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The map label for this gene is flhA [H]

Identifier: 218708837

GI number: 218708837

Start: 858196

End: 860298

Strand: Direct

Name: flhA [H]

Synonym: VS_0837

Alternate gene names: 218708837

Gene position: 858196-860298 (Clockwise)

Preceding gene: 218708836

Following gene: 218708838

Centisome position: 26.01

GC content: 46.6

Gene sequence:

>2103_bases
ATGAAATTCTCCCTGCCTTTTGCGGACAAGCTGCCTAAAATCCCTAATCGTGCGATGCCTGCAATTGGCGCACCCGTTAT
GGTACTTGCGACGCTCGCTATGGTGGTGTTGCCAATACCAGCCTTCTTGTTGGACATGTTCTTCACGTTCAACATTGCAC
TGTCCATGGTTGTGTTACTGGTTTCGGTTTATACCCGCAGGCCTTTGGACTTCGCTGCATTCCCGACCGTACTTCTGATT
GCGACTCTACTTCGATTGGCTTTGAACGTTGCTTCGACACGTGTGGTATTACTCCATGGTCACGAAGGTGGTGACGCGGC
CGGTAACGTTATTGAAGCATTCGGTAACGTGGTTATCGGCGGTAACTACGCGGTAGGTCTAGTGGTGTTTTTGATTTTGA
TGATCATCAACTTCATGGTTGTAACCAAAGGTGCGGGTCGTATTTCGGAAGTAAGTGCGCGTTTCACCCTAGATGCCCTA
CCGGGTAAACAGATGGCAATCGATGCCGACTTGAATGCGGGTTTGATCGACCAAGATCAGGCTCGTACTCGACGTTTTGA
AGTGACCAAAGAGGCCGACTTCTACGGCTCGATGGACGGTGCATCTAAGTTTGTTAAAGGCGATGCAATAGCCGGTATCT
TGATATTGTTCATCAACATCATTGGCGGCTTGAGTATCGGTATGGCTCAGTTTGACCTTGGTTTTGGTGAAGCCATCGAA
ATCTATACGCTACTGACTATCGGTGATGGTCTGGTTGCACAAATACCATCGCTGTTACTTTCTATTGCTGCGGCGATGAT
GGTAACGCGTCAAAATACTGATGAAGACATGGGCGAACAACTTGTCTTCCAAATGTTCGATAATCCTAAAGCCCTAATGA
TCACCGCTGCTATCCTCGGCATCATGGGTATTGTTCCTGGTATGCCACATTTCTCCTTCTTGAGCCTTGCTGTGGTTGCT
GGGGCTGGGGCTTACTTTATCGATAAAAAGAGCAAGGCAAAGGTAGAAGAGAAAAATCTACCTGCAACCGCTAATGCCAA
TGGTGATAAGCCCGCATCGCAAAAAGAACTGTCTTGGGATGATGTTCAACCGGTAGACATTATTGGTCTCGAAGTGGGGT
ACCGCTTGATTCCTTTGGTCGATAGAGACCAAGGTGGTGAATTGCTTGAGCGCGTGAAAGGTGTACGGAAAAAGCTGTCT
CAAGATTTTGGTTTCTTGATTCCAGCAGTACACATTCGCGATAATCTGGAACTGACACCAAACAGCTATCGAATTACCCT
GATGGGGGTAGCGGTTGGTGAGGCTGAGATCAAGCCGGACATGGAGCTCGCGATTAACCCTGGCCAAGTCTATGGGATGA
TAGATGGAGAGCCGACGATTGACCCTGCCTTTGGCCTTGAAGCCGTTTGGATTCGTGAAGAGCAGCGTGAACACGCACAA
GCCTTAGGTTATACGGTTGTAGACTCTTCAACCGTACTTGCCACACACCTTAGCCAGCAGTTAACGAATAACGCTTCACA
GTTGATTGGCCACGAAGAAGTTCAAAACTTACTTGAGATGCTTAGCCGATCAACACCTAAGCTGGTGGAAGGTTTTGTAC
CGGATCAATTACAGCTTGGTGTGGTTGTGAAAGTTCTACAAAACCTACTGAATGAAGCGATTCCAATTCGTGATATTCGA
ACCATTGTCCAAACTTTGTCGGAGTACTCTTCTAAGAGTCAAGAACCTGACATATTAACTGCAGCTGTTCGTATCTCACT
AAAACGACTAATTGTTCAAGAAATCAATGGTATAGAGCCAGAATTACCAGTCATTACTTTAATTCCTGAGTTGGAACAAA
TCTTGCATCAAACCATGCAGGCATCCGGCGGAGAATCTGCTGGTATTGAACCTGGTTTAGCCGAACGTTTACAGACCTCA
CTCAGTAACGCGACACAAGAGCAAGAACTGAAAGGTGAGCCGGCGGTATTATTGACCTCTGGTGTTTTACGTTCGACTCT
GGCTAAGTTCGTGAAAAACACGATCCCAAGCTTGAGAGTATTATCTTACCAAGAGATACCAGACGAAAAGCAGATACGTA
TAGTACAAGCTGTTGGTAATTAA

Upstream 100 bases:

>100_bases
TTGAACCTATGCACTATAAACCATAGCAACATAGCTTAGACCTGAGCTTCAACAAATAGCTTAGTGAGATGGCTACAACA
TAGCGAAACTGTCTAGACTT

Downstream 100 bases:

>100_bases
GCCGCCTAATTAGAACGGACGATCGAATTGAAAATTAAACGATTTTTTGCAAAAGATATGCGAACAGCTCTGCTCCAAGT
TAAAGAAGAACTTGGCTCAG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MKFSLPFADKLPKIPNRAMPAIGAPVMVLATLAMVVLPIPAFLLDMFFTFNIALSMVVLLVSVYTRRPLDFAAFPTVLLI
ATLLRLALNVASTRVVLLHGHEGGDAAGNVIEAFGNVVIGGNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQDQARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMAQFDLGFGEAIE
IYTLLTIGDGLVAQIPSLLLSIAAAMMVTRQNTDEDMGEQLVFQMFDNPKALMITAAILGIMGIVPGMPHFSFLSLAVVA
GAGAYFIDKKSKAKVEEKNLPATANANGDKPASQKELSWDDVQPVDIIGLEVGYRLIPLVDRDQGGELLERVKGVRKKLS
QDFGFLIPAVHIRDNLELTPNSYRITLMGVAVGEAEIKPDMELAINPGQVYGMIDGEPTIDPAFGLEAVWIREEQREHAQ
ALGYTVVDSSTVLATHLSQQLTNNASQLIGHEEVQNLLEMLSRSTPKLVEGFVPDQLQLGVVVKVLQNLLNEAIPIRDIR
TIVQTLSEYSSKSQEPDILTAAVRISLKRLIVQEINGIEPELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQTS
LSNATQEQELKGEPAVLLTSGVLRSTLAKFVKNTIPSLRVLSYQEIPDEKQIRIVQAVGN

Sequences:

>Translated_700_residues
MKFSLPFADKLPKIPNRAMPAIGAPVMVLATLAMVVLPIPAFLLDMFFTFNIALSMVVLLVSVYTRRPLDFAAFPTVLLI
ATLLRLALNVASTRVVLLHGHEGGDAAGNVIEAFGNVVIGGNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQDQARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMAQFDLGFGEAIE
IYTLLTIGDGLVAQIPSLLLSIAAAMMVTRQNTDEDMGEQLVFQMFDNPKALMITAAILGIMGIVPGMPHFSFLSLAVVA
GAGAYFIDKKSKAKVEEKNLPATANANGDKPASQKELSWDDVQPVDIIGLEVGYRLIPLVDRDQGGELLERVKGVRKKLS
QDFGFLIPAVHIRDNLELTPNSYRITLMGVAVGEAEIKPDMELAINPGQVYGMIDGEPTIDPAFGLEAVWIREEQREHAQ
ALGYTVVDSSTVLATHLSQQLTNNASQLIGHEEVQNLLEMLSRSTPKLVEGFVPDQLQLGVVVKVLQNLLNEAIPIRDIR
TIVQTLSEYSSKSQEPDILTAAVRISLKRLIVQEINGIEPELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQTS
LSNATQEQELKGEPAVLLTSGVLRSTLAKFVKNTIPSLRVLSYQEIPDEKQIRIVQAVGN
>Mature_700_residues
MKFSLPFADKLPKIPNRAMPAIGAPVMVLATLAMVVLPIPAFLLDMFFTFNIALSMVVLLVSVYTRRPLDFAAFPTVLLI
ATLLRLALNVASTRVVLLHGHEGGDAAGNVIEAFGNVVIGGNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQDQARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMAQFDLGFGEAIE
IYTLLTIGDGLVAQIPSLLLSIAAAMMVTRQNTDEDMGEQLVFQMFDNPKALMITAAILGIMGIVPGMPHFSFLSLAVVA
GAGAYFIDKKSKAKVEEKNLPATANANGDKPASQKELSWDDVQPVDIIGLEVGYRLIPLVDRDQGGELLERVKGVRKKLS
QDFGFLIPAVHIRDNLELTPNSYRITLMGVAVGEAEIKPDMELAINPGQVYGMIDGEPTIDPAFGLEAVWIREEQREHAQ
ALGYTVVDSSTVLATHLSQQLTNNASQLIGHEEVQNLLEMLSRSTPKLVEGFVPDQLQLGVVVKVLQNLLNEAIPIRDIR
TIVQTLSEYSSKSQEPDILTAAVRISLKRLIVQEINGIEPELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQTS
LSNATQEQELKGEPAVLLTSGVLRSTLAKFVKNTIPSLRVLSYQEIPDEKQIRIVQAVGN

