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The map label for this gene is iraD

Identifier: 218698170

GI number: 218698170

Start: 5075689

End: 5076081

Strand: Direct

Name: iraD

Synonym: EC55989_4992

Alternate gene names: 218698170

Gene position: 5075689-5076081 (Clockwise)

Preceding gene: 218698169

Following gene: 218698175

Centisome position: 98.46

GC content: 48.85

Gene sequence:

>393_bases
ATGATGCGCCAATCACTTCAGGCTGTTTTACCTGAAATTTCAGGCAATAAAACGTCACCGCTGCGTAAATCAGTATGCAG
CGATCTCCTCACTCTTTTTAATTCTCCTCATTCGGCATTACCGTCATTACTTGTTTCAGGCATGCCCGAGTGGCAAGTGC
ATAACCCGAGCGACAAACATCTCCAGAGCTGGTATTGCCGTCAGCTGCGTTCTGCACTGTTATTTCATGAGCCACGGATT
GCAGCGTTGCAGGTTAATCTGAAAGAAGCGTACTGCCACACTCTGGCGATCAGCCTTGAGATAATGCTGTACCACGACGA
TGAATCGCTAACGTTTGATCTGGTCTGGGATAATGGCGGTTGGCGCAGTGCGACGCTGGAGAATGTCAGCTAA

Upstream 100 bases:

>100_bases
ATGAACAAAAGGGAATGGCTATGGAAAATGAGCATCAATACAGTGGTGCCCGGTGTTCAGGGCAAGCCGCATATGTTGCT
AAACGTCAGGAGTGCGCAAA

Downstream 100 bases:

>100_bases
GCACAATCTCCAGCTCGCGCAGTTCACGCCAGAAGCGTTCGGCAACTGGATTCATGCGGGTATTCATCCGGTATGCATAG
GCCTGAATCGGGATCACCAG

Product: DNA replication/recombination/repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRI
AALQVNLKEAYCHTLAISLEIMLYHDDESLTFDLVWDNGGWRSATLENVS

Sequences:

>Translated_130_residues
MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRI
AALQVNLKEAYCHTLAISLEIMLYHDDESLTFDLVWDNGGWRSATLENVS
>Mature_130_residues
MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRI
AALQVNLKEAYCHTLAISLEIMLYHDDESLTFDLVWDNGGWRSATLENVS

Specific function: Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of Rss

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GpW/Gp25 family. IraD subfamily

Homologues:

Organism=Escherichia coli, GI87082422, Length=130, Percent_Identity=98.4615384615385, Blast_Score=264, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IRAD_ECO24 (A7ZVM4)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001465853.1
- STRING:   A7ZVM4
- EnsemblBacteria:   EBESCT00000021194
- GeneID:   5590870
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_4926
- eggNOG:   NOG15434
- GeneTree:   EBGT00050000011257
- HOGENOM:   HBG467531
- ProtClustDB:   PRK14128
- BioCyc:   ECOL331111:ECE24377A_4926-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02010
- InterPro:   IPR007048

Pfam domain/function: PF04965 GPW_gp25

EC number: NA

Molecular weight: Translated: 14747; Mature: 14747

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKH
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCCHHH
LQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDESLTFDLVWDNGG
HHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHEEEEEEEEEECCCCEEEEEEECCCC
WRSATLENVS
CCCCCCCCCC
>Mature Secondary Structure
MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKH
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCCHHH
LQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDESLTFDLVWDNGG
HHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHEEEEEEEEEECCCCEEEEEEECCCC
WRSATLENVS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA