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The map label for this gene is putA

Identifier: 218700475

GI number: 218700475

Start: 2184987

End: 2188949

Strand: Direct

Name: putA

Synonym: ECIAI39_2141

Alternate gene names: 218700475

Gene position: 2184987-2188949 (Clockwise)

Preceding gene: 218700469

Following gene: 218700477

Centisome position: 42.58

GC content: 56.4

Gene sequence:

>3963_bases
ATGGGAACCACCACCATGGGGGTTAAGCTGGACGACGCGACGCGTGAGCGTATTAAGTCTGCCGCGACACGTATCGATCG
CACGCCACACTGGTTAATTAAGCAGGCGATTTTTTCTTATCTTGAACAACTGGAAAACAGCGATACTCTGCCGGAGCTAC
CTGCGCTGCTTTCTGGCGCTGCCAATGAGAGCGATGAAGCACCGACTCCGGCAGAGGAACCACACCAGCCATTCCTCGAC
TTTGCCGAGCAAATTTTGCCCCAGTCGGTTTCCCGCGCCGCGATCACCGCGGCCTATCGCCGCCCGGAAACCGAAGCGGT
TTCTATGCTGCTGGAACAAGCCCGCCTGCCGCAACCAGTTGCTGAACAGGCGCATAAACTGGCGTATCAACTGGCCGATA
AACTGCGTAATCAAAAAAATGCCAGTGGTCGCGCAGGTATGGTCCAGGGGTTATTGCAGGAGTTTTCGCTGTCATCGCAG
GAAGGCGTGGCGCTGATGTGTCTGGCAGAAGCGTTGTTGCGTATTCCCGACAAAGCCACCCGGGACGCGTTAATTCGCGA
CAAAATCAGCAACGGTAACTGGCAGTCACACATTGGTCGTAGCCCGTCTTTGTTTGTTAATGCCGCCACCTGGGGGCTGC
TGTTTACCGGCAAACTGGTTTCCACCCATAACGAAGCCAGCCTCTCCCGCTCGCTGAACCGCATTATCGGTAAGAGCGGT
GAACCGCTGATCCGCAAAGGTGTGGATATGGCGATGCGCCTGATGGGAGAGCAGTTCGTCACTGGCGAAACCATCGCGGA
AGCGTTAGCCAATGCCCGCAAGCTGGAAGAGAAAGGTTTCCGTTACTCTTACGATATGCTGGGCGAAGCCGCGCTGACTG
CCGCAGATGCACAGGCGTATATGGTTTCCTATCAACAGGCGATTCACGCCATTGGTAAAGCGTCCAATGGTCGTGGCATC
TATGAAGGTCCAGGCATTTCAATCAAGCTGTCGGCGCTGCATCCGCGTTACAGCCGCGCCCAGTATGACCGGGTAATGGA
AGAGCTTTACCCACGTCTGAAATCACTCACCCTGCTGGCGCGTCAGTACGATATTGGTATTAACATCGATGCCGAAGAGG
CCGATCGTCTGGAGATCTCCCTCGATCTGCTGGAAAAACTCTGTTTCGAGCCGGAACTGGCAGGCTGGAACGGCATCGGT
TTTGTTATTCAGGCTTATCAAAAACGCTGCCCGTTGGTGATCGATTACCTGATTGATCTCGCCACCCGCAGCCGTCGCCG
TCTGATGATTCGCCTGGTGAAAGGCGCGTACTGGGATAGTGAAATCAAGCGTGCACAGATGGACGGCCTTGAAGGTTATC
CGGTTTATACCCGCAAGGTGTATACCGACGTTTCTTATCTTGCCTGTGCGAAAAAACTGCTGGCGGTGCCGAATTTAATC
TACCCGCAGTTCGCGACGCACAACGCCCATACGCTGGCGGCAATTTATCAACTGGCGGGTCAAAACTACTACCCGGGTCA
GTACGAGTTCCAGTGCCTGCATGGTATGGGCGAACCACTGTATGAGCAGGTCACCGGGAAAGTTGCCGACGGCAAACTTA
ACCGTCCGTGTCGTATTTATGCTCCGGTCGGTACACATGAAACGCTGCTGGCGTATCTGGTGCGCCGCCTGCTGGAAAAC
GGTGCTAACACCTCGTTTGTTAACCGTATTGCCGACACCTCTTTGCCACTGGATGAACTGGTCGCCGATCCAGTCACTGC
TGTAGAAAAACTGGCACAACAGGAAGGGCAAACTGGATTACCGCATCCGAAAATTCCCCTGCCGCGCGATCTTTACGGTC
ACGGGCGCGACAACTCGGCAGGGCTGGATCTCGCTAACGAACACCGTCTGGCCTCGCTCTCTTCAGCCCTGCTCAATAGT
GCACTGCAAAAATGGCAGGCCTTGCCAATGCTGGAACAACCGGTAGCGGCAGGTGAGATGTCGCCCGTTATTAACCCTGC
GGAACCGAAAGATATTGTGGGCTTTGTGCGTGAAGCCACGCCGCGTGAAGTAGAACAGGCGCTGGAAAGTGCGGTTAATA
ACGCGCCAATCTGGTTTGCCACGCCTCCGGCTGAACGCGCGGCAATTTTGCATCGCGCTGCCGTGCTAATGGAAAGCCAG
ATGCAGCAACTGATTGGTATTCTGGTGCGTGAAGCCGGAAAAACCTTCAGTAACGCCATTGCCGAAGTGCGCGAAGCGGT
CGATTTTCTCCACTACTATGCCGGACAGGTGCGGGATGATTTCGCTAACGAAACCCACCGTCCATTAGGGCCTGTGGTAT
GTATCAGTCCGTGGAACTTCCCGCTGGCGATTTTCACCGGACAGATCGCTGCCGCACTGGCGGCAGGTAACAGCGTGCTG
GCAAAACCGGCAGAACAAACGCCGCTGATTGCCGCGCAAGGGATCGCCATTTTGCTGGAAGCGGGTGTACCGCCAGGCGT
GGTGCAATTGCTGCCCGGTCGGGGTGAAACCGTGGGCGCGCAACTGACGGGTGATGATCGCGTGCGCGGGGTGATGTTTA
CCGGTTCAACCGAAGTCGCTACGTTACTGCAGCGCAATATCGCCAGCCGCCTGGACGCTCAGGGTCGCCCTATTCCGCTC
ATCGCGGAAACCGGCGGGATGAACGCGATGATTGTCGATTCTTCAGCACTGACCGAACAAGTCGTAATAGATGTGCTGGC
CTCGGCGTTCGACAGTGCAGGTCAGCGTTGTTCGGCACTGCGCGTGCTGTGCCTGCAAGATGAGATTGCCGACCACACGC
TGAAAATGCTGCGCGGCGCAATGGCCGAATGCCGGATGGGTAATCCGGGTCGCCTGACCACCGATATCGGTCCGGTGATT
GATAGCGAAGCGAAAGCCAATATCGAGCGTCATATTCAGACCATGCGTAGTAAAGGCCGTCAGGTGTTCCAGGCGGTGCG
GGAAAACAGCGAAGATGCCCGTGAATGGCAAAGCGGCACCTTTGTCGCTCCGACGCTGATCGAACTGGATGACTTTGCCG
AATTGCAAAAAGAGGTCTTTGGTCCGGTGCTGCATGTGGTGCGTTATAACCGTAACCAGCTGCCGGCGCTGATCGAGCAG
ATTAACGCTTCCGGTTATGGTCTGACGCTTGGCGTCCATACGCGCATTGATGAAACCATCGCCCAGGTCACTGGCTCGGC
GCATGTTGGTAACCTGTATGTTAACCGTAATATGGTGGGCGCAGTGGTTGGGGTGCAGCCGTTCGGCGGCGAAGGGTTGT
CTGGCACCGGGCCGAAAGCAGGCGGTCCACTCTATCTCTACCGTCTGCTGGCGAATCGCCCGGAAAGTGCGCTGGCGGTG
ACGCTCGCGCGTCAGGATGCAGAGTATCCGGTCGATGCGCAGTTGAAAGCCGCATTGACTCAGCCGCTAAATGCACTGCG
GGAATGGGCAGCAAATCGTCCAGAATTGCAGGCGTTATGTACGCAATATGGCGAGCTGGCGCAGGCAGGAACACAGCGAT
TGCTGCCAGGGCCGACGGGTGAACGCAACACCTGGACGCTGCTGCCGCGCGAGCGCGTGTTGTGTATTGCGGATGATGAA
CAGGATGCGCTGACTCAGCTCGCCGCCGTGCTGGCGGTGGGCAGCCAGGTACTGTGGCCGGATGACGCGCTGCATCGTCA
GTTAGTGAAGGCATTGCCATCGGCAGTCAGCGAACGTATTCAACTGGCGAAAGCGGAAAATATAACCGCTCAACCGTTTG
ATGCGGTGATCTTCCACGGTGATTCGGATCAGCTTCGCGCATTGTGTGAAGCCGTTGCCGCGCGGGATGGCGCAATTGTT
TCGGTGCAGGGTTTTGCCCGTGACGAAAGCAATATCCTTCTGGAACGGCTGTATATCGAACGTTCGCTGAGTGTGAATAC
CGCTGCCGCTGGCGGTAACGCCAGTTTAATGACGATCGGTTAA

Upstream 100 bases:

>100_bases
CTACGCAGGTCACATTCAACATGGTTGCACAAAGTTGCAACATCATGGATATTTCACGATAACGTTAAGTTGCACCTTTC
AGAACAACAGGAGTAATGGC

Downstream 100 bases:

>100_bases
ACAGGAAGCCGGAGGATGTTACAACCTCCTCCGGCATCTTTAACGTGGTCGAATCCCCTCAATAATTATCCGCTGCACGT
TTTCAACCGTTTGATTGAAA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1320; Mature: 1319

Protein sequence:

>1320_residues
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLD
FAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIG
FVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNS
ALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVL
AKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPL
IAETGGMNAMIVDSSALTEQVVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRSKGRQVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPALIEQ
INASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAV
TLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDE
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIV
SVQGFARDESNILLERLYIERSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1320_residues
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLD
FAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIG
FVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNS
ALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVL
AKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPL
IAETGGMNAMIVDSSALTEQVVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRSKGRQVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPALIEQ
INASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAV
TLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDE
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIV
SVQGFARDESNILLERLYIERSLSVNTAAAGGNASLMTIG
>Mature_1319_residues
GTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDF
AEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQE
GVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGE
PLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIY
EGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGF
VIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIY
PQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENG
ANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSA
LQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQM
QQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLA
KPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLI
AETGGMNAMIVDSSALTEQVVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVID
SEAKANIERHIQTMRSKGRQVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPALIEQI
NASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVT
LARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQ
DALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVS
VQGFARDESNILLERLYIERSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=466, Percent_Identity=30.9012875536481, Blast_Score=180, Evalue=1e-44,
Organism=Homo sapiens, GI25777724, Length=468, Percent_Identity=29.9145299145299, Blast_Score=179, Evalue=2e-44,
Organism=Homo sapiens, GI25777736, Length=522, Percent_Identity=29.6934865900383, Blast_Score=178, Evalue=4e-44,
Organism=Homo sapiens, GI25777734, Length=522, Percent_Identity=29.6934865900383, Blast_Score=178, Evalue=4e-44,
Organism=Homo sapiens, GI25777730, Length=489, Percent_Identity=29.8568507157464, Blast_Score=177, Evalue=6e-44,
Organism=Homo sapiens, GI153266822, Length=463, Percent_Identity=28.7257019438445, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI238859541, Length=446, Percent_Identity=31.1659192825112, Blast_Score=173, Evalue=9e-43,
Organism=Homo sapiens, GI25777728, Length=414, Percent_Identity=30.6763285024155, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=29.5508274231678, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI25777732, Length=458, Percent_Identity=28.82096069869, Blast_Score=160, Evalue=7e-39,
Organism=Homo sapiens, GI12007648, Length=432, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI238814322, Length=422, Percent_Identity=26.7772511848341, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI4507229, Length=488, Percent_Identity=29.3032786885246, Blast_Score=150, Evalue=1e-35,
Organism=Homo sapiens, GI25777721, Length=501, Percent_Identity=29.1417165668663, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI310128103, Length=543, Percent_Identity=27.0718232044199, Blast_Score=140, Evalue=8e-33,
Organism=Homo sapiens, GI310128093, Length=543, Percent_Identity=26.7034990791897, Blast_Score=140, Evalue=9e-33,
Organism=Homo sapiens, GI188035924, Length=524, Percent_Identity=27.4809160305344, Blast_Score=140, Evalue=9e-33,
Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=26.3498920086393, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777726, Length=466, Percent_Identity=25.9656652360515, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI310128091, Length=391, Percent_Identity=28.9002557544757, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI25952152, Length=432, Percent_Identity=27.3148148148148, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=25.8823529411765, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI310128087, Length=362, Percent_Identity=28.4530386740331, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI206597441, Length=409, Percent_Identity=25.6723716381418, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI206597439, Length=409, Percent_Identity=25.6723716381418, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI22907049, Length=409, Percent_Identity=25.6723716381418, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI71773324, Length=397, Percent_Identity=26.7002518891688, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI4502043, Length=341, Percent_Identity=26.9794721407625, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI238814371, Length=341, Percent_Identity=26.9794721407625, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI310128089, Length=330, Percent_Identity=26.969696969697, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128095, Length=317, Percent_Identity=27.7602523659306, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI73695881, Length=343, Percent_Identity=26.2390670553936, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI73695879, Length=343, Percent_Identity=26.2390670553936, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI310128101, Length=309, Percent_Identity=26.8608414239482, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128099, Length=297, Percent_Identity=27.6094276094276, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128097, Length=262, Percent_Identity=28.2442748091603, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI4557303, Length=383, Percent_Identity=25.8485639686684, Blast_Score=77, Evalue=2e-13,
Organism=Homo sapiens, GI73466520, Length=383, Percent_Identity=25.8485639686684, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI301500698, Length=283, Percent_Identity=25.0883392226148, Blast_Score=72, Evalue=5e-12,
Organism=Homo sapiens, GI223972651, Length=423, Percent_Identity=26.7139479905437, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1787250, Length=1320, Percent_Identity=99.3939393939394, Blast_Score=2685, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=466, Percent_Identity=30.68669527897, Blast_Score=177, Evalue=4e-45,
Organism=Escherichia coli, GI1787715, Length=455, Percent_Identity=32.0879120879121, Blast_Score=170, Evalue=6e-43,
Organism=Escherichia coli, GI1788042, Length=438, Percent_Identity=32.1917808219178, Blast_Score=165, Evalue=2e-41,
Organism=Escherichia coli, GI1787684, Length=461, Percent_Identity=29.0672451193059, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1787558, Length=416, Percent_Identity=30.2884615384615, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786504, Length=460, Percent_Identity=28.4782608695652, Blast_Score=151, Evalue=3e-37,
Organism=Escherichia coli, GI87081896, Length=468, Percent_Identity=29.0598290598291, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI87082295, Length=443, Percent_Identity=28.4424379232506, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI87081926, Length=448, Percent_Identity=27.0089285714286, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1787653, Length=404, Percent_Identity=22.2772277227723, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144435, Length=465, Percent_Identity=30.5376344086021, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17534447, Length=489, Percent_Identity=28.8343558282209, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=462, Percent_Identity=30.0865800865801, Blast_Score=166, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI115534176, Length=480, Percent_Identity=29.5833333333333, Blast_Score=164, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI133930964, Length=471, Percent_Identity=28.8747346072187, Blast_Score=163, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=30.8252427184466, Blast_Score=162, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=366, Percent_Identity=31.4207650273224, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=28.1030444964871, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25143874, Length=461, Percent_Identity=27.765726681128, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25143876, Length=461, Percent_Identity=27.765726681128, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17534119, Length=463, Percent_Identity=27.2138228941685, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=451, Percent_Identity=25.9423503325942, Blast_Score=132, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=415, Percent_Identity=26.9879518072289, Blast_Score=123, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=460, Percent_Identity=25.6521739130435, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=417, Percent_Identity=25.4196642685851, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=27.4834437086093, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=340, Percent_Identity=25.8823529411765, Blast_Score=88, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=390, Percent_Identity=23.0769230769231, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566756, Length=386, Percent_Identity=23.0569948186528, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25146394, Length=386, Percent_Identity=23.0569948186528, Blast_Score=82, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321826, Length=541, Percent_Identity=29.3900184842884, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6325196, Length=466, Percent_Identity=30.68669527897, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=461, Percent_Identity=27.5488069414317, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320917, Length=455, Percent_Identity=28.7912087912088, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=476, Percent_Identity=30.0420168067227, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=29.0526315789474, Blast_Score=155, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6319478, Length=466, Percent_Identity=30.0429184549356, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=374, Percent_Identity=26.7379679144385, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129399, Length=462, Percent_Identity=30.3030303030303, Blast_Score=172, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24650465, Length=461, Percent_Identity=27.765726681128, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24668425, Length=475, Percent_Identity=28.2105263157895, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24668417, Length=475, Percent_Identity=28.2105263157895, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24668413, Length=475, Percent_Identity=28.2105263157895, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI281362580, Length=452, Percent_Identity=28.0973451327434, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI62472918, Length=452, Percent_Identity=28.0973451327434, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI62472926, Length=452, Percent_Identity=28.0973451327434, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI62472936, Length=452, Percent_Identity=28.0973451327434, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21356737, Length=452, Percent_Identity=28.0973451327434, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24585660, Length=462, Percent_Identity=26.1904761904762, Blast_Score=155, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24666674, Length=451, Percent_Identity=29.7117516629712, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28571802, Length=452, Percent_Identity=28.3185840707965, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571800, Length=452, Percent_Identity=28.3185840707965, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571806, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571798, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571796, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571794, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28574525, Length=498, Percent_Identity=26.1044176706827, Blast_Score=135, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24638878, Length=401, Percent_Identity=26.9326683291771, Blast_Score=102, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24638876, Length=401, Percent_Identity=26.9326683291771, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281360299, Length=341, Percent_Identity=28.1524926686217, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360297, Length=341, Percent_Identity=28.1524926686217, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360295, Length=341, Percent_Identity=28.1524926686217, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24586250, Length=341, Percent_Identity=28.1524926686217, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360301, Length=341, Percent_Identity=28.1524926686217, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45552499, Length=338, Percent_Identity=26.6272189349112, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360303, Length=341, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 143801; Mature: 143670

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGA
CCCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
ANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
AEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKAT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHH
RDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
HHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHEECHHHHCCCHHHHHHHHHHHHCCCC
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAY
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
MVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLA
HHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDL
HHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
ATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHH
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIY
CCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEE
APVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGL
ECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCC
PHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEM
CCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
SPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNF
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
PLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCEEEEECCCCCCHHEECCCCCCEECE
QLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQ
EECCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCHHHHHH
VVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
DSEAKANIERHIQTMRSKGRQVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
GPVLHVVRYNRNQLPALIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVG
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCEECEEEECCCCEE
AVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALT
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHH
QPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
DSDQLRALCEAVAARDGAIVSVQGFARDESNILLERLYIERSLSVNTAAAGGNASLMTIG
CHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEC
>Mature Secondary Structure 
GTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGA
CCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
ANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
AEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKAT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHH
RDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
HHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHEECHHHHCCCHHHHHHHHHHHHCCCC
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAY
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
MVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLA
HHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDL
HHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
ATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHH
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIY
CCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEE
APVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGL
ECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCC
PHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEM
CCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
SPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNF
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
PLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCEEEEECCCCCCHHEECCCCCCEECE
QLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQ
EECCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCHHHHHH
VVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
DSEAKANIERHIQTMRSKGRQVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
GPVLHVVRYNRNQLPALIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVG
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCEECEEEECCCCEE
AVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALT
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHH
QPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
DSDQLRALCEAVAARDGAIVSVQGFARDESNILLERLYIERSLSVNTAAAGGNASLMTIG
CHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]