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The map label for this gene is flgM

Identifier: 218700426

GI number: 218700426

Start: 2137344

End: 2137634

Strand: Direct

Name: flgM

Synonym: ECIAI39_2092

Alternate gene names: 218700426

Gene position: 2137344-2137634 (Clockwise)

Preceding gene: 218700425

Following gene: 218700427

Centisome position: 41.65

GC content: 53.26

Gene sequence:

>291_bases
ATGAGTATTGATCGCACGCCTCTGAAGCCCGTAAGCACCGTTCAACCGCGCGAAACCACTGACGCGCCGGTAACGAACAC
CCGGGCGGCAAAAACAACCGCCTCCACCAGCACCAGTGTGACGTTAAGCGACGCGCAAGCAAAACTGATGCAACCCGGCA
GCAGTGATATCAATCTTGAACGTGTCGAAGCGTTAAAACTGGCGATTCGTAACGGTGAACTAAAAATGGACACCGGCAAA
ATTGCCGATGCGCTGATCAACGAAGCGCAGCAAGACTTGCAGAGTAACTGA

Upstream 100 bases:

>100_bases
TGGGAATATTCTTATAAACCTGTAAGCTGTTAAAGATTACCCGTCCCTTGCCGATAAATAAGCAACACATGATAAAAGCG
CCCTCAATGAGGAATAAACC

Downstream 100 bases:

>100_bases
TCGTATGACGCGTCTTGCAGAGATCCTCGACCAGATGTCCGCTGTGCTTAACGATCTCAAAACGGTAATGGATCAAGAAC
AGCAACATCTCTCTATGGGG

Product: anti-sigma28 factor FlgM

Products: NA

Alternate protein names: Anti-sigma-28 factor [H]

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MSIDRTPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGK
IADALINEAQQDLQSN

Sequences:

>Translated_96_residues
MSIDRTPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGK
IADALINEAQQDLQSN
>Mature_95_residues
SIDRTPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKI
ADALINEAQQDLQSN

Specific function: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of

COG id: COG2747

COG function: function code KNU; Negative regulator of flagellin synthesis (anti-sigma28 factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flgM family [H]

Homologues:

Organism=Escherichia coli, GI1787311, Length=97, Percent_Identity=97.9381443298969, Blast_Score=159, Evalue=2e-41,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007412 [H]

Pfam domain/function: PF04316 FlgM [H]

EC number: NA

Molecular weight: Translated: 10268; Mature: 10136

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDRTPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCHH
RVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN
HHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIDRTPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCHH
RVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN
HHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9095196 [H]