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The map label for this gene is yocR [H]

Identifier: 218708727

GI number: 218708727

Start: 740859

End: 742220

Strand: Direct

Name: yocR [H]

Synonym: VS_0706

Alternate gene names: 218708727

Gene position: 740859-742220 (Clockwise)

Preceding gene: 218708726

Following gene: 218708740

Centisome position: 22.46

GC content: 45.74

Gene sequence:

>1362_bases
ATGGACCAACAATCTTCCTCTTCAAGAGAGCACTTTAGCTCTCGTTTGGGTTTTATTTTAGCAGCGGCGGGTGCAGCTGT
TGGCTTAGGTAATATTTGGGGTTTCCCAACCCAAGTCGCCAGTAACGGCGGTGGTGCTTTTCTGCTTGTTTACCTAATTA
TGATTTTCGTGGTTGCTTTCCCGATGCTGGTGGTTGAGATGGCTATTGGTCGACATGGCCAAGCAAATCCTGTCGATAGC
ATGCGTTCTTTGACTACAAACCCGTTAGGCAAGAAAGTCGGTGAATTTGTCGGTTGGATTGGGTTGAGTGTTCCAAGTGC
AGTGCTAGCGTTTTATAGCATTGTCGGTGGTTGGTTGATCTGCTTCCTAATTGGTGCTGTCGCTGACCTGATTGGTCTAG
AGGCCGCTGCTGATTGGTTTAAAGGCTTCAGTGTTGAGCGCAATGTTTTTGGTACCGTCGCATTCTATGTGCTGACTATC
TTGATTGTTCAGGGCGGTGTTAAGCAGGGGATCGAGAAATGGTCGACCCGTTTGATGCCTGCGCTATTTGTGTTATTTGG
CTTATTGTTTGTTTACATCATGACGCAATCTGGCGCGATGGAAGGCCTAAAGCATTACCTCGTTCCAGACTTTGAGAAAG
TGTGGGATAGAAAACTGATTTTGGCAGCTATGGGGCAGGGCTTCTTCTCGCTCACTATTGGTGGTTGCTCGATGTTGGTT
TATGGCTCTTACTTAAGTAAGAAAGAGAACCTGCCAAAAATGGCAATGAACGTTACCTTAGTTGATACCGCGGTTGCTTT
TATTGCGGGCTTAGTCGTGATGCCTGCCATGTTTGTTGCGATGCAAAAAGGTGTTCAAATCTATGCTGAAGATGGCTCAT
TACTGAGCTCTGATACCCTAGTATTTACGGTTCTGCCTTTGATGTTTGATAGCTTAGGTATGCTGGGTCAGGTCTTCGCA
ATTGTGTTTTTCTTATTGCTAACGATTGCTGCACTTACTTCATCTATTTCAATGTTGGAAGCCCCTGTCGCTCTTGTTAG
TGAGCGTTTTAAGACCAGACGAACGCCAACAAGTTGGGTAATTGGTGGTGCTATCGCATTGTTCAGTGTGGTGATTGTTT
ACAACTTTGCCGCTATGTTTGGCATGGTTGCGATGATTGCGACTCAGTACCTTCAACCAGTCGCTGCACTGATGTTCTGT
GTGTTTGGTGGTTGGGTATGGAGCCGAGCTTCAAAAGTGAAAGAACTTGAACAAGGTTGTCCTGATTTTCAACTTGGTTG
GTTTGGTAAGGTTTGGCCAATGTATGTGAAGTTCGTGTGCCCAATTTTAGTCGCAACGGTTATCTGGGCATCTTTTGGCT
AG

Upstream 100 bases:

>100_bases
GTTGTAAAAACTAGAAGATCGCTCATTTATTAGTTGTGCCTATCATTGCTTTTGATTACTGTACTTCTCAACTAGTTCAC
TGATTTTTAATGCGGGCAAT

Downstream 100 bases:

>100_bases
TAGACCATTTAACATCTAGATGATTAGACTTGCAGTTCAAGGCCACTCTTAATGAGTGGCTTTGTTGTTTTTGTATCGAA
CAAGCTTGTTCGATACAAAA

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDQQSSSSREHFSSRLGFILAAAGAAVGLGNIWGFPTQVASNGGGAFLLVYLIMIFVVAFPMLVVEMAIGRHGQANPVDS
MRSLTTNPLGKKVGEFVGWIGLSVPSAVLAFYSIVGGWLICFLIGAVADLIGLEAAADWFKGFSVERNVFGTVAFYVLTI
LIVQGGVKQGIEKWSTRLMPALFVLFGLLFVYIMTQSGAMEGLKHYLVPDFEKVWDRKLILAAMGQGFFSLTIGGCSMLV
YGSYLSKKENLPKMAMNVTLVDTAVAFIAGLVVMPAMFVAMQKGVQIYAEDGSLLSSDTLVFTVLPLMFDSLGMLGQVFA
IVFFLLLTIAALTSSISMLEAPVALVSERFKTRRTPTSWVIGGAIALFSVVIVYNFAAMFGMVAMIATQYLQPVAALMFC
VFGGWVWSRASKVKELEQGCPDFQLGWFGKVWPMYVKFVCPILVATVIWASFG

Sequences:

>Translated_453_residues
MDQQSSSSREHFSSRLGFILAAAGAAVGLGNIWGFPTQVASNGGGAFLLVYLIMIFVVAFPMLVVEMAIGRHGQANPVDS
MRSLTTNPLGKKVGEFVGWIGLSVPSAVLAFYSIVGGWLICFLIGAVADLIGLEAAADWFKGFSVERNVFGTVAFYVLTI
LIVQGGVKQGIEKWSTRLMPALFVLFGLLFVYIMTQSGAMEGLKHYLVPDFEKVWDRKLILAAMGQGFFSLTIGGCSMLV
YGSYLSKKENLPKMAMNVTLVDTAVAFIAGLVVMPAMFVAMQKGVQIYAEDGSLLSSDTLVFTVLPLMFDSLGMLGQVFA
IVFFLLLTIAALTSSISMLEAPVALVSERFKTRRTPTSWVIGGAIALFSVVIVYNFAAMFGMVAMIATQYLQPVAALMFC
VFGGWVWSRASKVKELEQGCPDFQLGWFGKVWPMYVKFVCPILVATVIWASFG
>Mature_453_residues
MDQQSSSSREHFSSRLGFILAAAGAAVGLGNIWGFPTQVASNGGGAFLLVYLIMIFVVAFPMLVVEMAIGRHGQANPVDS
MRSLTTNPLGKKVGEFVGWIGLSVPSAVLAFYSIVGGWLICFLIGAVADLIGLEAAADWFKGFSVERNVFGTVAFYVLTI
LIVQGGVKQGIEKWSTRLMPALFVLFGLLFVYIMTQSGAMEGLKHYLVPDFEKVWDRKLILAAMGQGFFSLTIGGCSMLV
YGSYLSKKENLPKMAMNVTLVDTAVAFIAGLVVMPAMFVAMQKGVQIYAEDGSLLSSDTLVFTVLPLMFDSLGMLGQVFA
IVFFLLLTIAALTSSISMLEAPVALVSERFKTRRTPTSWVIGGAIALFSVVIVYNFAAMFGMVAMIATQYLQPVAALMFC
VFGGWVWSRASKVKELEQGCPDFQLGWFGKVWPMYVKFVCPILVATVIWASFG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=404, Percent_Identity=24.2574257425743, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI4507043, Length=419, Percent_Identity=25.0596658711217, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI134304856, Length=456, Percent_Identity=23.2456140350877, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI171184408, Length=400, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI171184406, Length=400, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI171184404, Length=400, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4507041, Length=404, Percent_Identity=24.7524752475248, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI7657587, Length=393, Percent_Identity=23.9185750636132, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI197276623, Length=344, Percent_Identity=25.2906976744186, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI54607094, Length=344, Percent_Identity=25.2906976744186, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI11181770, Length=304, Percent_Identity=25.3289473684211, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI289191351, Length=402, Percent_Identity=23.8805970149254, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4557046, Length=402, Percent_Identity=23.8805970149254, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI289191377, Length=402, Percent_Identity=23.8805970149254, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI58219014, Length=314, Percent_Identity=24.203821656051, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI194018524, Length=300, Percent_Identity=25.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI12408638, Length=272, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI33354281, Length=305, Percent_Identity=22.6229508196721, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI67782317, Length=342, Percent_Identity=23.9766081871345, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI67782313, Length=341, Percent_Identity=24.0469208211144, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI67782315, Length=342, Percent_Identity=23.9766081871345, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI51468073, Length=330, Percent_Identity=21.5151515151515, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI92859670, Length=85, Percent_Identity=40, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21361693, Length=113, Percent_Identity=33.6283185840708, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI6005715, Length=93, Percent_Identity=37.6344086021505, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI197276625, Length=65, Percent_Identity=46.1538461538462, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71995588, Length=390, Percent_Identity=24.8717948717949, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17554804, Length=376, Percent_Identity=27.6595744680851, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25146584, Length=408, Percent_Identity=23.5294117647059, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17535731, Length=145, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI212642127, Length=123, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17542050, Length=126, Percent_Identity=30.1587301587302, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555248, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19921352, Length=409, Percent_Identity=23.7163814180929, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24584353, Length=409, Percent_Identity=23.7163814180929, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24762620, Length=388, Percent_Identity=25.7731958762887, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24652942, Length=393, Percent_Identity=24.6819338422392, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45551088, Length=393, Percent_Identity=24.6819338422392, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17136952, Length=485, Percent_Identity=23.7113402061856, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24639514, Length=509, Percent_Identity=23.3791748526523, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221329674, Length=509, Percent_Identity=23.3791748526523, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24661428, Length=390, Percent_Identity=24.1025641025641, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24639516, Length=528, Percent_Identity=22.9166666666667, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281364394, Length=485, Percent_Identity=23.7113402061856, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28574704, Length=485, Percent_Identity=23.7113402061856, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17136950, Length=485, Percent_Identity=23.7113402061856, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28574702, Length=485, Percent_Identity=23.7113402061856, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281364136, Length=446, Percent_Identity=24.6636771300448, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639853, Length=405, Percent_Identity=24.1975308641975, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24655079, Length=304, Percent_Identity=25.6578947368421, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363702, Length=499, Percent_Identity=21.4428857715431, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24654186, Length=292, Percent_Identity=27.3972602739726, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281365034, Length=194, Percent_Identity=27.8350515463918, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550877, Length=64, Percent_Identity=46.875, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45551183, Length=64, Percent_Identity=46.875, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49105; Mature: 49105

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]