Click here to switch to the map view.

The map label for this gene is cpdA

Identifier: 218696738

GI number: 218696738

Start: 3526096

End: 3526923

Strand: Reverse

Name: cpdA

Synonym: EC55989_3448

Alternate gene names: 218696738

Gene position: 3526923-3526096 (Counterclockwise)

Preceding gene: 218696739

Following gene: 218696737

Centisome position: 68.42

GC content: 56.16

Gene sequence:

>828_bases
TTGGAAAGCCTGTTAACCCTTCCTCTGGCTGGTGAGGCCAGAGTCAGGATTTTACAAATTACCGATACTCACCTGTTTGC
ACAAAAGCACGAAGCCCTGTTAGGGGTAAACACCTGGGAAAGCTACCAGGCGGTGCTGGAGGCGATTCGTCCACATCAGC
ACGAATTCGACCTGATTGTCGCGACAGGTGATTTAGCGCAGGATCAATCCTCTGCGGCCTATCAGCATTTCGCTGAAGGC
ATCGCAAGTTTTCGTGCGCCCTGCGTCTGGCTGCCGGGCAACCACGATTTCCAGCCCGCGATGTACAGCGCGTTACAGGA
TGCGGGTATCTCCCCGGCGAAGCGCGTGTTTATTGGTGAGCAATGGCAAATCCTGTTGCTGGATAGCCAGGTGTTTGGCG
TGCCGCACGGTGAGCTGAGCGAGTTTCAGCTTGAGTGGCTGGAACGTAAACTGGCCGATGCGCCAGAACGCCATACGTTG
CTGCTGCTGCATCATCATCCGCTACCTGCGGGTTGTAGTTGGCTCGATCAACACAGTCTGCGTAACGCGGGCGAACTGGA
TACCGTGCTGGCGAAGTTTCCGCACGTCAAATACTTGCTGTGCGGTCATATTCATCAGGAGCTGGATCTCGACTGGAACG
GTCGCCGCCTGCTGGCAACGCCGTCGACCTGTGTGCAGTTTAAGCCGCACTGTTCCAACTTTACGCTGGATACTATCGCG
CCCGGCTGGCGTACTCTCGAGTTACATGCTGATGGCACGCTGACCACCGAGGTGCATCGCCTGGCGGACACACGTTTCCA
ACCTGATACCGCTTCAGAAGGCTACTGA

Upstream 100 bases:

>100_bases
TCAAATTAACCAGTTTTTAGCGGACTGGTTGCGATACTGTTTAGCACATGGAGCGATGGCGATTCCGGTTTACTAGCGTC
GTGAAACCTAAGGACACCAT

Downstream 100 bases:

>100_bases
TGTCTACGCTTCTTTATTTACACGGTTTCAACAGCTCGCCGCGCTCTGCAAAAGCGAGCTTGTTAAAAAACTGGCTGGCG
GAACATCACCCTGACGTTGA

Product: cyclic 3',5'-adenosine monophosphate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG
IASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY

Sequences:

>Translated_275_residues
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG
IASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>Mature_275_residues
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG
IASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY

Specific function: Affects the expression of the lacZ gene

COG id: COG1409

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789410, Length=275, Percent_Identity=100, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ICC_ECO57 (P0AEW5)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   G85963
- PIR:   H91118
- RefSeq:   NP_289612.1
- RefSeq:   NP_311947.1
- ProteinModelPortal:   P0AEW5
- SMR:   P0AEW5
- EnsemblBacteria:   EBESCT00000029032
- EnsemblBacteria:   EBESCT00000059491
- GeneID:   916255
- GeneID:   958507
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4389
- KEGG:   ecs:ECs3920
- GeneTree:   EBGT00050000011548
- HOGENOM:   HBG285602
- OMA:   CAWLDQH
- ProtClustDB:   PRK11148
- BioCyc:   ECOL83334:ECS3920-MONOMER
- InterPro:   IPR013622
- InterPro:   IPR004843
- ProDom:   PD587589

Pfam domain/function: PF00149 Metallophos; PF08413 Metallophos_C

EC number: NA

Molecular weight: Translated: 30938; Mature: 30938

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
CCCEEEECCCCCCEEEEEEEECHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCEEEEE
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
EECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHEEEECC
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
CEEEEEEECEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHC
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
CCCCHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCHHEEECCCCCCEEECCCC
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
CCCEEEECCCCCCEEEEEEEECHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCEEEEE
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
EECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHEEEECC
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
CEEEEEEECEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHC
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
CCCCHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCHHEEECCCCCCEEECCCC
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796