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The map label for this gene is yieK

Identifier: 218697441

GI number: 218697441

Start: 4273841

End: 4274563

Strand: Reverse

Name: yieK

Synonym: EC55989_4188

Alternate gene names: 218697441

Gene position: 4274563-4273841 (Counterclockwise)

Preceding gene: 218697442

Following gene: 218697437

Centisome position: 82.92

GC content: 49.52

Gene sequence:

>723_bases
ATGAAATTAATCATTACCGAAGATTACCAGGAAATGAGCCGTGTCGCGGCACACCATCTGCTTGGTTATATGTCGAAGAC
GCGTCGTGTTAACCTGGCAATTACCGCCGGTAGCACGCCCAAAGGCATGTATGAATACCTCACCACCCTGGTTAAAGGTA
AGCCCTGGTATGATAACTGCTATTTCTATAATTCCGATGAAATTCCCTTTCGCGGCAAAGAGGGAGAAGGTGTAACGATT
ACCAATCTGCGTAATCTGTTTTTCACCCCTGCGGGGATCAAAGAAGAGAATATCCAGAAGCTCACTATTGATAACTACCG
CGAGCATGATCAGAAACTGGCGCGTGAAGGCGGCCTGGATTTGGTGGTGCTGGGATTAGGTGCAGATGGTCATTTTTGTG
GCAATTTGCCGAATACGACCCATTTCCATGAGCAAACCGTGGAGTTCCCGATCCAGGGAGAGATGGTTGATATTGTGGCG
CATGGTGAGTTGGGCGGCGACTTTTCGTTAGTGCCTGACAGCTACGTGACGATGGGGCCGAAAAGCATCATGGCGGCGAA
AAACTTGCTGATAATTGTCAGTGGCGCAGGTAAAGCGCAGGCACTGAAAAATGTGCTGCAAGGTCCGGTTACCGAAGATG
TTCCAGCTTCCGTGTTGCAGCTGCATCCTTCGCTGATGGTAATCGCTGATAAAGCCGCTGCCGCAGAATTAGCGCTCGAT
TAA

Upstream 100 bases:

>100_bases
ATTACCAGGAATATCCCGGCCTGAACCATGAAATGGATGTCTGGCGGCCTGCCTATGCAGCCTTCGTACAGAAATTATTT
AAATAAAATAAGGCACTAAG

Downstream 100 bases:

>100_bases
GCTGAAGAAATAAGGCCGGATGTATGAATTACGCTCCGGCCTGTTCTCATTATTTAAATAACTACGAAAAATCACCCCAC
AGTCTCAGCTTGCCGCAGTG

Product: putative 6-phosphogluconolactonase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMYEYLTTLVKGKPWYDNCYFYNSDEIPFRGKEGEGVTI
TNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVIADKAAAAELALD

Sequences:

>Translated_240_residues
MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMYEYLTTLVKGKPWYDNCYFYNSDEIPFRGKEGEGVTI
TNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVIADKAAAAELALD
>Mature_240_residues
MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMYEYLTTLVKGKPWYDNCYFYNSDEIPFRGKEGEGVTI
TNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVIADKAAAAELALD

Specific function: Unknown

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=252, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI19923881, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI48994958, Length=239, Percent_Identity=99.581589958159, Blast_Score=493, Evalue=1e-141,
Organism=Escherichia coli, GI1789530, Length=247, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786893, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17554876, Length=250, Percent_Identity=27.6, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24581960, Length=249, Percent_Identity=26.1044176706827, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920764, Length=249, Percent_Identity=26.1044176706827, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: NA

Molecular weight: Translated: 26277; Mature: 26277

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMYEYLTTLVKGKPWYDNC
CEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCE
YFYNSDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLD
EEECCCCCCCCCCCCCCEEEEEEHHHEECCCCCCCCCCEEEECCCHHHHHHHHHHHCCCE
LVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVAHGELGGDFSLVPDSYVTMGP
EEEEEECCCCCEECCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCEEECCCCCEECCC
KSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVIADKAAAAELALD
HHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECCCCCHHCCCC
>Mature Secondary Structure
MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMYEYLTTLVKGKPWYDNC
CEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCE
YFYNSDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLD
EEECCCCCCCCCCCCCCEEEEEEHHHEECCCCCCCCCCEEEECCCHHHHHHHHHHHCCCE
LVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVAHGELGGDFSLVPDSYVTMGP
EEEEEECCCCCEECCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCEEECCCCCEECCC
KSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVIADKAAAAELALD
HHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]