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The map label for this gene is qseB

Identifier: 218696731

GI number: 218696731

Start: 3519918

End: 3520577

Strand: Direct

Name: qseB

Synonym: EC55989_3441

Alternate gene names: 218696731

Gene position: 3519918-3520577 (Clockwise)

Preceding gene: 218696723

Following gene: 218696732

Centisome position: 68.28

GC content: 51.97

Gene sequence:

>660_bases
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Upstream 100 bases:

>100_bases
TAACAACTTCTTAAGGGAAAAAAATAAAATTTAGTGCTGTACAGAGCGCGTTACAACACGGTTTACTGGCAGCAAATACG
GTTATCGCAGGGATGAAAAA

Downstream 100 bases:

>100_bases
AATTTACCCAACGTCTTAGTCTGCGCGTCAGGCTGACGCTAATCTTTTTAATTCTGGCCTCGGTGACCTGGCTGCTTTCC
AGCTTTGTCGCCTGGAAACA

Product: DNA-binding transcriptional regulator QseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Sequences:

>Translated_219_residues
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK
>Mature_219_residues
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=99.0867579908676, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=46.2962962962963, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=40.8071748878924, Blast_Score=163, Evalue=7e-42,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=37.2727272727273, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=34.8623853211009, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=35.1351351351351, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=34.2222222222222, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=33.6363636363636, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.6491228070175, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=30.8370044052863, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=27.3542600896861, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.6943231441048, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=29.2035398230088, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=128, Percent_Identity=33.59375, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): QSEB_ECO57 (Q8XBS3)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C85962
- PIR:   C91117
- RefSeq:   NP_289600.1
- RefSeq:   NP_311934.1
- ProteinModelPortal:   Q8XBS3
- SMR:   Q8XBS3
- EnsemblBacteria:   EBESCT00000028880
- EnsemblBacteria:   EBESCT00000059986
- GeneID:   916262
- GeneID:   958498
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4377
- KEGG:   ecs:ECs3907
- GeneTree:   EBGT00070000031686
- HOGENOM:   HBG753323
- OMA:   FSIDWFT
- ProtClustDB:   PRK10336
- BioCyc:   ECOL83334:ECS3907-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 24746; Mature: 24746

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGR
CEEEEEECCEEECCCHHHHHHHHCCCEEHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCH
DILREWREKGQREPVLILTARDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTN
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLELLMRNAGRVLPRKLIEEKLYT
CCCCCCCCCCCEEECCCCEEEECCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
WDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGR
CEEEEEECCEEECCCHHHHHHHHCCCEEHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCH
DILREWREKGQREPVLILTARDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTN
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLELLMRNAGRVLPRKLIEEKLYT
CCCCCCCCCCCEEECCCCEEEECCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
WDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534