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The map label for this gene is modF

Identifier: 218699125

GI number: 218699125

Start: 771164

End: 772636

Strand: Reverse

Name: modF

Synonym: ECIAI39_0728

Alternate gene names: 218699125

Gene position: 772636-771164 (Counterclockwise)

Preceding gene: 218699126

Following gene: 218699124

Centisome position: 15.06

GC content: 52.41

Gene sequence:

>1473_bases
ATGTCATCGTTGCAAATTTTGCAAGGCACGTTTCGTCTTGGCGACACAAAAACGCTGCAATTGCCTCAGCTAACGTTAAA
CGCGGGTGATAGTTGGGCGTTTGTCGGTTCGAATGGAAGCGGGAAATCGGCGCTGGCCCGCGCGCTGGCAGGTGAACTTC
CGCTTTTGAAAGGTGAACGGCAAAGCCAGTTTTCCCACATCACTCGTCTCTCCTTCGAGCAATTGCAAAAGCTCGTCAGC
GACGAATGGCAGCGGAATAACACCGATATGCTCGGCCCTGGCGAAGATGACACCGGACGCACTACGGCTGAGATTATTCA
GGATGAAGTAAAGGATGCACCGCGCTGCATGCAACTGGCACAGCAGTTCGGTATTACCGCCCTCCTCGACCGACGCTTTA
AATACCTTTCCACTGGCGAGACGCGAAAAACCCTGCTGTGTCAGGCGCTGATGTCGGAGCCTGACTTGTTGATTCTTGAT
GAGCCGTTCGATGGCCTGGATGTTGCCTCACGTCAGCAGCTGGCTGAGCTACTCGCCTCGTTACATCAGTCCGGTATTAC
TCTGGTACTGGTGCTCAATCGCTTCGATGAGATCCCAGAATTTGTCCAGTTTGCTGGCGTGCTGGCGGATTGCACGTTAG
CGGAAACTGGCGCTAAAGAAGAACTGCTCCAACAAGCACTCGTTGCGCAACTGGCGCATAGCGAACTGCTTGAAGGTGTG
CAAATGCCGGAGCCGGATGAACCTTCAGCACGTCACGCCTTACCCGCCAACGAACCGCGCATTGTGCTGAACAATGGCGT
GGTTTCTTATAACGAACGCCCCATTCTTAATAACCTTAGCTGGCAGGTGAATCCAGGCGAACACTGGCAAATTGTCGGGC
CAAATGGCGCGGGAAAATCGACGTTATTAAGCCTGATTACTGGCGATCATCCGCAAGGTTACAGCAACGATTTGACGCTT
TTCGGACGACGTCGCGGCAGCGGCGAAACCATCTGGGATATCAAAAAGCATATCGGTTACGTCAGCAGTAGTTTGCATCT
GGATTACCGGGTCAGCACTACTGTGCGTAATGTGATTCTTTCTGGCTATTTTGATTCGATTGGCATTTATCAGGCCGTTT
CGGATCGCCAGCAAAAACTGGTGCAGCAGTGGCTGGATATTCTCGGCATTGATAAACGCACGGCTGACGCTCCGTTCCAT
AGTCTTTCCTGGGGACAGCAGCGTCTGGCGCTGATCGTCCGCGCGCTGGTGAAACATCCGACGTTGCTTATTCTCGATGA
ACCACTACAGGGGCTTGATCCGCTCAATCGCCAGCTTATCCGCCGGTTTGTTGATGTGCTGATTAGCGAAGGTGAAACGC
AATTGTTGTTTGTTTCGCACCATGCTGAAGATGCGCCTGCCTGTATTACCCATCGTCTTGAGTTCGTGCCGGACGGTGAA
CTCTATCGCTATGTGCTGACAAAAATAAACTGA

Upstream 100 bases:

>100_bases
GCCGACAGCGTGATTATCGCCACGCTGTGCTAAGCATGTTGACAATTTGTTATGAAACACGTATCCCTGTCAGTAATCGC
TGCACAAAATGGGATATAAA

Downstream 100 bases:

>100_bases
GTCGGTAATGCTGACCGTGCCGGAGGCGGCCTAAGCGCCCTCTCCGGCCTACAGTTCGACGCATGCAGGCATGAAACCGC
GTCTTTTTTTCAGATAAAAA

Product: putative molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSELLEGV
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGE
LYRYVLTKIN

Sequences:

>Translated_490_residues
MSSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSELLEGV
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGE
LYRYVLTKIN
>Mature_489_residues
SSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSD
EWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDE
PFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSELLEGVQ
MPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHS
LSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGEL
YRYVLTKIN

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=167, Percent_Identity=28.1437125748503, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI27262626, Length=167, Percent_Identity=28.1437125748503, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1786975, Length=489, Percent_Identity=98.5685071574642, Blast_Score=983, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=379, Percent_Identity=27.9683377308707, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788897, Length=502, Percent_Identity=23.3067729083665, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789991, Length=467, Percent_Identity=24.4111349036403, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48995001, Length=464, Percent_Identity=23.9224137931034, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=22.4074074074074, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788506, Length=506, Percent_Identity=25.098814229249, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790525, Length=491, Percent_Identity=21.1812627291242, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790190, Length=480, Percent_Identity=23.3333333333333, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787792, Length=480, Percent_Identity=23.3333333333333, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI2367384, Length=531, Percent_Identity=23.728813559322, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI145693107, Length=517, Percent_Identity=23.4042553191489, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787029, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789593, Length=223, Percent_Identity=28.2511210762332, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786319, Length=209, Percent_Identity=30.1435406698565, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788225, Length=180, Percent_Identity=28.3333333333333, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788472, Length=478, Percent_Identity=21.7573221757322, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081782, Length=209, Percent_Identity=28.2296650717703, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=217, Percent_Identity=25.3456221198157, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787500, Length=242, Percent_Identity=26.0330578512397, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786563, Length=197, Percent_Identity=30.4568527918782, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082268, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787112, Length=230, Percent_Identity=27.8260869565217, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788761, Length=219, Percent_Identity=26.9406392694064, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786703, Length=204, Percent_Identity=30.3921568627451, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786803, Length=232, Percent_Identity=23.7068965517241, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=229, Percent_Identity=28.3842794759825, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=236, Percent_Identity=28.8135593220339, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320266, Length=394, Percent_Identity=29.6954314720812, Blast_Score=163, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24650855, Length=237, Percent_Identity=32.0675105485232, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650853, Length=237, Percent_Identity=32.0675105485232, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362751, Length=226, Percent_Identity=32.3008849557522, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221512771, Length=202, Percent_Identity=26.2376237623762, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28574744, Length=196, Percent_Identity=28.0612244897959, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920532, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580930, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85725262, Length=214, Percent_Identity=29.9065420560748, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54518; Mature: 54387

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGER
CCCHHHHHHHHCCCCCCEEECCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSELLEGV
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCH
LYRYVLTKIN
HHHHHHHHCC
>Mature Secondary Structure 
SSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGER
CCHHHHHHHHCCCCCCEEECCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSELLEGV
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCH
LYRYVLTKIN
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]