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The map label for this gene is xni

Identifier: 218696397

GI number: 218696397

Start: 3148278

End: 3149123

Strand: Direct

Name: xni

Synonym: EC55989_3077

Alternate gene names: 218696397

Gene position: 3148278-3149123 (Clockwise)

Preceding gene: 218696396

Following gene: 218696400

Centisome position: 61.07

GC content: 52.6

Gene sequence:

>846_bases
TTGCGAGGCCTCTTCCCGATTTCTCATCCAGCCGTAGCCTGTTCCGGCATCGAATGTTACCCTTATCGCCTGATCTTTAA
GGGGGTTATCGTGGCTGTTCATTTGCTTATTGTCGATGCACTGAATCTTATTCGTCGCATTCATGCCGTTCAGGGATCGC
CCTGTGTCGAAACCTGCCAGCATGCGCTCGATCAGCTCATTATGCACAGCCAGCCAACCCACGCGGTCGCCGTTTTTGAT
GATGAAAACCGCAGTAGCGGCTGGCGTCATCAGCGTTTACCAGATTACAAAGCGGGTCGACCGCCAATGCCGGAAGAGTT
GCACGACGAGATGCCTGCATTACGCGCCGCCTTTGAGCAACGCGGCGTCCCGTGCTGGTCAACCAGCGGCAACGAAGCCG
ATGACTTAGCCGCCACGCTGGCGGTCAAAGTGACACAGGCCGGGCATCAGGCAACGATTGTTTCGACAGATAAAGGCTAC
TGTCAGTTACTTTCACCGACATTACGTATTCGTGATTACTTCCAGAAACGTTGGCTGGATGCGCCATTTATCGATAAAGA
ATTTGGCGTTCAACCGCAGCAGTTGCCCGATTACTGGGGACTTGCGGGGATCAGCAGTTCAAAGGTACCGGGTGTTGCGG
GAATCGGACCAAAAAGCGCCACGCAGCTGCTGGTCGAGTTTCAGAGTCTGGAAGGGATATATGAGAATCTGGATGCGGTT
GCCGAAAAGTGGCGCAAAAAATTAGAAACCCATAAAGAGATGGCGTTTCTGTGCCGCGATATTGCCCGCTTACAAACCGA
TTTGCATATCGACGGCAATTTACAGCAATTGCGGTTGGTACGGTAA

Upstream 100 bases:

>100_bases
AACAGGTAAAGATATGAACGCCAAGTACCGCGAAACCTCTCGCGGCGGCCTGGCAATGAAGATCGTTGCCTGCGATTAAT
CGCTCTCCAGAGGCCTCGTT

Downstream 100 bases:

>100_bases
CGGCGAGCCGGATACGCCGCAAACGTCGTATCCGGCATTATCACATCAGCGCATTTACCAGGCGGTATGGTAAAGCTCTA
CAATATCCTCAAGCGTTGCT

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRGLFPISHPAVACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFD
DENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGY
CQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
AEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR

Sequences:

>Translated_281_residues
MRGLFPISHPAVACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFD
DENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGY
CQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
AEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
>Mature_281_residues
MRGLFPISHPAVACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFD
DENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGY
CQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
AEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing [H]

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI226510970, Length=251, Percent_Identity=99.601593625498, Blast_Score=519, Evalue=1e-149,
Organism=Escherichia coli, GI1790294, Length=226, Percent_Identity=32.7433628318584, Blast_Score=131, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895 [H]

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 31455; Mature: 31455

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLFPISHPAVACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQ
CCCCCCCCCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQ
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLD
CCCCCCCCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
APFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
CCCCCHHHCCCCHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECC
>Mature Secondary Structure
MRGLFPISHPAVACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQ
CCCCCCCCCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQ
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLD
CCCCCCCCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
APFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
CCCCCHHHCCCCHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA