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The map label for this gene is fabF [H]

Identifier: 218708775

GI number: 218708775

Start: 796665

End: 797864

Strand: Reverse

Name: fabF [H]

Synonym: VS_0773

Alternate gene names: 218708775

Gene position: 797864-796665 (Counterclockwise)

Preceding gene: 218708776

Following gene: 218708774

Centisome position: 24.18

GC content: 45.08

Gene sequence:

>1200_bases
ATGCCTATTTATATCCAAGACTGTGGTTTCCACTCCGCATTAGGCTCAAGCGTTGCTGACATTCATGGCTGCCTCAAAGG
CGAGCATGAATCAAACATGGTTGAAGTGAGCGACATGCTAAACGACGGTAAGCCGACGGTCGTTGGTAAGGTGGCTGGCG
AATTACCAGAAATCCCATCAGAACAAGCGGAATACGCCACTCGCAACAATCAACTGGCGTTATCGGCTGTTAATCAAATC
AAAGACTCTATCGAGCAAGCAAAATCACAATTTGGTGCCGATAGAATTGCTGTAGTTATCGGCACAAGCACCTCGGGAAT
TTCTGATGGTGAAACTGCGTTTAAACACAAACTAGAACATGGCTCTTTCCCCGAAGGTTTCCACTATTCAAAACAAGAGC
TAAGCAACACCTCTGAGTTTGTTAGCCAACATTGTGCATTAACCGGGCCAAGCTATGCGATATCGACCGCTTGCTCATCA
AGTGGCCGTGTATTTGTTACTGCACAACGTTTGTTAGATTCAGGAATGGCTGATGCTGTGTTGGTTGGAGGTGTCGATAC
ACTATGTAAACTGACGCTCAATGGCTTTCATGGTCTTGAAGCGCTATCAACCACACATTGTAAGCCCTTTAGCGCCTCTC
GTGATGGCATCAACATCGGAGAAGCTGCGGCATTTATGTTGCTTAGCAAGACAAAACCAACCGCTACCAATACAACTCAA
AGCACTTCGAATATAGCCCTATTAGGCTATGGCGACAGCTCCGACGCACACCATATTTCCGCGCCCCATCCAGAAGGGAA
CGGTGCAGAACAAGCAATGAGAAAGGCGTTAGATTCTGCACAGTTACGAGCAAAAGACATCGGTTATATTAATGCCCATG
GCACCGCAACCCCACTCAATGATTCAATGGAAAGCAAAGCCATCCATCGTATTTTTGCAAACAAGGTTCCCGTCAGTTCA
ACCAAGCCTCTAACAGGACATACTCTTGGAGCGGCAAGTGCGATAGAGGCTGCAATTGCGTGGCATATTCTAAAATATGA
CTTACCACTCCCCTTACAAAAATGTCAGTATAAAGCTGAAGATATTGAGATTGATTTGGTAAACTGTTCCCAGAAACTTA
AAGTAAAGAACATCTTAAGCAACTCGTTCGCTTTTGGTGGCAACAACATTAGCCTGATTTTTGGTGTAATAAATGACTGA

Upstream 100 bases:

>100_bases
CAGGCAACATTGTTTTCAAGCATTTGATTCAAGGCTACACCATCACGATACAAACGTTGAACTCAACGATTGTCGATAAC
CCAAGTAAGAGCTAAACATC

Downstream 100 bases:

>100_bases
TATCCCTTCTGTAGACCAACTTCTCCCACACGATGATCCGATGATATTAATCGATCGAGCTATCGACGTTGAGGCATTGT
CGATTCACTGCCAGGTCGAT

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPIYIQDCGFHSALGSSVADIHGCLKGEHESNMVEVSDMLNDGKPTVVGKVAGELPEIPSEQAEYATRNNQLALSAVNQI
KDSIEQAKSQFGADRIAVVIGTSTSGISDGETAFKHKLEHGSFPEGFHYSKQELSNTSEFVSQHCALTGPSYAISTACSS
SGRVFVTAQRLLDSGMADAVLVGGVDTLCKLTLNGFHGLEALSTTHCKPFSASRDGINIGEAAAFMLLSKTKPTATNTTQ
STSNIALLGYGDSSDAHHISAPHPEGNGAEQAMRKALDSAQLRAKDIGYINAHGTATPLNDSMESKAIHRIFANKVPVSS
TKPLTGHTLGAASAIEAAIAWHILKYDLPLPLQKCQYKAEDIEIDLVNCSQKLKVKNILSNSFAFGGNNISLIFGVIND

Sequences:

