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The map label for this gene is rtn

Identifier: 218700648

GI number: 218700648

Start: 2384881

End: 2386437

Strand: Direct

Name: rtn

Synonym: ECIAI39_2317

Alternate gene names: 218700648

Gene position: 2384881-2386437 (Clockwise)

Preceding gene: 218700647

Following gene: 218700649

Centisome position: 46.47

GC content: 49.84

Gene sequence:

>1557_bases
ATGTTTATACGCGCTCCCAATTCTGGACGTAAGCTCCTGCTTACCTGCATTGTTGCAGGCGTGATGATTGCGATACTGGT
GAGCTGCCTTCAGTTTTTAGTGGCCTGGCATAAGCACGAAGTCAAATACGACACACTGATTACCGACGTACAAAAGTATC
TCGATACCTATTTTGCCGACCTGAAATCCACTACTGACCGGCTCCAGCCGCTGACCTTAGATACCTGCCAGCAGGCTAAC
CCCGAACTGACCGCTCGCGCGGCGTTTAGCATGAATGTCCGTACGTTTGTGCTGGTGAAAGATAAAAAAACATTCTGTTC
ATCTGCGACTGGTGAGATGGACATTCCACTAAAAGAATTGATTCCGGCGCTCGACATTAATAAAAATGTCGATATGGCGA
TCTTACCCGGTACGCCGATGGTGCCGAACAAACCCGCAATCGTCATCTGGTATCGCAACCCTTTGCTGAAAAATAGCGGC
GTCTTTGCCGCTCTGAATCTCAATCTGACGCCTTCACTCTTCTATAGCTCACGGCAGGAAGATTACGATGGTGTCGCCCT
CATTATTGGTAATACTGCTCTATCTACCTTTTCGTCACGTTTGATGAATGTTAATGAATTAACCGACATGCCGGTCCGTG
AAACTAAAATTGCGGGCATTCCTCTGACCGTTCGGCTTTATGCGGATGACTGGACATGGAACGATGTGTGGTACGCATTT
TTACTGGGTGGCATGAGTGGAACTTTCGTTGGACTTCTCTGCTATTACCTGATGAGTGTGCGTATGCGCCCAGGCAGAGA
AATCATGACCGCCATCAAGCGCGAACAATTTTACGTGGTATATCAACCGGTGGTTGATACACAAGCTTTGCGGGTAACGG
GCCTGGAAGTACTGCTACGCTGGCGGCATCCAGTAGCAGGAGAAATCCCCCCGGATGCCTTCATTAACTTTGCCGAAGCG
CAAAAGATGATTGTGCCACTGACTCAGCACCTGTTTGAGTTGATTGCCCGCGATGCCGCAGAATTAGAAAAAGTACTGCC
GGTAGGCGTCAAATTTGGCATTAACATTGCGCCGGCCCACTTGCACAGCGAAAGCTTTAAAGCGGATATCCAGAAACTAC
TCACTTCCCTGCCCGCACACCATTTCCAGATTGTGCTGGAAATTACCGAGCGCGATATGCTGAAAGAGCGAGAAGCCACA
CAACTCTTCGCCTGGCTGCATTCGGTCGGCGTAGAAATTGCTATTGATGACTTCGGCACCGGGCACAGCGCGCTTATCTA
TCTTGAGCGTTTTACGCTCGATTATCTGAAAATTGATCGTGGATTTATCAACGCCATCGGTACGGAAACGATCACTTCAC
CCGTACTTGACGCGGTGCTGACGCTGGCGAAACGCCTCAATATGCTGACGGTTGCTGAAGGGGTCGAAACGCCAGAACAG
GCACGATGGCTAAGCGAACGCGGCGTTAATTTCATGCAAGGCTACTGGATTAGTCGCCCGTTACCGCTGGACGATTTTGT
TCGCTGGCTGAAGAAACCGTATACGCCGCAGTGGTAA

Upstream 100 bases:

>100_bases
TTCATCAGAGAAAATGATGTTTCCGCGTCTTGATCCAGGCTATAGTCCGGTCATTGTTATCTTTTAAATGTTGTCGTAAT
TTCAGGAAATTAACGGAATC

Downstream 100 bases:

>100_bases
GGTGTGCTTACGTCCCTTATTATTCATAGTGAAAGCATGCCGGATTGCGGCTAATGATGAGTAAAAGGAAATCCGTTGCA
GATGATTGTGCGCATACTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLKELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQFYVVYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAEA
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPAHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEREAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW

Sequences:

>Translated_518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLKELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQFYVVYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAEA
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPAHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEREAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW
>Mature_518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLKELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQFYVVYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAEA
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPAHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEREAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=518, Percent_Identity=98.6486486486486, Blast_Score=1056, Evalue=0.0,
Organism=Escherichia coli, GI87081980, Length=518, Percent_Identity=28.957528957529, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=39.2857142857143, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=36.4372469635627, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=30.6772908366534, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI87081743, Length=271, Percent_Identity=30.2583025830258, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787541, Length=246, Percent_Identity=30.4878048780488, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081921, Length=269, Percent_Identity=29.7397769516729, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI226510982, Length=253, Percent_Identity=31.2252964426877, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=28.2786885245902, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=29.6296296296296, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787055, Length=251, Percent_Identity=29.4820717131474, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787410, Length=226, Percent_Identity=24.7787610619469, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58587; Mature: 58587

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFAD
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLKEL
HHHHHHHCCCCCHHHHHCCCCCEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHH
IPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQE
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCC
DYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
CCCCEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHH
LLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQFYVVYQPVVDTQALRVTGLEVLLR
HHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHH
WRHPVAGEIPPDAFINFAEAQKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPAH
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEHHH
LHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEREATQLFAWLHSVGVEIAIDDFGT
HCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
CCCEEEEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHH
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFAD
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLKEL
HHHHHHHCCCCCHHHHHCCCCCEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHH
IPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQE
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCC
DYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
CCCCEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHH
LLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQFYVVYQPVVDTQALRVTGLEVLLR
HHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHH
WRHPVAGEIPPDAFINFAEAQKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPAH
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEHHH
LHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEREATQLFAWLHSVGVEIAIDDFGT
HCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
CCCEEEEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHH
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]