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The map label for this gene is fucU

Identifier: 218696403

GI number: 218696403

Start: 3156201

End: 3156623

Strand: Direct

Name: fucU

Synonym: EC55989_3083

Alternate gene names: 218696403

Gene position: 3156201-3156623 (Clockwise)

Preceding gene: 218696402

Following gene: 218696404

Centisome position: 61.23

GC content: 48.94

Gene sequence:

>423_bases
ATGCTGAAAACAATTTCGCCGTTAATTTCTCCCGAACTATTGAAAGTGCTGGCAGAGATGGGACATGGAGATGAAATTAT
TTTTTCCGATGCTCACTTTCCCGCCCATTCGATGGGACCGCAGGTGATCCGCGCTGATGGCCTGTTGGTGAGCGACTTGC
TCCAGGCGATTATCCCGTTATTTGAACTGGACAGTTATGCACCGCCGCTGGTGATGATGGCGGCGGTAGAAGGTGACACT
CTCGATCCTGAAGTAGAACGACGTTACCGTAATGCGCTTTCACTACAAGCCCCGTGTCCTGACATCATCCGCATCAATCG
TTTTGCGTTTTATGAACGGGCGCAAAAAGCCTTTGCGATCGTTATCACAGGCGAACGAGCGAAGTACGGGAATATTCTTT
TAAAAAAAGGGGTAACACCGTAA

Upstream 100 bases:

>100_bases
GGGGAATTTAACAGCCCGGAAGAAGCCCGCGCACAGATTCATTATCAGTACCGTTATTTCTACCCGCAAACTGAACCTGA
ATTTATAGAGGAAGTGTGAA

Downstream 100 bases:

>100_bases
TCTCATACCGGTACGCCCGCATGACGCGGGCGGTTATCGAATGATGGGGTGAAAAATATGAAAGCGGCACGCCAGCAAGC
GATAGTCGACCTGCTGCTGA

Product: L-fucose mutarotase

Products: NA

Alternate protein names: Fucose 1-epimerase; Type-2 mutarotase [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDT
LDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP

Sequences:

>Translated_140_residues
MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDT
LDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
>Mature_140_residues
MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDT
LDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP

Specific function: Involved in the anomeric conversion of L-fucose [H]

COG id: COG4154

COG function: function code G; Fucose dissimilation pathway protein FucU

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rbsD / fucU family. FucU mutarotase subfamily [H]

Homologues:

Organism=Homo sapiens, GI148596947, Length=144, Percent_Identity=47.9166666666667, Blast_Score=120, Evalue=3e-28,
Organism=Homo sapiens, GI148596951, Length=130, Percent_Identity=46.1538461538462, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1789169, Length=140, Percent_Identity=100, Blast_Score=284, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007721 [H]

Pfam domain/function: PF05025 RbsD_FucU [H]

EC number: NA

Molecular weight: Translated: 15473; Mature: 15473

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPL
CCCCCCHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
FELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAI
HHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEE
VITGERAKYGNILLKKGVTP
EEECCCCCCCCEEEECCCCC
>Mature Secondary Structure
MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPL
CCCCCCHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
FELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAI
HHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEE
VITGERAKYGNILLKKGVTP
EEECCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA