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The map label for this gene is yfhH

Identifier: 218701074

GI number: 218701074

Start: 2873278

End: 2874126

Strand: Direct

Name: yfhH

Synonym: ECIAI39_2765

Alternate gene names: 218701074

Gene position: 2873278-2874126 (Clockwise)

Preceding gene: 218701071

Following gene: 218701075

Centisome position: 55.99

GC content: 52.06

Gene sequence:

>849_bases
ATGAACGGCTTACTTCGTATCCGTCAGCGTTACCAGGGGCTTGCCCAGAGCGATAAAAAACTGGCGGATTATCTGCTGCT
ACAACCTGATACGGCGCGCCATTTAAGCTCTCAGCAACTGGCCAACGAAGCCGGAGTCAGTCAGTCCAGCGTCGTGAAGT
TCGCGCAAAAACTCGGCTATAAAGGTTTTCCGGCACTAAAGTTGGCGTTGAGTGAAGCGCTGGCAAGCCAGCCGGAATCT
CCCTCCGTGCCCATTCATAACCAAATCCGCGGTGATGATCCGTTACGGCTGGTCGGCGAAAAACTGATTAAAGAAAATAC
TGCCGCTATGTACGCAACGTTAAACGTTAATAGTGAAGAGAAACTGCATGAATGCGTGGCAATGTTGCGCTCTGCGCGGC
GGATAATTCTGACCGGTATTGGCGCTTCGGGTCTGGTGGCGCAAAACTTTGCCTGGAAGCTGATGAAGATTGGCTTCAAT
GCTGCCGCAGTGCGCGATATGCATGCGCTACTCGCTACAGTACAGGCGTCGTCCCCTGACGATCTGTTATTAGCCATTTC
CTACACCGGTGTACGACGCGAGTTAAACCTGGCGGCAGATGAGATGCTGCGAGTGGGCGGAAAAGTGCTGGCGATTACCG
GCTTTACTCCCAATGCCCTGCAACAGCGTGCTTCTCATTGCCTGTATACCATTGCCGAAGAACAAGCGACAAACAGTGCT
TCAATCTCTGCTTGTCACGCGCAGGGAATGTTAACGGATTTGCTGTTCATTGCGCTGATTCAGCAGGATCTGGAACTGGC
ACCAGAACGTATTCGTCATAGCGAAGCGCTGGTGAAAAAACTGGTCTGA

Upstream 100 bases:

>100_bases
AATTTTTAATTCATGGCAATTAGCGGCGATGGAATATAAAATTCACTCGCGTGTGTCTCATATTGCCTGTTGTCGCCACT
ATTTCATCGCGAGGAAAGAT

Downstream 100 bases:

>100_bases
GTAAAGAATGCGCGTATAATGCCCGCCCGGTTTGTGTTGTTTTGAGAGTTTCCTTATGGCGCTGTTAATCACTAAAAAAT
GCATCAATTGTGATATGTGT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGYKGFPALKLALSEALASQPES
PSVPIHNQIRGDDPLRLVGEKLIKENTAAMYATLNVNSEEKLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPNALQQRASHCLYTIAEEQATNSA
SISACHAQGMLTDLLFIALIQQDLELAPERIRHSEALVKKLV

Sequences:

>Translated_282_residues
MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGYKGFPALKLALSEALASQPES
PSVPIHNQIRGDDPLRLVGEKLIKENTAAMYATLNVNSEEKLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPNALQQRASHCLYTIAEEQATNSA
SISACHAQGMLTDLLFIALIQQDLELAPERIRHSEALVKKLV
>Mature_282_residues
MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGYKGFPALKLALSEALASQPES
PSVPIHNQIRGDDPLRLVGEKLIKENTAAMYATLNVNSEEKLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPNALQQRASHCLYTIAEEQATNSA
SISACHAQGMLTDLLFIALIQQDLELAPERIRHSEALVKKLV

Specific function: Unknown

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082130, Length=282, Percent_Identity=99.645390070922, Blast_Score=573, Evalue=1e-165,
Organism=Escherichia coli, GI1788767, Length=272, Percent_Identity=35.6617647058824, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788159, Length=195, Percent_Identity=27.1794871794872, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082369, Length=274, Percent_Identity=21.5328467153285, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30678; Mature: 30678

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGY
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKLIKENTAAMYATLNVNSEE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHH
KLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFNAAAVRDMHALLATVQASSPD
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
DLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPNALQQRASHCLYTIAEEQATNSA
CEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
SISACHAQGMLTDLLFIALIQQDLELAPERIRHSEALVKKLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGY
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKLIKENTAAMYATLNVNSEE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHH
KLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFNAAAVRDMHALLATVQASSPD
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
DLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPNALQQRASHCLYTIAEEQATNSA
CEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
SISACHAQGMLTDLLFIALIQQDLELAPERIRHSEALVKKLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 1602968; 7984428 [H]