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The map label for this gene is yegQ

Identifier: 218695705

GI number: 218695705

Start: 2396457

End: 2397818

Strand: Direct

Name: yegQ

Synonym: EC55989_2340

Alternate gene names: 218695705

Gene position: 2396457-2397818 (Clockwise)

Preceding gene: 218695704

Following gene: 218695708

Centisome position: 46.49

GC content: 54.11

Gene sequence:

>1362_bases
ATGTTTAAACCGGAACTCCTTTCCCCGGCGGGAACGCTGAAAAATATGCGTTACGCTTTCGCTTATGGCGCAGATGCTGT
TTATGCGGGCCAGCCGCGTTATTCCCTGCGTGTGCGCAACAACGAATTCAACCACGAAAATCTTCAGCTCGGCATCAATG
AAGCCCACGCGCTGGGGAAAAAGTTTTATGTCGTGGTCAACATTGCACCGCACAACGCCAAGCTGAAAACCTTTATCCGT
GACCTGAAACCGGTGGTGGAAATGGGGCCGGATGCGCTGATTATGTCCGATCCAGGGCTGATTATGCTGGTGCGTGAGCA
CTTCCCTGAAATGCCGATCCACCTTTCGGTGCAGGCTAACGCCGTGAACTGGGCGACGGTGAAATTCTGGCAGCAAATGG
GCCTGACCCGCGTGATCCTCTCTCGCGAGCTGTCGCTGGAAGAGATTGAAGAGATCCGCAATCAGGTGCCGGATATGGAG
ATCGAGATCTTCGTTCACGGCGCGCTGTGCATGGCCTACTCCGGTCGCTGCCTGCTCTCTGGCTATATCAACAAGCGCGA
CCCGAACCAGGGCACCTGCACCAACGCCTGCCGCTGGGAGTACAACGTCCAGGAAGGGAAAGAAGATGATGTTGGCAACA
TCGTACACAAGTACGAGCCGATTCCGGTGCAAAATGTTGAGCCGACGCTGGGTATCGGCGCACCAACCGACAAAGTGTTT
ATGATCGAAGAGGCCCAGCGTCCGGGCGAGTATATGACCGCGTTTGAAGATGAGCACGGCACTTACATCATGAACTCGAA
AGATCTGCGCGCCATCGCCCATGTAGAACGCCTGACCAAAATGGGCGTGCATTCGCTGAAAATCGAAGGTCGTACCAAAT
CTTTCTACTATTGTGCACGCACCGCACAGGTTTACCGCAAAGCTATCGATGACGCCGCTGCGGGAAAACCGTTCGATACC
AGCCTGCTGGAAACTCTGGAAGGTCTGGCGCATCGTGGCTATACCGAAGGTTTCCTGCGTCGTCATACTCACGACGATTA
TCAGAACTACGAATACGGTTATTCAGTTTCTGACCGCCAGCAGTTTGTTGGTGAGTTTACCGGTGAGCGCAAGGGGGACC
TCGCGGCGGTAGCGGTGAAAAATAAATTCTCCGTTGGCGACAGCCTTGAGCTGATGACGCCGCAAGGCAACATTAATTTT
ACCCTTGAGCACATGGAAAACGCCAAAGGCGAAGCTATGCCGATAGCACCAGGCGATGGTTATACTGTGTGGCTCCCGGT
CCCGCAGGATCTTGAGCTCAATTACGCGCTGCTGATGCGTAATTTCTCCGGGGAAACCACGCGTAATCCCCACGGTAAGT
GA

Upstream 100 bases:

>100_bases
CCGCCGATTGCGCTACAATGCCCGCCCTTAAAGTGGGGGCACTCCCCTAACCGCTTCATCAGGTGAAGCGGATCTGACCT
GTCATCAGAACGAGAGAATT

Downstream 100 bases:

>100_bases
TTAATTTCGATTATTTTTCCCGGATGGAAAATTCTTAGAAACCGATCACATACAGCTGTATTTATTAAGGTTATCATCCG
TTTCGCTGAAAAACATAACC

Product: putative peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIR
DLKPVVEMGPDALIMSDPGLIMLVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKYEPIPVQNVEPTLGIGAPTDKVF
MIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVERLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDT
SLLETLEGLAHRGYTEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELMTPQGNINF
TLEHMENAKGEAMPIAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNPHGK

