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The map label for this gene is nhoA

Identifier: 218700093

GI number: 218700093

Start: 1809002

End: 1809847

Strand: Direct

Name: nhoA

Synonym: ECIAI39_1725

Alternate gene names: 218700093

Gene position: 1809002-1809847 (Clockwise)

Preceding gene: 218700091

Following gene: 218700104

Centisome position: 35.25

GC content: 50.47

Gene sequence:

>846_bases
ATGACGCCCATTCTGAATCACTATTTTGCCCGTATTAACTGGTTGGGAGCTGCTGCGGCCAATATTGATACGCTGCGTGC
ATTGCACCTGAAACACAATTGCACCATTCCGTTTGAAAATCTCGACGTTTTGCTGCCGAGGGAAATACAGCTTGATGATC
AATCGCTGGAAGAGAAACTGGTGATAGCCCGTCGTGGCGGTTACTGTTTTGAGCAGAATGGCGTGTTTGAGCGTGTGTTA
CGCGAGCTGGGGTTTAACGTTCGCAGCTTGTTAGGGCGCGTAGTGTTATCAAATCCGCCAGCATTACCGCCGCGCACCCA
TCGTTTGCTGTTGGTGGAACTGGAAGGGGAAAAATGGATTGCTGATGTCGGTTTCGGTGGGCAGACGCTAACCGCGCCGA
TTCGTTTAATGCCGGATATCATGCAAACCACGCCACACGGAGAGTATCGGTTGTTGCAAGAGGGTGATGATTGGGTGTTG
CAGTTTAATCATCATCAGCACTGGCAGTCGATGTACCGTTTTGATCTCTGCGAGCAGCAACAAAGCGATTATGTGATGGG
CAATTTCTGGTCGGCGCATTGGCCGCAGTCGCATTTTCGCCATCATTTGCTGATGTGTCGCCATTTGCCGGACGGTGGCA
AGCTGACACTGACCAATTTTCATTTTACCCATTATGAAAATGGGCACGCAGTTAAGCAGCGAAATCTACCAGATGTGGCG
TCGTTATATGCCGTGATGCAGGAACAGTTTGGTCTGGGCGTAGATGATGCGAAACATGGCTTTACTGTGGATGAGTTAGC
GCTGGTGATGGCGGCGTTTGATACGCACCCGGAGGCGGGAAAATAA

Upstream 100 bases:

>100_bases
GCGATTTGCGAACGTGATGCATGTCCGCGATCGCACAAAATAGCCAGTGCGGCGTCTATTCCAGGTTATAAGTTGAGAAA
ACCACTAAGGGAAACGCCTG

Downstream 100 bases:

>100_bases
TTTATGTCAGGTTGCCGGATGTGGCGTAAATGCCTAATCCGGCATACATTAGTCCGGTTGTAGGCCTGATAAGCGAAGCG
CATCAGGCAACGGTTTCAGA

Product: N-hydroxyarylamine O-acetyltransferase

Products: NA

Alternate protein names: Arylamine N-acetyltransferase; Arylhydroxamate N,O-acetyltransferase; NAT102 [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVKQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Sequences:

>Translated_281_residues
MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVKQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
>Mature_280_residues
TPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVLR
ELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVLQ
FNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVKQRNLPDVAS
LYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649128, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI237649126, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI237649124, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI237649122, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI237649119, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI42741671, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI237649009, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI237649132, Length=290, Percent_Identity=23.7931034482759, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI237649130, Length=290, Percent_Identity=23.7931034482759, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787736, Length=281, Percent_Identity=96.44128113879, Blast_Score=549, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: =2.3.1.118 [H]

Molecular weight: Translated: 32291; Mature: 32160

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKL
CCCHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCEECCCEECCCHHHHHHHE
VIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWI
EEEECCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEE
ADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVKQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEECCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKL
CCHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCEECCCEECCCHHHHHHHE
VIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWI
EEEECCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEE
ADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVKQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEECCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]