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The map label for this gene is rtn

Identifier: 218695791

GI number: 218695791

Start: 2486126

End: 2487682

Strand: Direct

Name: rtn

Synonym: EC55989_2430

Alternate gene names: 218695791

Gene position: 2486126-2487682 (Clockwise)

Preceding gene: 218695790

Following gene: 218695792

Centisome position: 48.23

GC content: 50.29

Gene sequence:

>1557_bases
ATGTTCATACGCGCTCCCAATTCTGGACGTAAGCTCCTGCTTACCTGCATTGTTGCAGGCGTGATGATTGCGATACTGGT
GAGTTGCCTTCAATTTTTAGTGGCCTGGCATAAGCACGAAGTCAAATACGACACACTGATTACCGACGTACAAAAGTATC
TCGATACCTATTTTGCCGACCTGAAATCCACTACTGACCGGCTTCAGCCGCTGACCTTAGATACCTGCCAGCAGGCTAAC
CCCGAACTGACCGCTCGCGCGGCGTTTAGCATGAATGTCCGTACGTTTGTGCTGGTGAAAGATAAAAAAACATTCTGTTC
ATCTGCGACCGGTGAGATGGACATTCCACTCAATGAATTGATTCCGGCGCTCGACATTAATAAAAATGTCGATATGGCGA
TCTTACCCGGCACGCCGATGGTGCCGAACAAACCCGCAATCGTCATCTGGTATCGCAACCCTTTGCTGAAAAATAGCGGC
GTCTTTGCCGCTCTGAATCTCAACCTGACGCCTTCACTCTTTTATAGTTCACGGCAGGAAGATTACGATGGCGTCGCCCT
CATTATTGGCAATACTGCGCTATCTACCTTTTCTTCACGTTTGATGAACGTTAACGAATTAACCGACATGCCAGTCCGTG
AAACTAAAATTGCGGGCATTCCTCTGACCGTTCGGCTTTATGCAGATGACTGGACATGGAACGATGTGTGGTACGCATTT
TTACTGGGCGGCATGAGTGGAACTGTCGTTGGCCTGCTCTGCTATTACCTGATGAGCGTACGTATGCGCCCCGGCAGAGA
AATCATGACCGCCATCAAGCGCGAACAATTTTACGTGGCGTATCAACCGGTGGTGGATACACAAGCTTTGCGAGTAACGG
GCCTGGAAGTACTGCTACGCTGGCGGCATCCTGTCGCGGGAGAAATTCCCCCTGATGCCTTCATTAACTTTGCCGAATCG
CAAAAGATGATTGTGCCGCTGACTCAGCATCTGTTTGAGTTAATTGCCCGCGATGCCGCAGAATTAGAAAAAGTGCTGCC
GGTAGGCGTCAAATTTGGCATTAACATTGCGCCGGACCATCTGCACAGCGAAAGCTTTAAAGCAGATATCCAGAAACTGC
TCACTTCCCTACCCGCACACCATTTCCAGATTGTGCTGGAAATTACCGAGCGCGATATGCTGAAAGAGCAAGAAGCCACA
CAACTCTTCGCCTGGCTGCACTCGGTAGGCGTAGAAATTGCTATTGATGACTTCGGCACCGGGCACAGCGCGCTTATCTA
TCTTGAGCGTTTTACGCTCGATTATCTGAAAATTGACCGTGGATTTATCAACGCCATCGGTACGGAAACGATCACTTCAC
CCGTACTTGACGCGGTGCTGACGCTGGCGAAACGCCTCAATATGCTGACGGTTGCTGAAGGGGTCGAAACGCCGGAACAA
GCGCGATGGCTAAGCGAACGCGGCGTTAATTTCATGCAAGGCTACTGGATTAGTCGCCCGTTACCGCTGGACGATTTTGT
TCGCTGGCTGAAGAAACCGTATACGCCGCAGTGGTAA

Upstream 100 bases:

>100_bases
TTCATCAGAGAAAATGATGTTTCCGCGTCTTGATCCAGGCTATAGTCCGGTCATTGTTATCTTTTAAATGTTGTCGTAAT
TTCAGGAAATTAACGGAATC

Downstream 100 bases:

>100_bases
GGTGTGCTTACGTCCCTTATTATTCATAGTGAAAGCATGCCGGATTGCGGCTAATGATGAGTAAAAGGAAATCCGTTGCA
GATGATTGTGCGCATACTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAES
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW

Sequences:

>Translated_518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAES
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW
>Mature_518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAES
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=518, Percent_Identity=99.8069498069498, Blast_Score=1067, Evalue=0.0,
Organism=Escherichia coli, GI87081980, Length=518, Percent_Identity=28.957528957529, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=39.2857142857143, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=36.8421052631579, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=30.6772908366534, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI87081743, Length=270, Percent_Identity=31.4814814814815, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1787541, Length=246, Percent_Identity=30.4878048780488, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081921, Length=255, Percent_Identity=29.8039215686275, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI226510982, Length=253, Percent_Identity=31.2252964426877, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=28.6885245901639, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=30.0411522633745, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1787055, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787410, Length=226, Percent_Identity=25.2212389380531, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58529; Mature: 58529

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFAD
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNEL
HHHHHHHCCCCCHHHHHCCCCCEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHC
IPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQE
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCC
DYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
CCCCEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHH
LLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLR
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHH
WRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDH
HCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCHH
LHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGT
HCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
CCCEEEEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHH
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFAD
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNEL
HHHHHHHCCCCCHHHHHCCCCCEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHC
IPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQE
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCC
DYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
CCCCEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHH
LLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLR
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHH
WRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDH
HCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCHH
LHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGT
HCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQ
CCCEEEEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHH
ARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]