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The map label for this gene is rbsK [H]

Identifier: 218695605

GI number: 218695605

Start: 2282496

End: 2283710

Strand: Direct

Name: rbsK [H]

Synonym: EC55989_2232

Alternate gene names: 218695605

Gene position: 2282496-2283710 (Clockwise)

Preceding gene: 218695604

Following gene: 218695606

Centisome position: 44.28

GC content: 41.48

Gene sequence:

>1215_bases
ATGAAATTTGAACGCCATCATGAAATATTGAAACGACTCAGTAAATTCGGTTCTGTAAAAGTATCCGATCTGTCCAATAG
CCTCAATGTAACGAAAGAAACTATTCGTTCAGATCTTAATGAACTTGCCAGGCTTGGCTATCTGACTCGATGTCATGGCG
GTGCTTTTATCGTCCTAGACTCGCTTGATACTATTGCGAAAAATGAAATCGCTTATGCGCTTGAAAATTATGATACAGCC
CAGGGAATAAAAAAAGGCCACTCAACTATGAAAAGTCAAGTATGCGTTATTGGTTCGTTTAATGTTGATATCATCAGTTA
TTTGCCGAGGCTTCCCACTATCGGAGAATCGCTTCTGGCAAGTAATTTTATATTTTCACCGGGGGGAAAAGGCTGTAACC
AGGCGCTGGCAGCAAGCTTTGCCGATACTGATGTTTATTTCATAACAAAAGTAGGTACAGATCACTTTAGTGATTATGCG
ATCAACTTTATGAATTCGTCTAAGATTTATAAAAGTATAATTTATCAAACGAAAGAAACGCAAACCGAAACTGCCACGAT
CCTTGTTAATGAAGGTACTGGCGATAATGTTATTGCGATCTATCCCGGTGCCAACATGACAATGTCGTCCGATGAAATAA
CTATTCAGAAAGAAGCGATTATTAATTCTGATGTCATACTTCTGCAGCTCGAAACAAATTATACCGCTCTGCAACAAGCG
ATCACATTGGCGCAAAAAAACAGTATCCCGGTCATTATTAACCCGGCACCCTATAATGATATCGTCAACGAACTTATTCA
GGATGTTGATTATATCACCCCCAATGAAACAGAAGCTGGTTTACTGTCCGGCATAGACGTACACGATCTTGAATCAGCTA
AACGAGCTGCAGAAGCTATCCACAATAAAGGGGTAAAAAACACGGTTATCACGCTCGGTAGCAAGGGCTCGCTCGCATTT
GATGGCAAAAAATTCATTCATTCGCCAGCGTTTCCAGCGGTCGTTAAAAATACGGCAGGAGCCGGGGATGCGTTTAACGG
CTCTCTGGCATCAGGACTTGCGAAAGGAAAATCACTGGAATCAGCACTGTGTTATGCCAGCGCCTTTGCATCCCTAGCGG
TGGAGACAAGCAATGCTTCCGACATGCCTGAACATGAATCTGTGATACATCGAATTCAGAGTATACATTATCAGCAAACT
ATTTTTACGCATTAA

Upstream 100 bases:

>100_bases
AGGCTATTTTTGCTTTTTTTTGCTTTTCCCCGCCACTTTATGGTGATTATCACATCAATATACATCGATAGATATTAACG
TAACTGCAGTGAGGTGAAGC

Downstream 100 bases:

>100_bases
GAAGGGACAGAGAATGAATAACACCAAAAAATCACTAAAAGTGCTCTTTATTGGGGAATCCTGGCATATTCATATGATTC
ATTCAAAAGGATATGACAGT

Product: putative carbohydrate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELARLGYLTRCHGGAFIVLDSLDTIAKNEIAYALENYDTA
QGIKKGHSTMKSQVCVIGSFNVDIISYLPRLPTIGESLLASNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYA
INFMNSSKIYKSIIYQTKETQTETATILVNEGTGDNVIAIYPGANMTMSSDEITIQKEAIINSDVILLQLETNYTALQQA
ITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNETEAGLLSGIDVHDLESAKRAAEAIHNKGVKNTVITLGSKGSLAF
DGKKFIHSPAFPAVVKNTAGAGDAFNGSLASGLAKGKSLESALCYASAFASLAVETSNASDMPEHESVIHRIQSIHYQQT
IFTH

Sequences:

>Translated_404_residues
MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELARLGYLTRCHGGAFIVLDSLDTIAKNEIAYALENYDTA
QGIKKGHSTMKSQVCVIGSFNVDIISYLPRLPTIGESLLASNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYA
INFMNSSKIYKSIIYQTKETQTETATILVNEGTGDNVIAIYPGANMTMSSDEITIQKEAIINSDVILLQLETNYTALQQA
ITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNETEAGLLSGIDVHDLESAKRAAEAIHNKGVKNTVITLGSKGSLAF
DGKKFIHSPAFPAVVKNTAGAGDAFNGSLASGLAKGKSLESALCYASAFASLAVETSNASDMPEHESVIHRIQSIHYQQT
IFTH
>Mature_404_residues
MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELARLGYLTRCHGGAFIVLDSLDTIAKNEIAYALENYDTA
QGIKKGHSTMKSQVCVIGSFNVDIISYLPRLPTIGESLLASNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYA
INFMNSSKIYKSIIYQTKETQTETATILVNEGTGDNVIAIYPGANMTMSSDEITIQKEAIINSDVILLQLETNYTALQQA
ITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNETEAGLLSGIDVHDLESAKRAAEAIHNKGVKNTVITLGSKGSLAF
DGKKFIHSPAFPAVVKNTAGAGDAFNGSLASGLAKGKSLESALCYASAFASLAVETSNASDMPEHESVIHRIQSIHYQQT
IFTH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=285, Percent_Identity=31.5789473684211, Blast_Score=133, Evalue=3e-31,
Organism=Escherichia coli, GI1790193, Length=266, Percent_Identity=37.593984962406, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788491, Length=304, Percent_Identity=25.6578947368421, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082343, Length=280, Percent_Identity=26.4285714285714, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788017, Length=258, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=35.3333333333333, Blast_Score=144, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=27.8787878787879, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20128807, Length=296, Percent_Identity=34.7972972972973, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24583886, Length=276, Percent_Identity=30.7971014492754, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 43754; Mature: 43754

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELARLGYLTRCHGGAFIVLD
CCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEE
SLDTIAKNEIAYALENYDTAQGIKKGHSTMKSQVCVIGSFNVDIISYLPRLPTIGESLLA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCCHHHHHH
SNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYAINFMNSSKIYKSIIYQTKET
CCCEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCC
QTETATILVNEGTGDNVIAIYPGANMTMSSDEITIQKEAIINSDVILLQLETNYTALQQA
CCCEEEEEEECCCCCCEEEEECCCCCEECCCCEEEEHHHCCCCCEEEEEEECCHHHHHHH
ITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNETEAGLLSGIDVHDLESAKRAAEAI
HHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHH
HNKGVKNTVITLGSKGSLAFDGKKFIHSPAFPAVVKNTAGAGDAFNGSLASGLAKGKSLE
HHCCCCCEEEEECCCCCEEECCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHCCCCHH
SALCYASAFASLAVETSNASDMPEHESVIHRIQSIHYQQTIFTH
HHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELARLGYLTRCHGGAFIVLD
CCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEE
SLDTIAKNEIAYALENYDTAQGIKKGHSTMKSQVCVIGSFNVDIISYLPRLPTIGESLLA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCCHHHHHH
SNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYAINFMNSSKIYKSIIYQTKET
CCCEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCC
QTETATILVNEGTGDNVIAIYPGANMTMSSDEITIQKEAIINSDVILLQLETNYTALQQA
CCCEEEEEEECCCCCCEEEEECCCCCEECCCCEEEEHHHCCCCCEEEEEEECCHHHHHHH
ITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNETEAGLLSGIDVHDLESAKRAAEAI
HHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHH
HNKGVKNTVITLGSKGSLAFDGKKFIHSPAFPAVVKNTAGAGDAFNGSLASGLAKGKSLE
HHCCCCCEEEEECCCCCEEECCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHCCCCHH
SALCYASAFASLAVETSNASDMPEHESVIHRIQSIHYQQTIFTH
HHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]