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The map label for this gene is uxaC

Identifier: 218696796

GI number: 218696796

Start: 3591618

End: 3593030

Strand: Reverse

Name: uxaC

Synonym: EC55989_3506

Alternate gene names: 218696796

Gene position: 3593030-3591618 (Counterclockwise)

Preceding gene: 218696798

Following gene: 218696795

Centisome position: 69.7

GC content: 54.21

Gene sequence:

>1413_bases
ATGACTCCGTTTATGACTGAAGATTTCCTGTTAGATACCGAATTTGCCCGCCGTCTGTATCACGACTACGCAAAAGACCA
GCCGATTTTCGATTACCATTGCCATTTGCCGCCGCAGCAGATTGCGGAAGACTATCGTTTTAAAAACCTGTATGACATCT
GGCTGAAAGGCGATCACTACAAATGGCGCGCTATGCGTACCAACGGTGTGGCCGAGCGTCTGTGTACCGGTGATGCGTCT
GACCGTGAAAAATTTGACGCCTGGGCGGCGACTGTTCCGCACACTATCGGCAACCCGTTATACCACTGGACGCACCTCGA
ACTGCGTCGTCCGTTTGGTATCACTGGCAAATTGCTTTCTCCGTCAACTGCCGATGAAATCTGGAACGAATGTAACGAAC
TGCTGGCGCAGGATAACTTCTCCGCGCGCGGCATCATGCAGCAGATGAACGTGAAAATGGTCGGCACCACCGATGACCCG
ATCGATTCTCTGGAGCATCACGCAGAGATCGCCAAAGACGGCTCTTTCACCATCAAAGTGCTGCCGAGCTGGCGTCCGGA
CAAAGCCTTCAACATCGAACAGGCGACCTTTAACGACTACATGGCGAAGCTGGGCGAAGTTTCCGATACCGACATTCGCC
GCTTTGCTGACCTGCAAACTGCCTTGACCAAACGTCTGGATCACTTCGCCGCTCACGGCTGTAAAGTGTCTGACCATGCG
CTGGACGTGGTGATGTTTGCTGAAGCGAACGAAGCGGAACTGGACAGCATTCTGGCGCGCCGTCTGGCTGGCGAACCCCT
GAGCGAGCACGAAGTGGCACAGTTCAAAACTGCGGTACTGGTGTTCCTTGGTGCCGAATATGCACGTCGCGGCTGGGTAC
AGCAGTACCACATTGGCGCGCTGCGTAATAACAACCTGCGTCAGTTCAAACTGCTGGGGCCGGATGTAGGCTTTGACTCC
ATCAACGACCGTCCGATGGCGGAAGAGTTGTCTAAGCTGCTGAGCAAGCAGAACGAAGAAAACCTGCTGCCGAAAACCAT
TCTCTACTGCCTGAACCCGCGCGATAACGAAGTGCTGGGCACCATGATCGGTAACTTCCAGGGCGAAGGTATGCCGGGCA
AAATGCAGTTCGGTTCCGGCTGGTGGTTTAACGATCAGAAAGACGGTATGGAACGTCAGATGACCCAACTGGCGCAGCTC
GGTCTGCTGAGCCGCTTTGTCGGTATGCTGACTGACAGCCGTAGCTTCCTGTCATACACCCGTCACGAATACTTCCGCCG
CATTCTGTGCCAGATGATCGGTCGCTGGGTGGAAGCGGGCGAAGCACCGGCGGACATCAACCTGCTGGGCGAGATGGTGA
AAAATATTTGCTTTAACAATGCGCGTGACTACTTCGCCATTGAACTGAACTAA

Upstream 100 bases:

>100_bases
TAACTCACGAAAATATCTTCGGACTCTGGAAATTGGTGTGATAACTTTGTCAGCATCGCACCATAAGCAAGCTAGCTCAC
TCGTTGAGAGGAAGACGAAA

Downstream 100 bases:

>100_bases
GGTCTGGGGTTGATATGCAATACATCAAGATCCATGCGCTGGATAACGTCGCGGTCGCTTTAGCAGATTTGGCTGAAGGC
ACAGAAGTCAGTGTCGATAA

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDAS
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHA
LDVVMFAEANEAELDSILARRLAGEPLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDS
INDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN

Sequences:

>Translated_470_residues
MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDAS
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHA
LDVVMFAEANEAELDSILARRLAGEPLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDS
INDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
>Mature_469_residues
TPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASD
REKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPI
DSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHAL
DVVMFAEANEAELDSILARRLAGEPLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSI
NDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLG
LLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=470, Percent_Identity=99.7872340425532, Blast_Score=984, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53984; Mature: 53853

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHY
CCCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCEEEEEECCCCE
KWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLS
EEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKV
CCHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEE
LPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHA
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LDVVMFAEANEAELDSILARRLAGEPLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGA
EEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLG
HCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCHHHH
TMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYT
HHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure 
TPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHY
CCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCEEEEEECCCCE
KWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLS
EEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKV
CCHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEE
LPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHA
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LDVVMFAEANEAELDSILARRLAGEPLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGA
EEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLG
HCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCHHHH
TMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYT
HHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA