Click here to switch to the map view.

The map label for this gene is ibpA

Identifier: 218697409

GI number: 218697409

Start: 4242170

End: 4242583

Strand: Reverse

Name: ibpA

Synonym: EC55989_4156

Alternate gene names: 218697409

Gene position: 4242583-4242170 (Counterclockwise)

Preceding gene: 218697411

Following gene: 218697408

Centisome position: 82.3

GC content: 47.34

Gene sequence:

>414_bases
ATGCGTAACTTTGATTTATCCCCGCTTTACCGTTCTGCTATTGGATTTGACCGTTTGTTTAACCACTTAGAAAACAACCA
GAGCCAGAGTAATGGCGGCTACCCTCCGTATAACGTTGAACTGGTAGACGAAAACCATTACCGCATTGCTATCGCTGTGG
CTGGTTTTGCTGAGAGCGAACTGGAAATTACCGCCCAGGATAATCTGCTGGTGGTGAAAGGTGCTCACGCCGACGAACAA
AAAGAGCGCACCTATCTGTACCAGGGCATCGCTGAACGCAACTTTGAACGCAAATTCCAGTTAGCTGAGAACATTCATGT
TCGTGGCGCTAACCTGGTAAATGGTTTGCTGTATATCGATCTCGAACGCGTGATTCCGGAAGCGAAAAAACCGCGCCGTA
TCGAAATCAACTAA

Upstream 100 bases:

>100_bases
CATCGTAGCCGATGAGGACGCGCCTGATGGGTGTTCTGGCTACCTGACCTGTCCATTGTGGAAGGTCTTACATTCTCGCT
GATTTCAGGAGCTATTGATT

Downstream 100 bases:

>100_bases
TTCCCTAAGGCCGCCTGGCGCGGCCTGACATCTCCATGCTCGCCGTCAGGGAGCATATGCGAATCTTCGGATTTGCAGGT
ACTTACTCGCTTCTTAGAAG

Product: heat shock protein IbpA

Products: NA

Alternate protein names: 16 kDa heat shock protein A [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQ
KERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN

Sequences:

>Translated_137_residues
MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQ
KERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
>Mature_137_residues
MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQ
KERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN

Specific function: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently ref

COG id: COG0071

COG function: function code O; Molecular chaperone (small heat shock protein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small heat shock protein (HSP20) family [H]

Homologues:

Organism=Escherichia coli, GI1790122, Length=137, Percent_Identity=100, Blast_Score=278, Evalue=8e-77,
Organism=Escherichia coli, GI87082316, Length=138, Percent_Identity=50.7246376811594, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002068
- InterPro:   IPR008978 [H]

Pfam domain/function: PF00011 HSP20 [H]

EC number: NA

Molecular weight: Translated: 15774; Mature: 15774

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS01031 HSP20

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESE
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCC
LEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYID
EEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCHHHCEEEEEE
LERVIPEAKKPRRIEIN
HHHHCCCCCCCEEEECC
>Mature Secondary Structure
MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESE
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCC
LEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYID
EEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCHHHCEEEEEE
LERVIPEAKKPRRIEIN
HHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA