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The map label for this gene is surA [H]

Identifier: 218708410

GI number: 218708410

Start: 369873

End: 371168

Strand: Reverse

Name: surA [H]

Synonym: VS_0372

Alternate gene names: 218708410

Gene position: 371168-369873 (Counterclockwise)

Preceding gene: 218708411

Following gene: 218708409

Centisome position: 11.25

GC content: 43.44

Gene sequence:

>1296_bases
ATGACATTGTGGAAACGCACATTAATAGCTATCGCAGCGGCTTGTACTTTATCAACAAGCTATGCCGCACCAGTTGAACT
CGATAGCGTAAAAGTAATCGTCAACGAGGGCGTGATCTTACAAAGTGACATTGATACTTCAATGAAAACACTACGCGCAA
ATGCAAAGAAAAGCGGACAAACATTACCATCACAAGATGTACTGAATGAACAAGTTCTAGAAAAGCTGATCATTGATACC
ATTCAGACTCAAGAAGCGGAACGTATTGGGGTTCGAATTGATGATGCTCGACTGGATCAAGCGATTGAAGGCATTGCAAA
AGATAACAACCAAACAGTACAACAACTTACTGCATCGGTTGCTGAAGAAGGCCTTAGCTACAACGCATTTCGTGAGCAAG
TAAGAAAAGAGATTGCAGCAAGTGAAGCTCGTAATGCCTTGGTTCGCCGCCGTATTAATATCCTTCCTGCAGAAGTAGAC
AACCTAGCGGACATCTTAGCGCAAGAAACCAATGCGACGGTTCAATACAAAATTGGCCACATCCAACTTCGATTCAATGA
TGACCAAACCAAAGAAGAGTTAGAAGCACAAGCGACTGATTTAGTGGAAGAGCTAAACAACGGCAAAGACTTTAGCACCA
TGGCATATACATACTCTAAAGGCCCTAAAGCGTTACAAGGTGGTGATTGGGGTTGGATGCGTAAAGAAGAGATGCCTACG
ATTTTTGCAGACCAAATCAAAATGCAGAATAAAGGCAGCATCATCGGTCCTTTCCGAAGTGGTGTTGGCTTCCATATTCT
AAAAATTGAAGACGTAAAAGGTTTGGAAACCGTTGCAGTTACCGAAGTTAATGCACGTCATATTTTGATTAAGCCAACGG
TTATCTTGAGTGATGACGGTGCGAAAGAGCAGCTTGAAGAAATCACTCGTCGTGTAAACGCAGGTGAAGCGAGCTTTGGT
GATCTTGCACAGCAATACAGCCAAGATCCAGGTTCAGCAGTACAAGATGGTGAGTTAGGCTACCAAACTCCAGATTTATA
CGTTCCTGAGTTCAAACACCAAGTAGAAACGCTACCTGAAGGTAAGATCAGTGCGCCATTCAAAACCGTGCACGGTTGGC
ACATTGTTGAAGTACTAGACCGTCGCGAAGTCGACCGTACCGATTCAGCATTGAAAAACAAAGCTTATCAAATTCTATTT
AACCGTAAGTTCAACGAAGAAGTCGGTGCTTGGCTGCAAGAAGTAAGAGCTAGCGCCTTTGTTGAAGTGGTCGAGGATGA
CCAAGATGACAACTAG

Upstream 100 bases:

>100_bases
GAAACAAGCTCAAGTAACGCACTCAGCTACGGTCGCCCATTCTTCTTAAACAACTAATTTTCTTTATTGATAACACATCG
GTAAATATAAAGGATTACAC

Downstream 100 bases:

>100_bases
ACGCCTTGTCATTACAGCAGGTGAACCGGCGGGAATTGGGCCAGATTTAACTCTCGCATTATCCCAAGAAAGCTGGCCAC
ATCAGCTCGTGGTTTGTGCG

Product: putative parvulin-like peptidyl-prolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTLWKRTLIAIAAACTLSTSYAAPVELDSVKVIVNEGVILQSDIDTSMKTLRANAKKSGQTLPSQDVLNEQVLEKLIIDT
IQTQEAERIGVRIDDARLDQAIEGIAKDNNQTVQQLTASVAEEGLSYNAFREQVRKEIAASEARNALVRRRINILPAEVD
NLADILAQETNATVQYKIGHIQLRFNDDQTKEELEAQATDLVEELNNGKDFSTMAYTYSKGPKALQGGDWGWMRKEEMPT
IFADQIKMQNKGSIIGPFRSGVGFHILKIEDVKGLETVAVTEVNARHILIKPTVILSDDGAKEQLEEITRRVNAGEASFG
DLAQQYSQDPGSAVQDGELGYQTPDLYVPEFKHQVETLPEGKISAPFKTVHGWHIVEVLDRREVDRTDSALKNKAYQILF
NRKFNEEVGAWLQEVRASAFVEVVEDDQDDN

Sequences:

>Translated_431_residues
MTLWKRTLIAIAAACTLSTSYAAPVELDSVKVIVNEGVILQSDIDTSMKTLRANAKKSGQTLPSQDVLNEQVLEKLIIDT
IQTQEAERIGVRIDDARLDQAIEGIAKDNNQTVQQLTASVAEEGLSYNAFREQVRKEIAASEARNALVRRRINILPAEVD
NLADILAQETNATVQYKIGHIQLRFNDDQTKEELEAQATDLVEELNNGKDFSTMAYTYSKGPKALQGGDWGWMRKEEMPT
IFADQIKMQNKGSIIGPFRSGVGFHILKIEDVKGLETVAVTEVNARHILIKPTVILSDDGAKEQLEEITRRVNAGEASFG
DLAQQYSQDPGSAVQDGELGYQTPDLYVPEFKHQVETLPEGKISAPFKTVHGWHIVEVLDRREVDRTDSALKNKAYQILF
NRKFNEEVGAWLQEVRASAFVEVVEDDQDDN
>Mature_430_residues
TLWKRTLIAIAAACTLSTSYAAPVELDSVKVIVNEGVILQSDIDTSMKTLRANAKKSGQTLPSQDVLNEQVLEKLIIDTI
QTQEAERIGVRIDDARLDQAIEGIAKDNNQTVQQLTASVAEEGLSYNAFREQVRKEIAASEARNALVRRRINILPAEVDN
LADILAQETNATVQYKIGHIQLRFNDDQTKEELEAQATDLVEELNNGKDFSTMAYTYSKGPKALQGGDWGWMRKEEMPTI
FADQIKMQNKGSIIGPFRSGVGFHILKIEDVKGLETVAVTEVNARHILIKPTVILSDDGAKEQLEEITRRVNAGEASFGD
LAQQYSQDPGSAVQDGELGYQTPDLYVPEFKHQVETLPEGKISAPFKTVHGWHIVEVLDRREVDRTDSALKNKAYQILFN
RKFNEEVGAWLQEVRASAFVEVVEDDQDDN

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=430, Percent_Identity=44.6511627906977, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48070; Mature: 47938

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLWKRTLIAIAAACTLSTSYAAPVELDSVKVIVNEGVILQSDIDTSMKTLRANAKKSGQ
CCHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCEEEECCCHHHHHHHHHHHHHCCC
TLPSQDVLNEQVLEKLIIDTIQTQEAERIGVRIDDARLDQAIEGIAKDNNQTVQQLTASV
CCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHH
AEEGLSYNAFREQVRKEIAASEARNALVRRRINILPAEVDNLADILAQETNATVQYKIGH
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEE
IQLRFNDDQTKEELEAQATDLVEELNNGKDFSTMAYTYSKGPKALQGGDWGWMRKEEMPT
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHCCCH
IFADQIKMQNKGSIIGPFRSGVGFHILKIEDVKGLETVAVTEVNARHILIKPTVILSDDG
HHHHHHHCCCCCCEECCHHCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEEEEECCCC
AKEQLEEITRRVNAGEASFGDLAQQYSQDPGSAVQDGELGYQTPDLYVPEFKHQVETLPE
CHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
GKISAPFKTVHGWHIVEVLDRREVDRTDSALKNKAYQILFNRKFNEEVGAWLQEVRASAF
CCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
VEVVEDDQDDN
HHHHCCCCCCC
>Mature Secondary Structure 
TLWKRTLIAIAAACTLSTSYAAPVELDSVKVIVNEGVILQSDIDTSMKTLRANAKKSGQ
CHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCEEEECCCHHHHHHHHHHHHHCCC
TLPSQDVLNEQVLEKLIIDTIQTQEAERIGVRIDDARLDQAIEGIAKDNNQTVQQLTASV
CCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHH
AEEGLSYNAFREQVRKEIAASEARNALVRRRINILPAEVDNLADILAQETNATVQYKIGH
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEE
IQLRFNDDQTKEELEAQATDLVEELNNGKDFSTMAYTYSKGPKALQGGDWGWMRKEEMPT
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHCCCH
IFADQIKMQNKGSIIGPFRSGVGFHILKIEDVKGLETVAVTEVNARHILIKPTVILSDDG
HHHHHHHCCCCCCEECCHHCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEEEEECCCC
AKEQLEEITRRVNAGEASFGDLAQQYSQDPGSAVQDGELGYQTPDLYVPEFKHQVETLPE
CHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
GKISAPFKTVHGWHIVEVLDRREVDRTDSALKNKAYQILFNRKFNEEVGAWLQEVRASAF
CCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
VEVVEDDQDDN
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA