Click here to switch to the map view.

The map label for this gene is ttdA

Identifier: 218696766

GI number: 218696766

Start: 3555197

End: 3556108

Strand: Direct

Name: ttdA

Synonym: EC55989_3476

Alternate gene names: 218696766

Gene position: 3555197-3556108 (Clockwise)

Preceding gene: 218696764

Following gene: 218696767

Centisome position: 68.97

GC content: 53.95

Gene sequence:

>912_bases
ATGATGAGCGAAAGTAATAAGCAACAGGCAGTGAATAAGTTGACAGAGATTGTCGCTAACTTTACCGCCATGATTTCTAC
CCGAATGCCTGATGACGTGGTGGATAAACTAAAACAGCTAAAGGATGCCGAAACGTCGTCGATGGGGAAAATTATCTACC
ATACGATGTTCGACAACATGCAAAAAGCGATTGACCTGAATCGTCCTGCCTGTCAGGACACCGGGGAGATTATGTTCTTC
GTTAAAGTCGGTTCCCGCTTCCCACTGCTTGGCGAGCTGCAAAGCATACTCAAACAAGCCGTGGAAGAGGCAACCGTCAA
AGCGCCACTACGTCACAATGCGGTAGAAATTTTTGACGAAGTAAACACCGGCAAAAATACCGGTAGCGGCGTACCGTGGG
TCACCTGGGACATCATCCCCGACAATGACGATGCGGAAATCGAAGTTTACATGGCAGGCGGCGGCTGCACGCTACCTGGC
CGCTCGAAAGTGTTAATGCCGTCAGAAGGCTACGAAGGCGTGGTGAAATTCGTCTTCGAAAATATCTCCACCCTCGCCGT
AAACGCCTGTCCACCGGTACTGGTGGGCGTGGGCATCGCCACCTCGGTGGAAACCGCCGCCGTACTCTCGCGTAAAGCCA
TTTTGCGTCCGATTGGCAGCCGCCATCCCAATCCAAAAGCGGCAGAGCTGGAGCTACGCCTGGAAGAAGGACTCAACCGT
CTGGGGATTGGTCCACAAGGGCTGACCGGCAACAGTTCAGTGATGGGCGTGCATATCGAATCTGCCGCCCGCCATCCGTC
AACCATCGGCGTTGCTGTCTCTACCGGCTGCTGGGCGCATCGTCGCGGCACGCTGCTGGTTCATGCCGATCTCACCTTTG
AAAATCTGTCTCACACCCGGAGCGCGTTATGA

Upstream 100 bases:

>100_bases
TTAATTACATATTCACGGTGGCAAAAAATATAAAACCACATTTTTAGTGGTAGTTTGTGGCGGTGAATTTTTCCAGACAA
ATACAAAAACTGGAGTTGCC

Downstream 100 bases:

>100_bases
AAAAGATCCTGACAACCCCGATCAAAGCTGAAGATCTGCAAGATATTCGCGTCGGCGATGTGATCTACCTGACCGGTACG
CTGGTGACCTGCCGCGACGT

Product: tartrate dehydratase subunit alpha

Products: NA

Alternate protein names: L-TTD alpha [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFF
VKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLLVHADLTFENLSHTRSAL

Sequences:

>Translated_303_residues
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFF
VKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLLVHADLTFENLSHTRSAL
>Mature_303_residues
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFF
VKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLLVHADLTFENLSHTRSAL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=303, Percent_Identity=100, Blast_Score=626, Evalue=0.0,
Organism=Escherichia coli, GI1790564, Length=258, Percent_Identity=26.7441860465116, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 32734; Mature: 32734

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNM
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDE
HHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHH
VNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPGRSKVLMPSEGYEGVVKFVFE
HCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHH
NISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
HHHHEEECCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHCHHH
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLLVHADLTFENLSHTR
HCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCEEECCCCEEEEECCCHHHHHHHH
SAL
HCC
>Mature Secondary Structure
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNM
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDE
HHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHH
VNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPGRSKVLMPSEGYEGVVKFVFE
HCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHH
NISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
HHHHEEECCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHCHHH
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLLVHADLTFENLSHTR
HCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCEEECCCCEEEEECCCHHHHHHHH
SAL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]