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The map label for this gene is znuA

Identifier: 218699571

GI number: 218699571

Start: 1261164

End: 1262096

Strand: Direct

Name: znuA

Synonym: ECIAI39_1192

Alternate gene names: 218699571

Gene position: 1261164-1262096 (Clockwise)

Preceding gene: 218699568

Following gene: 218699572

Centisome position: 24.57

GC content: 48.87

Gene sequence:

>933_bases
ATGTTACATAAAAAAACGCTTCTTTTCGCAGCATTATCCGCCGCTCTCTGGGGAGGTGCAACACAGGCCGCAGATGCCGC
CGTTGTCGCTTCGCTTAAACCCGTTGGGTTCATCGCTTCTGCCATTGCTGATGGGGTAACAGAAACGGAAGTTTTACTAC
CTGACGGCGCTTCAGAGCATGATTATTCACTGCGTCCATCAGATGTAAAACGCTTACAGAACGCGGACTTAGTCGTTTGG
GTTGGCCCGGAGATGGAAGCGTTCATGCAAAAACCGGTAAGTAAATTACCTGAAGCCAAACAGGTAACGATTGCGCAGCT
AGAGAATGTGAAACCGCTGCTGATGAAAAGTATTCACGGCGATGATGATGATCACGACCACGCGGAAAAAAGTGACGAAG
ATCACCATCACGGCGATTTCAACATGCATCTTTGGCTTTCCCCAGAGATAGCGCGGGCTACAGCGGTTGCAATCCATGGA
AAATTAGTGGAACTTATGCCGCAAAGTCGAGCCAAACTTGACGCCAACCTGAAGGATTTTGAGGCACAATTAGCCTCAAC
CGAAACGCAGGTTGGTCACGAGCTCGCGCCGCTCAAGGGGAAAGGTTATTTCGTTTTTCACGATGCTTACGGCTATTTCG
AAAAACAGTTCGGACTGACACCGCTTGGTCATTTTACCGTTAACCCTGAGATTCAACCTGGCGCGCAGCGTTTACATGAA
ATAAGAACACAGTTGGTTGAGCAAAAAGCAACCTGCGTTTTTGCTGAGCCACAGTTCAGGCCAACGGTCGTTGAGAGCGT
CGCACGAGGGACATCCGTTCGTATGGGAACGTTGGATCCCCTGGGGACGAATATCAAACTGGGTAAAACAAGCTATTCAG
AATTCCTGAATCAATTAGCCAACCAGTATGCGAGCTGCCTGAAAGGAGATTAA

Upstream 100 bases:

>100_bases
CCAGGGAAACCAGACTTGTCATGTTAATTTTAGTCTTGCAGTAGTCATGAAATGTTATAATATCACACTTCTCATATTGA
TTACGATGATTGGTCGCATT

Downstream 100 bases:

>100_bases
TGAGGAAGTGATTACGTGCAACAGATAGCCCGCTCTGTCGCCCTGGCGTTTAATAATTTACCGCGACCACACCGCGTTAT
GTTGGGGTCGCTCACCGTTC

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVW
VGPEMEAFMQKPVSKLPEAKQVTIAQLENVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
KLVELMPQSRAKLDANLKDFEAQLASTETQVGHELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHE
IRTQLVEQKATCVFAEPQFRPTVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLNQLANQYASCLKGD

Sequences:

>Translated_310_residues
MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVW
VGPEMEAFMQKPVSKLPEAKQVTIAQLENVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
KLVELMPQSRAKLDANLKDFEAQLASTETQVGHELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHE
IRTQLVEQKATCVFAEPQFRPTVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLNQLANQYASCLKGD
>Mature_310_residues
MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVW
VGPEMEAFMQKPVSKLPEAKQVTIAQLENVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
KLVELMPQSRAKLDANLKDFEAQLASTETQVGHELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHE
IRTQLVEQKATCVFAEPQFRPTVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLNQLANQYASCLKGD

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=310, Percent_Identity=98.3870967741936, Blast_Score=629, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33929; Mature: 33929

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCCC
DYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQVTIAQLENVKPLLMKSIHG
CCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCC
DDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHGKLVELMPQSRAKLDANLKDF
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHH
EAQLASTETQVGHELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHE
HHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEECCCCCHHHHHHHH
IRTQLVEQKATCVFAEPQFRPTVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLNQLA
HHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCEEECCCHHHHHHHHHH
NQYASCLKGD
HHHHHHHCCC
>Mature Secondary Structure
MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCCC
DYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQVTIAQLENVKPLLMKSIHG
CCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCC
DDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHGKLVELMPQSRAKLDANLKDF
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHH
EAQLASTETQVGHELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHE
HHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEECCCCCHHHHHHHH
IRTQLVEQKATCVFAEPQFRPTVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLNQLA
HHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCEEECCCHHHHHHHHHH
NQYASCLKGD
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 9600841; 9680209 [H]