Click here to switch to the map view.

The map label for this gene is agaA

Identifier: 218696842

GI number: 218696842

Start: 3637743

End: 3638897

Strand: Direct

Name: agaA

Synonym: EC55989_3555

Alternate gene names: 218696842

Gene position: 3637743-3638897 (Clockwise)

Preceding gene: 218696841

Following gene: 218696843

Centisome position: 70.57

GC content: 57.75

Gene sequence:

>1155_bases
ATGTCCGGTCGAGGAAGGGATATGACACACGTTCTGCGCGCCAGAAGGCTGCTGACTGAAGAGGGATGGCTCGATGACCA
TCAGTTGCGTATTGCTGACGGTGTCATCGCAGCAATCGAACCGATTCCAGTGGGCGTGACTGAACGCGATGCGGAACTGC
TCTGCCCCGCTTACATCGACACCCATGTACACGGTGGTGCGGGCGTTGATGTAATGGATGACGCGCCGGATGTGCTCGAC
AAGCTGGCAATGCACAAGGCACGCGAAGGTGTCGGCAGTTGGTTACCGACTACCGTAACCGCGCCGCTTAATACCATTCA
TGCGGCGCTGAAACGTATTGCGCAACGTTGCCAACGCGGCGGACCTGGTGCGCAAGTGCTGGGGAGTTATCTCGAAGGAC
CGTACTTCACGCCGCAGAATAAAGGCGCGCATCCGCCGGAGTTGTTTCGCGAGCTTGAAATTGCCGAGCTGGATCAATTG
ATTGCCGTTTCTCAGCACACCTTACGCGTGGTAGCGCTGGCACCGGAAAAAGAGGGGGCATTGCAGGCCATCCGCCATCT
TAAACAGCAAAATGTACGAGTGATGCTGGGGCATAGCGCGGCGACCTGGCAACAAACTCGCGCCGCGTTTGATGCTGGTG
CCGACGGCCTGGTGCATTGCTATAACGGGATGACAGGTTTACATCACCGCGAACCGGGAATGGTTGGCGCGGGATTAACG
GACAAGCGCGCCTGGCTGGAACTGATAGCCGATGGTCATCATGTGCATCCGGCGGCGATGTCGCTGTGTTGTTGCTGTGC
AAAAGAGAGAATCGTGCTGATCACCGACGCGATGCAGGCAGCCGGGATGCCGGATGGTCGCTATACGTTATGTGGCGAAG
AAGTGCAGATGCACGGTGGCGTTGTCCGTACCGCGTCCGGTGGGCTGGCGGGCAGTACGCTGTCTGTTGATGCGGCAGTG
CGCAACATGGTCGAGTTGACGGGCGTAACGCCTGCGGAAGCCATTCATATGGCATCGCTGCATCCGGCGCGAATGCTGGG
TGTTGATGGTGTTCTGGGATCGCTTAAACCGGGCAAACGCGCCAGCGTCGTTGCGCTGGATAGCGGGCTACATGTGCAAC
AAATCTGGATTCAGGGTCAATTAGCTTCGTTTTGA

Upstream 100 bases:

>100_bases
GCGAAGGGTTAAGCGGTGAAGAATTCCGTGTACAGGCACTGGAGTGTGGACATCGTGGGCTGACCAGTCTGGTGGACGAG
TTAGGCCGCTGCCATGAAGA

Downstream 100 bases:

>100_bases
TGGTTTGCTCCATTATTGGGCCTTCACTTCCCCCGTAAGGCCTTTCTTTTTCTTTCTTTTTGATCTGTGCAGCGGTGTCG
GATGCGACGCTAACGCGTCT

Product: N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase)

Products: D-Galactosamine 6-Phosphate; Acetate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSGRGRDMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYIDTHVHGGAGVDVMDDAPDVLD
KLAMHKAREGVGSWLPTTVTAPLNTIHAALKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQL
IAVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAV
RNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF

Sequences:

>Translated_384_residues
MSGRGRDMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYIDTHVHGGAGVDVMDDAPDVLD
KLAMHKAREGVGSWLPTTVTAPLNTIHAALKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQL
IAVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAV
RNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF
>Mature_383_residues
SGRGRDMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYIDTHVHGGAGVDVMDDAPDVLDK
LAMHKAREGVGSWLPTTVTAPLNTIHAALKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLI
AVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLTD
KRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAVR
NMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF

Specific function: N-acetylgalactosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=415, Percent_Identity=33.4939759036145, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI224922791, Length=415, Percent_Identity=33.2530120481928, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI1786892, Length=380, Percent_Identity=32.3684210526316, Blast_Score=181, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17553768, Length=387, Percent_Identity=29.7157622739018, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI19920392, Length=389, Percent_Identity=30.8483290488432, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281361140, Length=402, Percent_Identity=30.5970149253731, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: 3.5.1.- [C]

Molecular weight: Translated: 41028; Mature: 40897

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRGRDMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYID
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEECCCCCCCCCCCHHHCCHHHHH
THVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTAPLNTIHAALKRIAQRCQRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGA
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCEEEEEEECCCCCHH
LQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCEECCCC
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGRYTLCGEEVQMHGG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCEEEECCHHHHCCC
VVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKR
EEEECCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCHHHCCCCCCCC
ASVVALDSGLHVQQIWIQGQLASF
EEEEEECCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
SGRGRDMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYID
CCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEECCCCCCCCCCCHHHCCHHHHH
THVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTAPLNTIHAALKRIAQRCQRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGA
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCEEEEEEECCCCCHH
LQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCEECCCC
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGRYTLCGEEVQMHGG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCEEEECCHHHHCCC
VVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKR
EEEECCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCHHHCCCCCCCC
ASVVALDSGLHVQQIWIQGQLASF
EEEEEECCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Acetyl-D-Galactosamine 6-Phosphate; H2O [C]

Specific reaction: N-Acetyl-D-Galactosamine 6-Phosphate + H2O = D-Galactosamine 6-Phosphate + Acetate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]