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=679, Percent_Identity=53.3136966126657, Blast_Score=705, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75757; Mature: 75757

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSLPFADKLPKIPNRAMPAIGAPVMVLATLAMVVLPIPAFLLDMFFTFNIALSMVVLL
CCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVYTRRPLDFAAFPTVLLIATLLRLALNVASTRVVLLHGHEGGDAAGNVIEAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCEEEC
GNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQDQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHH
ARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMAQFDLGFGEAIE
HHHHHEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEE
IYTLLTIGDGLVAQIPSLLLSIAAAMMVTRQNTDEDMGEQLVFQMFDNPKALMITAAILG
EEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IMGIVPGMPHFSFLSLAVVAGAGAYFIDKKSKAKVEEKNLPATANANGDKPASQKELSWD
HHHHCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC
DVQPVDIIGLEVGYRLIPLVDRDQGGELLERVKGVRKKLSQDFGFLIPAVHIRDNLELTP
CCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHCCEEEECCCCEECC
NSYRITLMGVAVGEAEIKPDMELAINPGQVYGMIDGEPTIDPAFGLEAVWIREEQREHAQ
CCEEEEEEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHH
ALGYTVVDSSTVLATHLSQQLTNNASQLIGHEEVQNLLEMLSRSTPKLVEGFVPDQLQLG
HHCEEEECCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
VVVKVLQNLLNEAIPIRDIRTIVQTLSEYSSKSQEPDILTAAVRISLKRLIVQEINGIEP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQTSLSNATQEQELKGEPAVLLTS
CCCEEEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
GVLRSTLAKFVKNTIPSLRVLSYQEIPDEKQIRIVQAVGN
HHHHHHHHHHHHHCCCCCEEEEHHHCCCHHHEEEEEECCC
>Mature Secondary Structure
MKFSLPFADKLPKIPNRAMPAIGAPVMVLATLAMVVLPIPAFLLDMFFTFNIALSMVVLL
CCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVYTRRPLDFAAFPTVLLIATLLRLALNVASTRVVLLHGHEGGDAAGNVIEAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCEEEC
GNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQDQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHH
ARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMAQFDLGFGEAIE
HHHHHEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEE
IYTLLTIGDGLVAQIPSLLLSIAAAMMVTRQNTDEDMGEQLVFQMFDNPKALMITAAILG
EEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IMGIVPGMPHFSFLSLAVVAGAGAYFIDKKSKAKVEEKNLPATANANGDKPASQKELSWD
HHHHCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC
DVQPVDIIGLEVGYRLIPLVDRDQGGELLERVKGVRKKLSQDFGFLIPAVHIRDNLELTP
CCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHCCEEEECCCCEECC
NSYRITLMGVAVGEAEIKPDMELAINPGQVYGMIDGEPTIDPAFGLEAVWIREEQREHAQ
CCEEEEEEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHH
ALGYTVVDSSTVLATHLSQQLTNNASQLIGHEEVQNLLEMLSRSTPKLVEGFVPDQLQLG
HHCEEEECCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
VVVKVLQNLLNEAIPIRDIRTIVQTLSEYSSKSQEPDILTAAVRISLKRLIVQEINGIEP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQTSLSNATQEQELKGEPAVLLTS
CCCEEEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
GVLRSTLAKFVKNTIPSLRVLSYQEIPDEKQIRIVQAVGN
HHHHHHHHHHHHHCCCCCEEEEHHHCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]