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The map label for this gene is kdgR

Identifier: 218695393

GI number: 218695393

Start: 2060500

End: 2061282

Strand: Reverse

Name: kdgR

Synonym: EC55989_2004

Alternate gene names: 218695393

Gene position: 2061282-2060500 (Counterclockwise)

Preceding gene: 218695395

Following gene: 218695389

Centisome position: 39.99

GC content: 48.91

Gene sequence:

>783_bases
ATGGCTAACGCAGATCTGGATAAACAGCCTGATTCTGTATCTTCCGTGCTAAAAGTTTTTGGCATTTTGCAGGCGCTGGG
TGAAGAGCGCGAAATAGGGATAACCGAGCTGTCGCAGCGCGTCATGATGTCAAAAAGCACCGTTTATCGCTTTTTACAGA
CCATGAAAACCTTAGGTTATGTGGCGCAGGAAGGGGAGTCGGAGAAATATTCCCTGACCCTGAAATTGTTTGAACTGGGC
GCTCGCGCGTTACAAAACGTCGATTTAATTCGTAGCGCAGATATCCAGATGCGTGAGATCTCCCGCCTGACCAAAGAAAC
TATCCACCTCGGCGCACTGGACGAAGACAGTATTGTTTACATTCACAAAATTGACTCTATGTACAATTTGCGCATGTATT
CACGGATTGGGCGTCGTAATCCGCTGTACAGCACCGCGATTGGTAAGGTACTGCTGGCATGGCGCGATCTCGATGAAGTG
AAGCAAATTCTTGAGGGCGTGGAGTATAAACGCAGTACCGAGCGGACCATCACCAGTACAGAAGCGTTATTACCCGTTCT
GGACCAGGTGCGCGAGCAGGGGTATGGCGAAGATAACGAAGAGCAGGAAGAAGGGCTGCGATGCATTGCGGTACCGGTAT
TTGATCGCTTTGGCGTGGTCATTGCCGGTTTGAGCATCTCCTTCCCGACGTTGCGTTTCTCTGGTAATGACTCCAACTTA
TTGATAGTGTTTTATGTTCAGATAATGCCCGATGACTTTGTCATGCAGCTCCACCGATTTTGA

Upstream 100 bases:

>100_bases
TTGTAACTAACCGGCAAAAGATGGATTGCGACCACCCTGGTGCGAAATTATAATAAAAAACAGTTCTGATTTTTATAAAA
CACTCGCAATGAGGTGATAA

Downstream 100 bases:

>100_bases
GAACGACAGCGACTTCCGTCCCAGCCGTGCCAGGTGCTGCCTCAGATTCAGGTTATGCCGCTCAATTCGCTGCGTATATC
GCTTGCTGATTACGTGCAGC

Product: DNA-binding transcriptional repressor KdgR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELG
ARALQNVDLIRSADIQMREISRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDLDEV
KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSGNDSNL
LIVFYVQIMPDDFVMQLHRF

Sequences:

>Translated_260_residues
MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELG
ARALQNVDLIRSADIQMREISRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDLDEV
KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSGNDSNL
LIVFYVQIMPDDFVMQLHRF
>Mature_259_residues
ANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGA
RALQNVDLIRSADIQMREISRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDLDEVK
QILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSGNDSNLL
IVFYVQIMPDDFVMQLHRF

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=234, Percent_Identity=99.1452991452991, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1786468, Length=221, Percent_Identity=43.8914027149321, Blast_Score=173, Evalue=9e-45,
Organism=Escherichia coli, GI1789999, Length=212, Percent_Identity=35.377358490566, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082359, Length=225, Percent_Identity=29.3333333333333, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790752, Length=202, Percent_Identity=32.1782178217822, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786715, Length=201, Percent_Identity=29.8507462686567, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788581, Length=184, Percent_Identity=32.0652173913043, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29644; Mature: 29512

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISRLTKETIHLGALDEDSIVY
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEE
IHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDLDEVKQILEGVEYKRSTERTITST
EEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSGNDSNL
HHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEHHHHHHHHHHCCCEEECCEEEECCCCCCE
LIVFYVQIMPDDFVMQLHRF
EEEEEEEECCHHHHHHHHCC
>Mature Secondary Structure 
ANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISRLTKETIHLGALDEDSIVY
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEE
IHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDLDEVKQILEGVEYKRSTERTITST
EEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSGNDSNL
HHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEHHHHHHHHHHCCCEEECCEEEECCCCCCE
LIVFYVQIMPDDFVMQLHRF
EEEEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]