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The map label for this gene is hopD [H]

Identifier: 218702084

GI number: 218702084

Start: 3968103

End: 3968492

Strand: Direct

Name: hopD [H]

Synonym: ECIAI39_3816

Alternate gene names: 218702084

Gene position: 3968103-3968492 (Clockwise)

Preceding gene: 218702053

Following gene: 218702096

Centisome position: 77.32

GC content: 50.26

Gene sequence:

>390_bases
TTGTTACCTGACAGATTTACCTGCCCGTTACTCTGGTCAGGTCTTTTGTTCTATCAGGTTTGTAATCCTGACGGTTTAGC
CGATGCGTTATGGGGGGCGATTATTGGTTACGGCACATTCGCTGTCATTTACTGGGGGTATCGCATACTGCGTCATAAAG
AAGGATTAGGCTATGGTGATGTGAAGTTTCTCGCCGCCCTTGGTGCCTGGCATACATGGACCTTCTTGCCACGACTGGTT
TTCCTTGCTGCCTCATTCGCTTGCGGAGCCGTAGTTATTGGTCTGCTCATGAGAGGAAAAGAGTCATTAAAAAACCCGCT
GCCGTTTGGGCCATTTCTGGCGGCTGCGGGTTTCGTTGTAGGCTGGGATAGTTTGCTGGCAGGCCGTTAA

Upstream 100 bases:

>100_bases
TCCAATTACAGAGGATGTTTTATGGACGCTACCCTTCCCTTTCTGATTTTGTACGCTTGTTTATCAGCCCTACTTTTTTT
TCTGGGATGCAAAGCATGGC

Downstream 100 bases:

>100_bases
TCTTTAACTTTTATTTGTGATTGCAGGTAATTTTGTAAACCGATTTTACCGATGAGATCCAGCTCAGTTTCGAGCCAGTC
AATATGACCTTCTTCATCGG

Product: putative bifunctional prepilin peptidase HopD: leader peptidase; methyl transferase (General Secretory Pathway)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MLPDRFTCPLLWSGLLFYQVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFLPRLV
FLAASFACGAVVIGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR

Sequences:

>Translated_129_residues
MLPDRFTCPLLWSGLLFYQVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFLPRLV
FLAASFACGAVVIGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR
>Mature_129_residues
MLPDRFTCPLLWSGLLFYQVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFLPRLV
FLAASFACGAVVIGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR

Specific function: Cleaves Type-4 Fimbrial Leader Sequence And Methylates The N-Terminal (Generally Phe) Residue (By Similarity). [C]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI1789732, Length=119, Percent_Identity=41.1764705882353, Blast_Score=73, Evalue=7e-15,
Organism=Escherichia coli, GI87082194, Length=118, Percent_Identity=38.135593220339, Blast_Score=66, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF01478 Peptidase_A24 [H]

EC number: 3.4.23.43

Molecular weight: Translated: 14113; Mature: 14113

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDRFTCPLLWSGLLFYQVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGD
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VKFLAALGAWHTWTFLPRLVFLAASFACGAVVIGLLMRGKESLKNPLPFGPFLAAAGFVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHH
GWDSLLAGR
HHHHHHCCC
>Mature Secondary Structure
MLPDRFTCPLLWSGLLFYQVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGD
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VKFLAALGAWHTWTFLPRLVFLAASFACGAVVIGLLMRGKESLKNPLPFGPFLAAAGFVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHH
GWDSLLAGR
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA