTACATCGCAAA
TCAAACTGGCGCTGACATGCTGCTTTGGCAAGGTGAGTGTATTGTTCATGACGAGTTCTCAGCTGATGCTTTGAAGAAAA
TGAAATCAGTATACCCAGAAGCGGCTATTTTGGTTCACCCAGAATCACCAGCAAGCGTGGTTGAACTGGCTGACGCTGTT
GGTTCAACAAGTCAACTGATCAAGAAAGCAAAAGAGCTGCCTCATCCACAGATGATTGTCGCGACTGACAAAGGTATATT
CTTCAAAATGCAGCAACTGGTTCCTGAAAAAGAGCTGATTGAAGCGCCGACAGCAGGTGCCGGTGCAACTTGTCGAAGCT
GCGCGCACTGTCCTTGGATGGCAATGAACGGCCTTGAAGCGATTGAAAATGCGCTTGAGAATGGTGGCGAGCAACACGAG
ATCTTCGTTTCTGACGAACTGCGCGTGAAGTCCCTTATCCCATTGAACCGCATGCTAGATTTTGCTGAGCAGCTTAACGT
GCAAGTGAAAGGCAACGCTTAA

Upstream 100 bases:

>100_bases
CATTAGTTAGTCATCGCTTGAAACCAATCCTTTTTGATCCCAATCGCTGTCCTGTGTAGAATACTCTAATTCTCGGAAGA
AGTTGCGTAGAGCAAGAGCA

Downstream 100 bases:

>100_bases
TCTAATGACGTGAGGTTATAAATAATCCAATATTTATAACTATGCAGTCTTTATAATGTGGTGCATTTGTCATCATTAAA
AAACCAGCCGCAGTGCTGGT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSHILDKIDTVYPFPPKPVPLSDAQKQAHIANIKTLLQEKDAVLIAHYYTDPEIQALAEATGGFVGDSLEMAKFGNRHSA
STLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVESLDAEGKPIIWGPDRHLGSYIANQTGADMLLWQGECIVHDEFSADALKKMKSVYPEAAILVHPESPASVVELADAV
GSTSQLIKKAKELPHPQMIVATDKGIFFKMQQLVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLEAIENALENGGEQHE
IFVSDELRVKSLIPLNRMLDFAEQLNVQVKGNA

Sequences:

>Translated_353_residues
MSHILDKIDTVYPFPPKPVPLSDAQKQAHIANIKTLLQEKDAVLIAHYYTDPEIQALAEATGGFVGDSLEMAKFGNRHSA
STLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVESLDAEGKPIIWGPDRHLGSYIANQTGADMLLWQGECIVHDEFSADALKKMKSVYPEAAILVHPESPASVVELADAV
GSTSQLIKKAKELPHPQMIVATDKGIFFKMQQLVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLEAIENALENGGEQHE
IFVSDELRVKSLIPLNRMLDFAEQLNVQVKGNA
>Mature_352_residues
SHILDKIDTVYPFPPKPVPLSDAQKQAHIANIKTLLQEKDAVLIAHYYTDPEIQALAEATGGFVGDSLEMAKFGNRHSAS
TLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALE
IVESLDAEGKPIIWGPDRHLGSYIANQTGADMLLWQGECIVHDEFSADALKKMKSVYPEAAILVHPESPASVVELADAVG
STSQLIKKAKELPHPQMIVATDKGIFFKMQQLVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLEAIENALENGGEQHEI
FVSDELRVKSLIPLNRMLDFAEQLNVQVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=346, Percent_Identity=68.2080924855491, Blast_Score=514, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38364; Mature: 38233

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHILDKIDTVYPFPPKPVPLSDAQKQAHIANIKTLLQEKDAVLIAHYYTDPEIQALAEA
CCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRHSASTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCP
HCCCCCCCHHHHHCCCCCCCCEEEEEEHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVESLDAEGKPIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCHH
LGSYIANQTGADMLLWQGECIVHDEFSADALKKMKSVYPEAAILVHPESPASVVELADAV
HHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHC
GSTSQLIKKAKELPHPQMIVATDKGIFFKMQQLVPEKELIEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLEAIENALENGGEQHEIFVSDELRVKSLIPLNRMLDFAEQLNVQVKGNA
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
SHILDKIDTVYPFPPKPVPLSDAQKQAHIANIKTLLQEKDAVLIAHYYTDPEIQALAEA
CHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRHSASTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCP
HCCCCCCCHHHHHCCCCCCCCEEEEEEHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVESLDAEGKPIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCHH
LGSYIANQTGADMLLWQGECIVHDEFSADALKKMKSVYPEAAILVHPESPASVVELADAV
HHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHC
GSTSQLIKKAKELPHPQMIVATDKGIFFKMQQLVPEKELIEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLEAIENALENGGEQHEIFVSDELRVKSLIPLNRMLDFAEQLNVQVKGNA
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA