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The map label for this gene is aroH

Identifier: 218699728

GI number: 218699728

Start: 1413679

End: 1414725

Strand: Reverse

Name: aroH

Synonym: ECIAI39_1349

Alternate gene names: 218699728

Gene position: 1414725-1413679 (Counterclockwise)

Preceding gene: 218699729

Following gene: 218699727

Centisome position: 27.57

GC content: 52.72

Gene sequence:

>1047_bases
ATGAACAGAACTGACGAACTCCGTACTGCGCGTATTGAGAGCCTGGTAACGCCCGCCGAACTCGCGCTACGGTATCCCGT
AACGACTGGCGTCGCCACCCATGTCACCGACTCCCGCCGTAGAATTGAAAAAATACTGAATGGTGAAGATAAGCGACTGT
TGGTCATTATTGGCCCCTGCTCGATCCACGATCTCACCGCTGCGATGGAGTACGCCACCCGTCTGCAGTCGCTGCGCAAC
CAGTACCAGTCACGGCTGGAAATCGTAATGCGCACCTATTTTGAAAAACCACGAACAGTTGTCGGCTGGAAAGGACTCAT
CTCCGATCCAGATTTAAACGGTAGCTATCGGGTAAATCACGGTCTGGAGCTGGCGCGCAAATTACTTTTACAGGTAAATG
AGCTGGGCGTCCCAACAGCGACTGAGTTCCTCGATATGGTGACCGGTCAGTTTATTGCTGATTTAATCAGTTGGGGCGCG
ATTGGCGCACGTACTACCGAAAGTCAGATCCACCGTGAAATGGCTTCGGCACTCTCCTGTCCGGTAGGTTTTAAAAATGG
TACCGATGGCAACACGCGGATTGCTGTGGATGCTATCCGCGCTGCCCGCGCCAGCCATATGTTCCTCTCACCAGACAAAA
ATGGTCAGATGACCATCTATCAGACCAGCGGCAACCCGTATGGCCACATTATTATGCGTGGCGGCAAAAAACCGAATTAT
CATGCCGATGATATCGCCGCAGCCTGCGATACGCTGCACGAGTTTGATTTACCTGAACATCTGGTGGTGGATTTCAGCCA
CGGTAACTGCCAGAAGCAGCACCGTCGCCAGTTAGAAGTTTGTGAGGATATTTGTCAGCAAATCCGCAATGGCTCTACGG
CGATTGCTGGAATTATGGCGGAAAGTTTCCTGCGCGAAGGAACGCAAAAAATCGTCGGCGGTCAGCCGCTCACTTACGGT
CAATCGATTACCGACCCGTGTCTGGGCTGGGAAGATACCGAACGCCTGGTCGAAAAACTCGCCTCTGCGGTTGATACCCG
CTTCTGA

Upstream 100 bases:

>100_bases
GACACACCTCGCACTTGAAATCAGCTGCGATTGGTTTATCGTGATGCGCATCACTTCCCGGTAGTCCTGCCGTAGAAGCA
ACAAATTTCTGAGACTTGTA

Downstream 100 bases:

>100_bases
ATGCGTGCCCATTCCTGACGGAATGGGCATTTCTGCGCAACTTGTTGTCTTCTCAACACATTACTGCTTGCTCTGGCCCG
CCAGAATATTGATAATAAGA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MNRTDELRTARIESLVTPAELALRYPVTTGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN
QYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY
HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG
QSITDPCLGWEDTERLVEKLASAVDTRF

Sequences:

>Translated_348_residues
MNRTDELRTARIESLVTPAELALRYPVTTGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN
QYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY
HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG
QSITDPCLGWEDTERLVEKLASAVDTRF
>Mature_348_residues
MNRTDELRTARIESLVTPAELALRYPVTTGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN
QYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY
HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG
QSITDPCLGWEDTERLVEKLASAVDTRF

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=99.4252873563218, Blast_Score=722, Evalue=0.0,
Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=57.1014492753623, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1788953, Length=329, Percent_Identity=49.5440729483283, Blast_Score=337, Evalue=7e-94,
Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=48.7106017191977, Blast_Score=334, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=42.7762039660057, Blast_Score=295, Evalue=8e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38710; Mature: 38710

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTDELRTARIESLVTPAELALRYPVTTGVATHVTDSRRRIEKILNGEDKRLLVIIGPC
CCCCHHHHHHHHHHHCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH
GLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY
CCCCCCCCCCCCEEHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMA
CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNRTDELRTARIESLVTPAELALRYPVTTGVATHVTDSRRRIEKILNGEDKRLLVIIGPC
CCCCHHHHHHHHHHHCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH
GLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY
CCCCCCCCCCCCEEHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMA
CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]