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The map label for this gene is torY

Identifier: 218699555

GI number: 218699555

Start: 1245869

End: 1246969

Strand: Direct

Name: torY

Synonym: ECIAI39_1176

Alternate gene names: 218699555

Gene position: 1245869-1246969 (Clockwise)

Preceding gene: 218699554

Following gene: 218699556

Centisome position: 24.28

GC content: 47.05

Gene sequence:

>1101_bases
ATGCGAGGGAAAAAACGCATTGGGTTATTATTTTTGCTGATAACGGTTGTGGTTGGTGGCGGCGGGTTATTACTGGCGCA
AAAAGCCTTACATAAAACGTCGGATACAGCATTTTGCCTTTCCTGCCACTCGATGAGTAAACCTTTTGAGGAATATCAGG
GAACTGTCCACTTTTCTAACCAGAAAGGGATACGTGCGGAATGTGCCGATTGCCATATTCCAAAGTCAGGGATGGATTAT
TTATTTGCTAAATTAAAAGCATCTAAAGATATTTATCATGAATTTGTTAGCGGCAAAATAGACAGTGACGATAAGTTCGA
AGCGCATCGTCAGGAAATGGCCGAAACAGTATGGAAAGAATTAAAAGCATCGGATTCTGCAACGTGCCGTAGTTGCCATT
CTTTTGATGCGATGGATATTGCCTCGCAAAGTGAATCTGCGCAGAAAATGCATACCAAAGCGCAAAAGGACGGTGAAACG
TGTATTGATTGTCATAAAGGCATTGCCCATTTCCCGCCAGAAATAAAAATGGATGACAACGCGGCGCATGAACTGGAAAG
TCAGGCTGCCACTTCTGTGACCAATGGCGCACATATTTATCCTTTCAAACCTTCCCGCATAGGCGAACTGGCCACTGTGA
ATCCTGGTACCGATCTCACCGTCGTTGATGCCAGTGGCAAACAGCCGATCGTTCTGTTGCAGGGTTATCAAATGCAGGGC
AGTGAAAGCACGCTCTATCTGGCGGCAGGTCAACGTCTGGCGCTAGCCACATTAAGTGATGAAGGTATCAAGGCGCTAAC
GGTAAACGGGGAATGGCAGGCTGACGAATACGGTAATCAATGGCGTCAGGCGTCATTACAAGGGGCGCTAATCGATCCCG
TATTAGCGGATCGTAAACCGTTATGGCAATACGCTGAAAAACTCGATGACACCTATTGTGCTGGCTGCCATGCCCCTATT
GCCGCCGACCATTACACCGTCAATACATGGCCGTCCATTGCCAAAGGAATGGGTGCGCGAACCAGCATGAGCGAAAACGA
ACTGGACATTTTGACGCGGTACTTCCAGTACAACGCCAAAGATATTACCGAGAAACAGTGA

Upstream 100 bases:

>100_bases
TTATTTCAGGCAGTGTTGTGCCGAATTATGCAAGCGGTCAATTCGTTGTATATTTAATTATACAATGATTTCGGTGTTCT
GGAATTAATTAGAGGAATCT

Downstream 100 bases:

>100_bases
TCCTCGTTGATCAGGGAGGAAGTTATGACATTAACAAGACGTGAATTTATTAAACACAGCGGTATTGCCGCTGGGGCGCT
GGTGGTGACATCGGCTGCAC

Product: TMAO reductase III (TorYZ), cytochrome c-type subunit

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRGKKRIGLLFLLITVVVGGGGLLLAQKALHKTSDTAFCLSCHSMSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDY
LFAKLKASKDIYHEFVSGKIDSDDKFEAHRQEMAETVWKELKASDSATCRSCHSFDAMDIASQSESAQKMHTKAQKDGET
CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKPSRIGELATVNPGTDLTVVDASGKQPIVLLQGYQMQG
SESTLYLAAGQRLALATLSDEGIKALTVNGEWQADEYGNQWRQASLQGALIDPVLADRKPLWQYAEKLDDTYCAGCHAPI
AADHYTVNTWPSIAKGMGARTSMSENELDILTRYFQYNAKDITEKQ

Sequences:

>Translated_366_residues
MRGKKRIGLLFLLITVVVGGGGLLLAQKALHKTSDTAFCLSCHSMSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDY
LFAKLKASKDIYHEFVSGKIDSDDKFEAHRQEMAETVWKELKASDSATCRSCHSFDAMDIASQSESAQKMHTKAQKDGET
CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKPSRIGELATVNPGTDLTVVDASGKQPIVLLQGYQMQG
SESTLYLAAGQRLALATLSDEGIKALTVNGEWQADEYGNQWRQASLQGALIDPVLADRKPLWQYAEKLDDTYCAGCHAPI
AADHYTVNTWPSIAKGMGARTSMSENELDILTRYFQYNAKDITEKQ
>Mature_366_residues
MRGKKRIGLLFLLITVVVGGGGLLLAQKALHKTSDTAFCLSCHSMSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDY
LFAKLKASKDIYHEFVSGKIDSDDKFEAHRQEMAETVWKELKASDSATCRSCHSFDAMDIASQSESAQKMHTKAQKDGET
CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKPSRIGELATVNPGTDLTVVDASGKQPIVLLQGYQMQG
SESTLYLAAGQRLALATLSDEGIKALTVNGEWQADEYGNQWRQASLQGALIDPVLADRKPLWQYAEKLDDTYCAGCHAPI
AADHYTVNTWPSIAKGMGARTSMSENELDILTRYFQYNAKDITEKQ

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme [H]

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1788181, Length=366, Percent_Identity=96.7213114754098, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1787230, Length=374, Percent_Identity=34.2245989304813, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1788530, Length=180, Percent_Identity=43.8888888888889, Blast_Score=161, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 40276; Mature: 40276

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGKKRIGLLFLLITVVVGGGGLLLAQKALHKTSDTAFCLSCHSMSKPFEEYQGTVHFSN
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHCCEEEECC
QKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDSDDKFEAHRQEMAETVWKE
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LKASDSATCRSCHSFDAMDIASQSESAQKMHTKAQKDGETCIDCHKGIAHFPPEIKMDDN
HHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCEECCC
AAHELESQAATSVTNGAHIYPFKPSRIGELATVNPGTDLTVVDASGKQPIVLLQGYQMQG
HHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCCEEEEECCCCCCEEEEECCEECC
SESTLYLAAGQRLALATLSDEGIKALTVNGEWQADEYGNQWRQASLQGALIDPVLADRKP
CCCEEEEECCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHCHHHHCCCH
LWQYAEKLDDTYCAGCHAPIAADHYTVNTWPSIAKGMGARTSMSENELDILTRYFQYNAK
HHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
DITEKQ
CCCCCC
>Mature Secondary Structure
MRGKKRIGLLFLLITVVVGGGGLLLAQKALHKTSDTAFCLSCHSMSKPFEEYQGTVHFSN
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHCCEEEECC
QKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDSDDKFEAHRQEMAETVWKE
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LKASDSATCRSCHSFDAMDIASQSESAQKMHTKAQKDGETCIDCHKGIAHFPPEIKMDDN
HHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCEECCC
AAHELESQAATSVTNGAHIYPFKPSRIGELATVNPGTDLTVVDASGKQPIVLLQGYQMQG
HHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCCEEEEECCCCCCEEEEECCEECC
SESTLYLAAGQRLALATLSDEGIKALTVNGEWQADEYGNQWRQASLQGALIDPVLADRKP
CCCEEEEECCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHCHHHHCCCH
LWQYAEKLDDTYCAGCHAPIAADHYTVNTWPSIAKGMGARTSMSENELDILTRYFQYNAK
HHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
DITEKQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]