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The map label for this gene is atpA

Identifier: 218697460

GI number: 218697460

Start: 4298609

End: 4300150

Strand: Reverse

Name: atpA

Synonym: EC55989_4209

Alternate gene names: 218697460

Gene position: 4300150-4298609 (Counterclockwise)

Preceding gene: 218697461

Following gene: 218697459

Centisome position: 83.42

GC content: 53.37

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACCGAAATCAGCGAACTGATCAAGCAGCGCATTGCTCAGTTCAATGTTGTGAGTGAAGCTCACAA
CGAAGGTACTATTGTTTCTGTAAGTGACGGTGTTATCCGCATTCACGGCCTGGCCGATTGTATGCAGGGTGAAATGATCT
CCCTGCCGGGTAACCGTTACGCTATCGCACTGAACCTCGAGCGCGACTCTGTAGGTGCGGTTGTTATGGGTCCGTACGCT
GACCTTGCCGAAGGCATGAAAGTTAAGTGTACTGGCCGTATCCTGGAAGTTCCGGTTGGCCGTGGCCTGCTGGGCCGTGT
GGTTAACACTCTGGGTGCACCAATCGACGGTAAAGGTCCGCTGGATCACGACGGCTTCTCTGCTGTAGAAGCAATCGCTC
CGGGCGTTATCGAACGTCAGTCCGTAGATCAGCCGGTACAGACCGGTTATAAAGCCGTTGACTCCATGATCCCAATCGGT
CGTGGTCAGCGTGAATTGATCATCGGTGACCGTCAGACAGGTAAAACCGCACTGGCTATCGATGCCATCATCAACCAGCG
CGATTCCGGTATCAAATGTATCTATGTCGCTATCGGCCAGAAAGCGTCCACCATTTCTAACGTGGTACGTAAACTGGAAG
AGCACGGCGCACTGGCTAACACCATCGTTGTGGTAGCAACCGCGTCTGAATCCGCTGCACTGCAATACCTGGCACCGTAT
GCCGGTTGCGCAATGGGCGAATACTTCCGTGACCGCGGTGAAGATGCGCTGATCATTTACGATGACCTGTCTAAACAGGC
TGTTGCTTACCGTCAGATCTCCCTGCTGCTCCGTCGTCCGCCAGGACGTGAAGCATTCCCGGGCGACGTTTTCTACCTCC
ACTCTCGTCTGCTGGAGCGTGCTGCACGTGTTAACGCCGAATACGTTGAAGCCTTCACCAAAGGTGAAGTGAAAGGGAAA
ACCGGTTCTCTGACCGCACTGCCGATTATCGAAACTCAGGCGGGTGACGTTTCTGCGTTCGTTCCGACCAACGTAATCTC
CATTACCGATGGTCAGATCTTCCTGGAAACCAACCTGTTCAACGCCGGTATTCGTCCTGCGGTTAACCCGGGTATTTCCG
TATCCCGTGTTGGTGGTGCAGCACAGACCAAGATCATGAAAAAACTGTCCGGTGGTATCCGTACCGCTCTGGCACAGTAT
CGTGAACTGGCAGCGTTCTCTCAGTTTGCATCCGACCTTGACGATGCAACACGTAAGCAGCTTGACCACGGTCAGAAAGT
GACCGAACTGCTGAAACAGAAACAGTATGCGCCGATGTCCGTTGCGCAGCAGTCTCTGGTTCTGTTCGCAGCAGAACGTG
GTTACCTGGCGGATGTTGAACTGTCGAAAATTGGCAGCTTCGAAGCCGCTCTGCTGGCTTACGTCGACCGTGATCACGCT
CCGTTGATGCAAGAGATCAACCAGACCGGTGGCTACAACGACGAAATCGAAGGCAAGCTGAAAGGCATCCTCGATTCCTT
CAAAGCAACCCAATCCTGGTAA

Upstream 100 bases:

>100_bases
AGGCGTTATCATCCGAGCGGGTGATATGGTCATTGATGGCAGCGTACGCGGTCGTCTTGAGCGCCTTGCAGACGTCTTGC
AGTCTTAAGGGGACTGGAGC

Downstream 100 bases:

>100_bases
CGTCTGGCGGCTTGCCTTAGGGCAGGCCGCAAGGCATTGAGGAGAAGCTCATGGCCGGCGCAAAAGAGATACGTAGTAAG
ATCGCAAGCGTCCAGAACAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHA
PLMQEINQTGGYNDEIEGKLKGILDSFKATQSW

Sequences:

>Translated_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHA
PLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
>Mature_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHA
PLMQEINQTGGYNDEIEGKLKGILDSFKATQSW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=56.5302144249513, Blast_Score=559, Evalue=1e-159,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=56.5302144249513, Blast_Score=559, Evalue=1e-159,
Organism=Homo sapiens, GI19913428, Length=314, Percent_Identity=28.9808917197452, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913426, Length=329, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI32189394, Length=435, Percent_Identity=24.367816091954, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI19913424, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=100, Blast_Score=1044, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=26.1764705882353, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=24.9275362318841, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=55.1456310679612, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=55.1456310679612, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.4563106796116, Blast_Score=506, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.8152173913043, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=313, Percent_Identity=27.4760383386581, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=448, Percent_Identity=24.5535714285714, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=68.0851063829787, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=27.1653543307087, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=53.2163742690059, Blast_Score=553, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6319603, Length=370, Percent_Identity=25.6756756756757, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=446, Percent_Identity=25.3363228699552, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.863813229572, Blast_Score=548, Evalue=1e-156,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.7955271565495, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.7955271565495, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.7955271565495, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24638766, Length=434, Percent_Identity=25.3456221198157, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=25.2336448598131, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24583992, Length=259, Percent_Identity=28.1853281853282, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583988, Length=259, Percent_Identity=28.1853281853282, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583986, Length=259, Percent_Identity=28.1853281853282, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583984, Length=259, Percent_Identity=28.1853281853282, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55223; Mature: 55223

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
LDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEECHHHHCCCHHHHHHHHHCCCCC
PLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
LDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEECHHHHCCCHHHHHHHHHCCCCC
PLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA