Click here to switch to the map view.

The map label for this gene is yagR [H]

Identifier: 218703564

GI number: 218703564

Start: 341149

End: 343347

Strand: Reverse

Name: yagR [H]

Synonym: ECUMN_0315

Alternate gene names: 218703564

Gene position: 343347-341149 (Counterclockwise)

Preceding gene: 218703565

Following gene: 218703563

Centisome position: 6.6

GC content: 59.03

Gene sequence:

>2199_bases
ATGAAATTTGATAAACCCGCAGGGGAAAACCCGATCGATCAGCTGAAGGTTGTCGGTCGTCCCCATGACCGCATCGACGG
ACCGCTGAAAACTACCGGCACGGCACGCTACGCCTACGAATGGTATGAAGAAGCTCCCAACGCCGCCTATGGTTATATCG
TCGGTTCCGCCATTGCCAAAGGATGCCTCACCGCCCTTGATACGGACGCCGCGCAAAAAGCGCCGGGCGTACTGGCTGTC
ATTACCGCCAGTAACGCCGGGGCACTCGGCAAAGGCGACAAAAACACCGCCAGGCTGTTAGCCGGCCCCACTATTGAGCA
CTATCATCAGGCCATTGCGCTGGTAGTGGCCGAGACCTTCGAACAGGCACGAGCGGCGGCCTCGCTGGTGCAGGCGCACT
ATCGCCGTAATAAAGGAGCTTACTCCCTGGCGGACGAGAAACAGGCCGTCAGTCAGCCGCCGGAAGACACGCCCGATAAA
AATGTTGGTGACTTTGACGGGGCTTTCACCTCCGCTGCGGTGAAGATTGATGCTACCTACACGACCCCGGACCAGAGCCA
TATGGCGATGGAGCCGCATGCCTCGATGGCCGTCTGGGATGGAAATAAGCTTACCCTCTGGACCTCAAATCAGATGATTG
ACTGGTGCCGCACCGATCTGGCAAAAACGCTGAAAGTGCCCGTGGAGAATGTGCGTATTATCTCCCCGTATATCGGCGGA
GGGTTTGGCGGCAAGCTGTTCCTGAGAAGCGATGCGCTGCTGGCGGCCCTCGCCGCCCGTGCGGTGAAACGTCCGGTTAA
AGTGATGCTCCCCCGCCCCACTATTCCCAATAACACAACGCACCGCCCCGCCACCCTTCAGCACCTGCGTATCGGTGCCG
ACCAGAGCGGGAAAATCACTGCTATCTCACATGAAAGCTGGTCCGGAAACCTGCCCGGCGGCACGCCGGAAACGGCGGTA
CAGCAAAGCGAATTACTCTACGCAGGGGCGAATCGTCATACCGGCCTGCGGCTCGCCACGCTTGATTTGCCGGAAGGGAA
CGCCATGCGTGCGCCCGGCGAAGCCCCCGGTCTGATGGCGCTCGAAATCGCGATCGATGAACTGGCGGAAAAAGCAGGCA
TCGATCCCGTCGAGTTTCGCATCCTGAATGACACTCAGGTTGACCCCGCCGACCCGACGCGCCGCTTCTCTCGCCGTCAG
CTTATTGAGTGCTTGCGCACCGGAGCGGATAAATTTGGCTGGAAGCAGCGCAACGCCACACCCGGACAGGTACGCGACGG
GGAGTGGCTAGTCGGCCACGGTGTTGCGGCGGGCTTTCGCAATAATCTGCTGGAAAAATCGGGTGCTCGGGTTCACCTAG
AACAAAACGGCACCGTTACCGTGGAAACGGACATGACCGATATTGGCACCGGCAGCTACACAATTCTGGCTCAGACGGCA
GCGGAAATGCTTGGCGTACCGCTGGAGCAGGTTGCGGTTCACCTCGGCGATTCCAGTTTCCCGGTTTCTGCGGGTTCTGG
TGGACAATGGGGCGCGAATACCTCCACCTCCGGCGTTTACGCCGCCTGTGTGAAACTTCGCGAAATGATTGCCTCGGCAG
TCGGGTTTGATCCTGGGCAGTCGCAGTTTGCCGACGGCAAGATTACCAACGGTACCCGAAGCGCCACGCTACATGAGGCC
ACCGCAGGCGGCAGGCTGACAGCGGAAGAGAGCATTGAATTCGGAACACTGAGCAAGGAGTACCAGCAATCGACCTTTGC
CGGGCATTTTGTGGAGGTCGGCGTGCATAGCGCGACGGGAGAAGTTCGGGTCCGGCGTATGCTCGCTGTGTGTGCTGCAG
TACGCATCCTGAATCCGAAAACCGCACGCAGCCAGGTCATTGGCGCAATGACTATGGGCATGGGCGCGGCACTGATGGAG
GAGCTGGCGGTGGATGACCGTTTGGGCTACTTCGTTAATCACGATATGGCGGGGTATGAGGTGCCGGTTCATGCGGATAT
CCCAAAACAGGAGGTGATTTTCCTGGATGATACCGACCCCATCTCCTCCCCGATGAAGGCCAAAGGTGTCGGTGAGCTGG
GCCTGTGCGGCGTGAGCGCGGCTATCGCCAACGCGGTGTATAACGCCACCGGTATTCGGGTACGGGATTATCCCATCACT
CTGGATAAGCTGCTCGATAAACTGCCGGATGTGGTTTAA

Upstream 100 bases:

>100_bases
CGCTGTTCGCCAGCGCCCATCCCACCGCTGAAAACACCTTTAAACTCCTGTTGGCGAAGCGAACGCTTGCCTCCGTACTG
GCTGAAGCGAGGGCACAGGC

Downstream 100 bases:

>100_bases
GGAGGAACAATGTCATACTCGCTTTTTGACAAAGACGAGCACTGGCATAAGCCAGAGCAGGCGTTTCTCACCGATGACCA
CCGGACCATTCTGCGCTTCG

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWYEEAPNAAYGYIVGSAIAKGCLTALDTDAAQKAPGVLAV
ITASNAGALGKGDKNTARLLAGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPTIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRRFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPGQSQFADGKITNGTRSATLHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAVRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV

Sequences:

>Translated_732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWYEEAPNAAYGYIVGSAIAKGCLTALDTDAAQKAPGVLAV
ITASNAGALGKGDKNTARLLAGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPTIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRRFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPGQSQFADGKITNGTRSATLHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAVRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV
>Mature_732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWYEEAPNAAYGYIVGSAIAKGCLTALDTDAAQKAPGVLAV
ITASNAGALGKGDKNTARLLAGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPTIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRRFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPGQSQFADGKITNGTRSATLHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAVRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV

Specific function: Unknown

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=743, Percent_Identity=25.9757738896366, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI71773480, Length=743, Percent_Identity=24.4952893674293, Blast_Score=130, Evalue=5e-30,
Organism=Escherichia coli, GI1786478, Length=732, Percent_Identity=98.7704918032787, Blast_Score=1484, Evalue=0.0,
Organism=Escherichia coli, GI1789230, Length=760, Percent_Identity=28.6842105263158, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789246, Length=807, Percent_Identity=25.4027261462206, Blast_Score=184, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17540638, Length=721, Percent_Identity=25.2427184466019, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32566215, Length=553, Percent_Identity=22.9656419529837, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=735, Percent_Identity=21.4965986394558, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647195, Length=743, Percent_Identity=24.2261103633917, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24647199, Length=719, Percent_Identity=23.0876216968011, Blast_Score=123, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24647197, Length=734, Percent_Identity=24.2506811989101, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17737937, Length=722, Percent_Identity=24.5152354570637, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24647193, Length=727, Percent_Identity=24.2090784044017, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24647201, Length=718, Percent_Identity=24.3732590529248, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 78054; Mature: 78054

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWYEEAPNAAYGYIVGSAIAK
CCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHH
GCLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLAGPTIEHYHQAIALVVAETF
HHHHHHCCCHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDKNVGDFDGAFTSAAVKIDATY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEE
TTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
CCCCCCCEEECCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPTIPNNTTHRPATLQHLRIGADQSGKIT
CCCCEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCEE
AISHESWSGNLPGGTPETAVQQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMA
EEECCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRRFSRRQLIECLRTGADKFGWKQRNAT
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
PGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
CCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCEEEHHHHH
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPGQ
HHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SQFADGKITNGTRSATLHEATAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATG
CCCCCCCCCCCCCCCEEEECCCCCEEEHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCH
EVRVRRMLAVCAAVRILNPKTARSQVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
VPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCC
LDKLLDKLPDVV
HHHHHHHCCCCC
>Mature Secondary Structure
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWYEEAPNAAYGYIVGSAIAK
CCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHH
GCLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLAGPTIEHYHQAIALVVAETF
HHHHHHCCCHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDKNVGDFDGAFTSAAVKIDATY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEE
TTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
CCCCCCCEEECCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPTIPNNTTHRPATLQHLRIGADQSGKIT
CCCCEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCEE
AISHESWSGNLPGGTPETAVQQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMA
EEECCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRRFSRRQLIECLRTGADKFGWKQRNAT
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
PGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
CCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCEEEHHHHH
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPGQ
HHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SQFADGKITNGTRSATLHEATAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATG
CCCCCCCCCCCCCCCEEEECCCCCEEEHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCH
EVRVRRMLAVCAAVRILNPKTARSQVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
VPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCC
LDKLLDKLPDVV
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]