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The map label for this gene is yfhR

Identifier: 218701044

GI number: 218701044

Start: 2837561

End: 2838442

Strand: Direct

Name: yfhR

Synonym: ECIAI39_2735

Alternate gene names: 218701044

Gene position: 2837561-2838442 (Clockwise)

Preceding gene: 218701043

Following gene: 218701045

Centisome position: 55.29

GC content: 49.43

Gene sequence:

>882_bases
ATGATAAAGAAGTCGCAAGGAAAGGTTATGGCGCTGCCAGTGAACAAACGCGTTCTCAAAATTCTGTTTATTCTCTTTGT
TGTTGCCTTCTGCGTTTATTTAGTGCCGCGCGTCGCCATCAATTTCTTCTATTATCCTGACGACAAAATTTACGGTCCCG
ACCCCTGGTCGGCGGAATCCGTCGAATTTACGGCTAAGGACGGTACTCGTCTGCAAGGCTGGTTTATTCCTTCTTCGACG
GGCCCTGCTGACAACGCTATCGCAACCATCATTCATGCTCACGGCAATGCCGGAAATATGTCCGCCCACTGGCCGCTGGT
CAGTTGGTTACCCGAGCGTAATTTCAACGTTTTTATGTTTGATTATCGCGGATTCGGTAAATCAAAAGGAAAACCTTCTC
AGGCAGGGTTATTAGACGATACGCAAAGTGCCATCAATGTGGCGCGCCATCGCAGTGATGTAAACCCACAACGGCTGGTG
CTGTTCGGGCAGAGTATTGGCGGGGCGAATATTCTTGATGTTATTGGTCAGGGTGATCGTGAAGGCATACGTGCGGTGAT
CCTCGACTCCACCTTTGCCTCTTATGCGACCATCGCCAACCAGATGATCCCCGGCAGTGGCTACTTACTTGATGAGAGTT
ACAGCGGCGAAAATTACATCGCCAGCGTCAGCCCGATCCCGCTTTTACTCATTCACGGTAAAGCTGATCACGTTATCCCA
TGGCAGCACAGCGAAAAGTTGTATAGCCTGGCAAAAGAGCCAAAACGGTTGATCCTAATCCCGGATGGCGAACACATTGA
TGCTTTTTCCGATCGTCACGGCGATGTTTATCGCGAACAGATGGTGGATTTTATCCTTAGCGCGTTGAATCCGCAGAACT
AA

Upstream 100 bases:

>100_bases
ATCACTCACCCGCCCTCGCCTTTCAGGCGCTATTCCGAAATACTTCCTCACCGCTTTACTTTCTTTCGTCACTCTCCCAC
CATCTTTCCCCGATTAATGG

Downstream 100 bases:

>100_bases
CCCATGATCGCTAGCACGATAATCATTCACAAAACCACCTTAAGACATGCTAACCCACTGGTCAGAACAGTTTAAGATGA
GAAAAATTCTGTGACGCTTG

Product: putative peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MIKKSQGKVMALPVNKRVLKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLQGWFIPSST
GPADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGKPSQAGLLDDTQSAINVARHRSDVNPQRLV
LFGQSIGGANILDVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIP
WQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN

Sequences:

>Translated_293_residues
MIKKSQGKVMALPVNKRVLKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLQGWFIPSST
GPADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGKPSQAGLLDDTQSAINVARHRSDVNPQRLV
LFGQSIGGANILDVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIP
WQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN
>Mature_293_residues
MIKKSQGKVMALPVNKRVLKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLQGWFIPSST
GPADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGKPSQAGLLDDTQSAINVARHRSDVNPQRLV
LFGQSIGGANILDVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIP
WQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine esterase family [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=265, Percent_Identity=29.0566037735849, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI71051602, Length=227, Percent_Identity=29.0748898678414, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI71051600, Length=227, Percent_Identity=29.0748898678414, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI151301175, Length=207, Percent_Identity=31.4009661835749, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI194306564, Length=235, Percent_Identity=28.936170212766, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI194306562, Length=214, Percent_Identity=29.9065420560748, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI32451492, Length=198, Percent_Identity=28.2828282828283, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI32528310, Length=198, Percent_Identity=28.2828282828283, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI109689718, Length=181, Percent_Identity=29.2817679558011, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI24308097, Length=219, Percent_Identity=28.310502283105, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI226510965, Length=284, Percent_Identity=98.5915492957747, Blast_Score=577, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988362, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6324009, Length=233, Percent_Identity=30.0429184549356, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17137566, Length=249, Percent_Identity=30.9236947791165, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281362521, Length=236, Percent_Identity=26.6949152542373, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281362519, Length=236, Percent_Identity=26.6949152542373, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571878, Length=236, Percent_Identity=26.6949152542373, Blast_Score=88, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 32504; Mature: 32504

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKSQGKVMALPVNKRVLKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAES
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCC
VEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMF
EEEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHEECCCCCCEEEEE
DYRGFGKSKGKPSQAGLLDDTQSAINVARHRSDVNPQRLVLFGQSIGGANILDVIGQGDR
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCC
EGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIP
CCCEEEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEECCCCCCCC
WQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN
CCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKKSQGKVMALPVNKRVLKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAES
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCC
VEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMF
EEEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHEECCCCCCEEEEE
DYRGFGKSKGKPSQAGLLDDTQSAINVARHRSDVNPQRLVLFGQSIGGANILDVIGQGDR
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCC
EGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIP
CCCEEEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEECCCCCCCC
WQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN
CCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]