>Translated_399_residues
MPIYIQDCGFHSALGSSVADIHGCLKGEHESNMVEVSDMLNDGKPTVVGKVAGELPEIPSEQAEYATRNNQLALSAVNQI
KDSIEQAKSQFGADRIAVVIGTSTSGISDGETAFKHKLEHGSFPEGFHYSKQELSNTSEFVSQHCALTGPSYAISTACSS
SGRVFVTAQRLLDSGMADAVLVGGVDTLCKLTLNGFHGLEALSTTHCKPFSASRDGINIGEAAAFMLLSKTKPTATNTTQ
STSNIALLGYGDSSDAHHISAPHPEGNGAEQAMRKALDSAQLRAKDIGYINAHGTATPLNDSMESKAIHRIFANKVPVSS
TKPLTGHTLGAASAIEAAIAWHILKYDLPLPLQKCQYKAEDIEIDLVNCSQKLKVKNILSNSFAFGGNNISLIFGVIND
>Mature_398_residues
PIYIQDCGFHSALGSSVADIHGCLKGEHESNMVEVSDMLNDGKPTVVGKVAGELPEIPSEQAEYATRNNQLALSAVNQIK
DSIEQAKSQFGADRIAVVIGTSTSGISDGETAFKHKLEHGSFPEGFHYSKQELSNTSEFVSQHCALTGPSYAISTACSSS
GRVFVTAQRLLDSGMADAVLVGGVDTLCKLTLNGFHGLEALSTTHCKPFSASRDGINIGEAAAFMLLSKTKPTATNTTQS
TSNIALLGYGDSSDAHHISAPHPEGNGAEQAMRKALDSAQLRAKDIGYINAHGTATPLNDSMESKAIHRIFANKVPVSST
KPLTGHTLGAASAIEAAIAWHILKYDLPLPLQKCQYKAEDIEIDLVNCSQKLKVKNILSNSFAFGGNNISLIFGVIND

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=397, Percent_Identity=33.7531486146096, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=42.7586206896552, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI41872631, Length=261, Percent_Identity=31.0344827586207, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1787337, Length=260, Percent_Identity=37.3076923076923, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788663, Length=282, Percent_Identity=28.7234042553192, Blast_Score=114, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71983541, Length=366, Percent_Identity=29.7814207650273, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71983535, Length=260, Percent_Identity=31.5384615384615, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=357, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320904, Length=271, Percent_Identity=33.5793357933579, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24644341, Length=268, Percent_Identity=36.5671641791045, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI19920632, Length=261, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221330659, Length=263, Percent_Identity=27.3764258555133, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42288; Mature: 42157

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIYIQDCGFHSALGSSVADIHGCLKGEHESNMVEVSDMLNDGKPTVVGKVAGELPEIPS
CCEEEECCCCHHHHCCHHHHHHHHHCCCCCCCEEEHHHHHCCCCCEEEEHHHCCCCCCCC
EQAEYATRNNQLALSAVNQIKDSIEQAKSQFGADRIAVVIGTSTSGISDGETAFKHKLEH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCC
GSFPEGFHYSKQELSNTSEFVSQHCALTGPSYAISTACSSSGRVFVTAQRLLDSGMADAV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCCCEEEEEHHHHCCCCCCEE
LVGGVDTLCKLTLNGFHGLEALSTTHCKPFSASRDGINIGEAAAFMLLSKTKPTATNTTQ
EECCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
STSNIALLGYGDSSDAHHISAPHPEGNGAEQAMRKALDSAQLRAKDIGYINAHGTATPLN
CCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCC
DSMESKAIHRIFANKVPVSSTKPLTGHTLGAASAIEAAIAWHILKYDLPLPLQKCQYKAE
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCCC
DIEIDLVNCSQKLKVKNILSNSFAFGGNNISLIFGVIND
CEEEEEECCCCHHHHHHHHHCCCEECCCCEEEEEEEECC
>Mature Secondary Structure 
PIYIQDCGFHSALGSSVADIHGCLKGEHESNMVEVSDMLNDGKPTVVGKVAGELPEIPS
CEEEECCCCHHHHCCHHHHHHHHHCCCCCCCEEEHHHHHCCCCCEEEEHHHCCCCCCCC
EQAEYATRNNQLALSAVNQIKDSIEQAKSQFGADRIAVVIGTSTSGISDGETAFKHKLEH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCC
GSFPEGFHYSKQELSNTSEFVSQHCALTGPSYAISTACSSSGRVFVTAQRLLDSGMADAV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCCCEEEEEHHHHCCCCCCEE
LVGGVDTLCKLTLNGFHGLEALSTTHCKPFSASRDGINIGEAAAFMLLSKTKPTATNTTQ
EECCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
STSNIALLGYGDSSDAHHISAPHPEGNGAEQAMRKALDSAQLRAKDIGYINAHGTATPLN
CCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCC
DSMESKAIHRIFANKVPVSSTKPLTGHTLGAASAIEAAIAWHILKYDLPLPLQKCQYKAE
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCCC
DIEIDLVNCSQKLKVKNILSNSFAFGGNNISLIFGVIND
CEEEEEECCCCHHHHHHHHHCCCEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA