| Definition | Escherichia coli 55989, complete genome. |
|---|---|
| Accession | NC_011748 |
| Length | 5,154,862 |
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The map label for this gene is dppD
Identifier: 218697253
GI number: 218697253
Start: 4069474
End: 4070457
Strand: Reverse
Name: dppD
Synonym: EC55989_3992
Alternate gene names: 218697253
Gene position: 4070457-4069474 (Counterclockwise)
Preceding gene: 218697254
Following gene: 218697252
Centisome position: 78.96
GC content: 56.5
Gene sequence:
>984_bases ATGGCGTTATTAAATGTAGATAAATTATCGGTGCATTTCGGCGACGAAAGCGCGCCGTTCCGCGCCGTAGACCGCATCAG CTACAGCGTAAAACAGGGCGAAGTGGTCGGGATTGTGGGTGAGTCCGGCTCCGGTAAGTCGGTCAGTTCACTGGCGATTA TGGGGCTGATTGATTATCCGGGCCGCGTAATGGCAGAAAAACTGGAGTTTAACGGCCAGGATTTGCAGCGTATCTCAGAA AAAGAGCGCCGCAACCTGGTGGGTGCCGAAGTGGCGATGATCTTCCAGGACCCGATGACCAGCCTTAACCCGTGCTACAC CGTGGGTTTCCAGATTATGGAAGCGATTAAGGTGCATCAGGGCGGCAACAAAAGTACCCGCCGTCAGCGAGCGATTGACC TGCTGAATCAGGTCGGTATTCCCGATCCGGCATCGCGTCTGGATGTTTACCCGCATCAGCTTTCCGGCGGCATGAGCCAG CGCGTGATGATCGCCATGGCGATTGCCTGTCGGCCAAAACTGCTGATTGCCGATGAACCGACCACCGCGCTGGACGTGAC CATTCAGGCGCAAATCATCGAACTACTGCTGGAGCTACAGCAGAAAGAGAACATGGCGCTGGTGTTAATTACCCATGACC TGGCGCTGGTGGCGGAAGCGGCACATAAAATCATCGTGATGTATGCAGGCCAGGTGGTGGAAACCGGTGATGCGCACGCC ATCTTCCATGCGCCGCGTCACCCGTATACTCAGGCATTGCTGCGTGCGCTGCCAGAATTTGCTCAGGACAAAGAACGTCT GGCGTCGTTGCCAGGTGTCGTTCCCGGTAAGTACGACCGCCCGAACGGCTGCCTGCTTAACCCGCGCTGCCCCTATGCCA CTGACAGATGTCGCGCTGAAGAACCGGCGCTGAATATGCTCGCTGATGGGCGTCAGTCCAAATGCCATTACCCACTTGAT GATGCCGGGAGGCCGACACTATGA
Upstream 100 bases:
>100_bases CCGGGTCTGGCGATCCTGCTGACGGTGCTGGCATTTAACCTGATGGGTGACGGTCTGCGTGACGCGCTCGATCCCAAACT GAAGCAGTAAGAGGTTCGAG
Downstream 100 bases:
>100_bases GTACGCAAGAGGCCACCTCGCAACAACCGCTGTTGCAGGCTATCGACCTGAAAAAACATTATCCGGTGAAGAAAGGCATG TTCGCGCCGGAACGTCTGGT
Product: dipeptide transporter ATP-binding subunit
Products: ADP; phosphate; dipeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 327; Mature: 326
Protein sequence:
>327_residues MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISE KERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHA IFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLD DAGRPTL
Sequences:
>Translated_327_residues MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISE KERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHA IFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLD DAGRPTL >Mature_326_residues ALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEK ERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQR VMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHAI FHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLDD AGRPTL
Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential)
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain
Homologues:
Organism=Homo sapiens, GI9961252, Length=243, Percent_Identity=30.4526748971193, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4505771, Length=243, Percent_Identity=30.4526748971193, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI9961250, Length=243, Percent_Identity=30.4526748971193, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI42490749, Length=242, Percent_Identity=28.099173553719, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI9665248, Length=221, Percent_Identity=29.8642533936652, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI1789963, Length=327, Percent_Identity=100, Blast_Score=672, Evalue=0.0, Organism=Escherichia coli, GI48994883, Length=320, Percent_Identity=45.625, Blast_Score=296, Evalue=1e-81, Organism=Escherichia coli, GI1787548, Length=328, Percent_Identity=43.9024390243902, Blast_Score=270, Evalue=8e-74, Organism=Escherichia coli, GI145693107, Length=268, Percent_Identity=50.3731343283582, Blast_Score=262, Evalue=3e-71, Organism=Escherichia coli, GI1787759, Length=318, Percent_Identity=42.1383647798742, Blast_Score=261, Evalue=5e-71, Organism=Escherichia coli, GI1788506, Length=258, Percent_Identity=46.1240310077519, Blast_Score=232, Evalue=3e-62, Organism=Escherichia coli, GI1787500, Length=318, Percent_Identity=38.0503144654088, Blast_Score=206, Evalue=2e-54, Organism=Escherichia coli, GI1789962, Length=311, Percent_Identity=35.6913183279743, Blast_Score=195, Evalue=3e-51, Organism=Escherichia coli, GI1787758, Length=308, Percent_Identity=36.038961038961, Blast_Score=195, Evalue=3e-51, Organism=Escherichia coli, GI1789890, Length=234, Percent_Identity=36.3247863247863, Blast_Score=149, Evalue=4e-37, Organism=Escherichia coli, GI48994997, Length=257, Percent_Identity=35.408560311284, Blast_Score=146, Evalue=1e-36, Organism=Escherichia coli, GI1787547, Length=261, Percent_Identity=32.5670498084291, Blast_Score=138, Evalue=4e-34, Organism=Escherichia coli, GI1789891, Length=240, Percent_Identity=36.6666666666667, Blast_Score=135, Evalue=4e-33, Organism=Escherichia coli, GI1789032, Length=232, Percent_Identity=34.4827586206897, Blast_Score=120, Evalue=9e-29, Organism=Escherichia coli, GI1787029, Length=253, Percent_Identity=31.2252964426877, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1788225, Length=234, Percent_Identity=35.042735042735, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI1786398, Length=286, Percent_Identity=29.7202797202797, Blast_Score=113, Evalue=2e-26, Organism=Escherichia coli, GI1787089, Length=244, Percent_Identity=34.4262295081967, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1786703, Length=211, Percent_Identity=35.5450236966825, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI87081834, Length=223, Percent_Identity=33.1838565022422, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1789672, Length=254, Percent_Identity=29.9212598425197, Blast_Score=101, Evalue=7e-23, Organism=Escherichia coli, GI1787712, Length=251, Percent_Identity=28.6852589641434, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1788644, Length=180, Percent_Identity=31.6666666666667, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI87081791, Length=239, Percent_Identity=29.7071129707113, Blast_Score=93, Evalue=3e-20, Organism=Escherichia coli, GI1790162, Length=259, Percent_Identity=26.2548262548263, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1788761, Length=250, Percent_Identity=29.2, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1789873, Length=216, Percent_Identity=30.5555555555556, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787370, Length=238, Percent_Identity=28.1512605042017, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1786872, Length=223, Percent_Identity=30.4932735426009, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1788450, Length=258, Percent_Identity=24.8062015503876, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1787105, Length=280, Percent_Identity=29.2857142857143, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1786563, Length=232, Percent_Identity=28.8793103448276, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI87081709, Length=252, Percent_Identity=25.3968253968254, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1790467, Length=232, Percent_Identity=29.7413793103448, Blast_Score=78, Evalue=8e-16, Organism=Escherichia coli, GI1787792, Length=222, Percent_Identity=28.3783783783784, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786253, Length=217, Percent_Identity=29.0322580645161, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1789991, Length=219, Percent_Identity=24.6575342465753, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI87082267, Length=231, Percent_Identity=25.974025974026, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI1787164, Length=231, Percent_Identity=28.1385281385281, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786319, Length=229, Percent_Identity=28.3842794759825, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786345, Length=236, Percent_Identity=26.271186440678, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786803, Length=250, Percent_Identity=25.6, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI48994943, Length=233, Percent_Identity=27.4678111587983, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1790544, Length=249, Percent_Identity=25.7028112449799, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1788053, Length=194, Percent_Identity=27.8350515463918, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI48995001, Length=221, Percent_Identity=27.6018099547511, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1788002, Length=230, Percent_Identity=25.6521739130435, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1786698, Length=218, Percent_Identity=27.0642201834862, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1789586, Length=222, Percent_Identity=27.9279279279279, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1790190, Length