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The map label for this gene is yeiQ

Identifier: 218700644

GI number: 218700644

Start: 2380400

End: 2381866

Strand: Direct

Name: yeiQ

Synonym: ECIAI39_2313

Alternate gene names: 218700644

Gene position: 2380400-2381866 (Clockwise)

Preceding gene: 218700643

Following gene: 218700645

Centisome position: 46.38

GC content: 52.15

Gene sequence:

>1467_bases
ATGAATACAATCGCCTCCGTTACGCTCCCGCATCATGTACACGCTCCACGCTACGATCGCCAGCAGTTGCAATCACGTAT
CGTTCATTTTGGCTTTGGAGCCTTTCACCGCGCTCATCAGGCGTTACTGACCGATCGTGTGCTGAATGCCCAGGGCGGCG
ACTGGGGGATCTGTGAGATCAGCTTGTTCAGCGGCGATCAACTGATGAGCCAGCTCCGCGCACAGAACCATTTATATACC
GTGCTGGAGAAAGGTGCGGACGGCAATCAGGCGATAATTGTCGGTGCCGTTCACGACTGCCTGAATGCAAAACTGGATTC
CTTAGCGGCAATTATTGAGAAATTTTGCGAGCCACAGGTGGCAATTGTTTCCCTGACGATTACCGAAAAAGGCTATTGTA
TTGACCCGGCCACCGGTGCACTCGACACCAGCAATCCGCGGATTATTCACGATCTTCAAAATCCTGAAGAACCTCACTCC
GCGCCGGGTATTCTCGTCGAAGCACTGAAACGACGCCGTGAACGCGGCCTTGCACCGTTTACCGTACTCTCCTGCGACAA
TATTCCCGACAATGGCCATGTGGTGAAAAACGCGGTGCTGGGGATGGCGGAAAAACGTTCACCAGAACTCGCCGGGTGGA
TAAAAGAACACGTCAGTTTTCCGGGAACCATGGTCGACCGTATTGTTCCGGCAGCAACCGACGAATCACTGGCGGAAATC
AGCCAGCATCTGGGGGTGAATGATCCCTGTGCGATTAGCTGCGAACCGTTTATCCAGTGGGTGGTGGAAGATAACTTCGT
CGCTGGGCGTCCTGCCTGGGAAGTCGCAGGTGTACAAATGGTGAATGATGTCCTGCCATGGGAAGAGATGAAACTGCGGA
TGCTTAATGGCAGCCACTCTTTTCTCGCTTATCTGGGTTACCTCTCAGGATTCGCCCATATCAGTGATTGCATGCAGGAT
CGCGCATTTCGCCATGCCGCCAGAACAATAATGCTGGATGAGCAAGCGCCGACACTGCGGATTAAAGATGTCGATTTAAC
ACAATATGCGGATAAGTTAATTGCACGTTTTGCTAACCCGGCGCTGAAACATAAGACCTGGCAAATCGCGATGGATGGCA
GCCAGAAATTACCGCAACGTATGCTGGCAGGTATTCGCATACATCTGGCGCGCGAAACGGACTGGTCGTTGCTGGCATTA
GGCGTTGCAGGCTGGATGCGTTACGTCAGCGGCGTTGATGATGCCGGAAATGCCATTGATGTTCGCGATCCGCTTAGCGA
TAAAATTTGCGAACTTGTTGCGGGCAGTAACAGTGAACAACGCGTAACCGCCCTGCTTTCTCTGCGTGAAGTTTTCGGTG
ATGATCTGCCAGATAACCCGCATTTTGTGCAGGCAATCGAACAAGCCTGGCAACAAATCGCACAATTCGGCGCGCATCAA
GCGCTATTAAACACCCTCAAAATTTAA

Upstream 100 bases:

>100_bases
CCTCACACTTCATCGCATTAACAATCCAGACCAATTTCAATTGCTGTCATATAACTTTACACTGTCATTGTTAATTAATC
GTTACTAAGACGTGACTCCT

Downstream 100 bases:

>100_bases
CGATTTCTGCGGTTAAAGCGGATGAAGCTCGCCTTCGTCCGCTCTCCCCTTCTCTTTTCTGCCTTTTTTAGCCAGGATTA
ACGCTCAGTTAACTTTTAAG

Product: putative sugar dehydrogenase, NAD-dependent

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQAIIVGAVHDCLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHS
APGILVEALKRRRERGLAPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTIMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLARETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKICELVAGSNSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIAQFGAHQ
ALLNTLKI

Sequences:

>Translated_488_residues
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQAIIVGAVHDCLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHS
APGILVEALKRRRERGLAPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTIMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLARETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKICELVAGSNSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIAQFGAHQ
ALLNTLKI
>Mature_488_residues
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQAIIVGAVHDCLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHS
APGILVEALKRRRERGLAPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTIMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLARETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKICELVAGSNSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIAQFGAHQ
ALLNTLKI

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=488, Percent_Identity=97.5409836065574, Blast_Score=987, Evalue=0.0,
Organism=Escherichia coli, GI1790779, Length=485, Percent_Identity=56.0824742268041, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI1787823, Length=464, Percent_Identity=55.3879310344828, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1790028, Length=232, Percent_Identity=28.8793103448276, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI48994885, Length=371, Percent_Identity=23.989218328841, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324401, Length=478, Percent_Identity=39.3305439330544, Blast_Score=361, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320765, Length=478, Percent_Identity=39.3305439330544, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 53918; Mature: 53918

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEI
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHDCLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHSAPGILVEALKRRRERGLAPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHH
FLAYLGYLSGFAHISDCMQDRAFRHAARTIMLDEQAPTLRIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHHHHHHHHCCH
ALKHKTWQIAMDGSQKLPQRMLAGIRIHLARETDWSLLALGVAGWMRYVSGVDDAGNAID
HHHCCEEEEEECCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKICELVAGSNSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIAQFGAHQ
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALLNTLKI
HHHHHHCC
>Mature Secondary Structure
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEI
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHDCLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHSAPGILVEALKRRRERGLAPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHH
FLAYLGYLSGFAHISDCMQDRAFRHAARTIMLDEQAPTLRIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHHHHHHHHCCH
ALKHKTWQIAMDGSQKLPQRMLAGIRIHLARETDWSLLALGVAGWMRYVSGVDDAGNAID
HHHCCEEEEEECCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKICELVAGSNSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIAQFGAHQ
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALLNTLKI
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]