Sequences:

>Translated_453_residues
MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIR
DLKPVVEMGPDALIMSDPGLIMLVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKYEPIPVQNVEPTLGIGAPTDKVF
MIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVERLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDT
SLLETLEGLAHRGYTEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELMTPQGNINF
TLEHMENAKGEAMPIAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNPHGK
>Mature_453_residues
MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIR
DLKPVVEMGPDALIMSDPGLIMLVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKYEPIPVQNVEPTLGIGAPTDKVF
MIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVERLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDT
SLLETLEGLAHRGYTEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELMTPQGNINF
TLEHMENAKGEAMPIAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNPHGK

Specific function: Unknown

COG id: COG0826

COG function: function code O; Collagenase and related proteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U32 family

Homologues:

Organism=Escherichia coli, GI1788397, Length=453, Percent_Identity=100, Blast_Score=951, Evalue=0.0,
Organism=Escherichia coli, GI87081910, Length=441, Percent_Identity=29.0249433106576, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789548, Length=321, Percent_Identity=28.9719626168224, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEGQ_ECOLI (P76403)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   H64974
- RefSeq:   AP_002681.1
- RefSeq:   NP_416585.1
- ProteinModelPortal:   P76403
- DIP:   DIP-11887N
- STRING:   P76403
- MEROPS:   U32.002
- EnsemblBacteria:   EBESCT00000000151
- EnsemblBacteria:   EBESCT00000016013
- GeneID:   946609
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2066
- KEGG:   eco:b2081
- EchoBASE:   EB3813
- EcoGene:   EG14060
- eggNOG:   COG0826
- GeneTree:   EBGT00050000010311
- HOGENOM:   HBG463792
- OMA:   DLRAVEH
- ProtClustDB:   PRK15452
- BioCyc:   EcoCyc:G7118-MONOMER
- Genevestigator:   P76403
- GO:   GO:0006508
- InterPro:   IPR001539

Pfam domain/function: PF01136 Peptidase_U32

EC number: 3.4.-.- [C]

Molecular weight: Translated: 51194; Mature: 51194

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS01276 PEPTIDASE_U32

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLQLGINEAHALGK
CCCCCCCCCCHHHHCCEEEEEECCCEEEECCCCEEEEEECCCCCCCCEEEECHHHHHCCC
KFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIMLVREHFPEMPIHLSVQAN
EEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEHHHCCCCCEEEEEEEC
AVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDMEIEIFVHGALCMAYSGRCLLS
CCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEEEHCCCCEEEE
GYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKYEPIPVQNVEPTLGIGAPTDKVF
ECCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
MIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVERLTKMGVHSLKIEGRTKSFYYCAR
EEECCCCCCHHHEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHH
TAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGYTEGFLRRHTHDDYQNYEYGYSVSDRQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHH
QFVGEFTGERKGDLAAVAVKNKFSVGDSLELMTPQGNINFTLEHMENAKGEAMPIAPGDG
HHHHHHCCCCCCCEEEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCEEEECCCCC
YTVWLPVPQDLELNYALLMRNFSGETTRNPHGK
EEEEEECCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLQLGINEAHALGK
CCCCCCCCCCHHHHCCEEEEEECCCEEEECCCCEEEEEECCCCCCCCEEEECHHHHHCCC
KFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIMLVREHFPEMPIHLSVQAN
EEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEHHHCCCCCEEEEEEEC
AVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDMEIEIFVHGALCMAYSGRCLLS
CCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEEEHCCCCEEEE
GYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKYEPIPVQNVEPTLGIGAPTDKVF
ECCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
MIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVERLTKMGVHSLKIEGRTKSFYYCAR
EEECCCCCCHHHEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHH
TAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGYTEGFLRRHTHDDYQNYEYGYSVSDRQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHH
QFVGEFTGERKGDLAAVAVKNKFSVGDSLELMTPQGNINFTLEHMENAKGEAMPIAPGDG
HHHHHHCCCCCCCEEEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCEEEECCCCC
YTVWLPVPQDLELNYALLMRNFSGETTRNPHGK
EEEEEECCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503