=249, Percent_Identity=26.1044176706827, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI193209708, Length=243, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI212646699, Length=225, Percent_Identity=29.7777777777778, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI25146777, Length=233, Percent_Identity=28.755364806867, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115534520, Length=227, Percent_Identity=27.3127753303965, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17552232, Length=250, Percent_Identity=28.8, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193208177, Length=239, Percent_Identity=27.6150627615063, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17558664, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17569143, Length=254, Percent_Identity=29.5275590551181, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193202349, Length=220, Percent_Identity=28.6363636363636, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71984940, Length=216, Percent_Identity=28.2407407407407, Blast_Score=65, Evalue=7e-11, Organism=Caenorhabditis elegans, GI71992290, Length=255, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322980, Length=269, Percent_Identity=27.1375464684015, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6324985, Length=260, Percent_Identity=25.3846153846154, Blast_Score=70, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6323217, Length=250, Percent_Identity=28.8, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6319856, Length=224, Percent_Identity=26.7857142857143, Blast_Score=63, Evalue=5e-11, Organism=Drosophila melanogaster, GI24641565, Length=219, Percent_Identity=31.9634703196347, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI28574150, Length=217, Percent_Identity=24.4239631336406, Blast_Score=69, Evalue=6e-12, Organism=Drosophila melanogaster, GI116007328, Length=217, Percent_Identity=24.4239631336406, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28574744, Length=232, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DPPD_ECO57 (P0AAG1)
Other databases:
- EMBL: AE005174 - EMBL: BA000007 - PIR: A86028 - PIR: E91181 - RefSeq: NP_290122.1 - RefSeq: NP_312448.1 - ProteinModelPortal: P0AAG1 - SMR: P0AAG1 - EnsemblBacteria: EBESCT00000027130 - EnsemblBacteria: EBESCT00000057993 - GeneID: 915714 - GeneID: 961077 - GenomeReviews: AE005174_GR - GenomeReviews: BA000007_GR - KEGG: ece:Z4958 - KEGG: ecs:ECs4421 - GeneTree: EBGT00070000031696 - HOGENOM: HBG758042 - OMA: RKENMAL - ProtClustDB: PRK11022 - BioCyc: ECOL83334:ECS4421-MONOMER - InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 - SMART: SM00382 - TIGRFAMs: TIGR01727
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY
EC number: NA
Molecular weight: Translated: 35845; Mature: 35714
Theoretical pI: Translated: 6.60; Mature: 6.60
Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 5.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYP CCEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHEEEEEEECCC GRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQ CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHC GGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEP CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCC TTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHA CCEEEEEHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHEEEEECCCEEECCCCEE IFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAE EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCC EPALNMLADGRQSKCHYPLDDAGRPTL CCHHHHHHCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure ALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYP CEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHEEEEEEECCC GRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQ CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHC GGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEP CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCC TTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHA CCEEEEEHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHEEEEECCCEEECCCCEE IFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAE EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCC EPALNMLADGRQSKCHYPLDDAGRPTL CCHHHHHHCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; dipeptides [Periplasm]; H2O [C]
Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796