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The map label for this gene is ydjL

Identifier: 218695335

GI number: 218695335

Start: 2008686

End: 2009762

Strand: Reverse

Name: ydjL

Synonym: EC55989_1945

Alternate gene names: 218695335

Gene position: 2009762-2008686 (Counterclockwise)

Preceding gene: 218695336

Following gene: 218695334

Centisome position: 38.99

GC content: 49.86

Gene sequence:

>1077_bases
ATGAAAGCACTGGCTCGGTTTGGCAAGGCCTTTGGCGGCTACAAGATGATTGATGTCCCACAACCCATTTGTGGCCCGGA
AGACGTAGTGATTGAAATTAAAGCCGCGGCAATCTGCGGCGCAGACATGAAGCACTACAATGTCGATAGCGGTTCTGATG
AGTTTAACTCTATCCGCGGCCATGAGTTCGCAGGTTGTATTGCGCAGGTTGGTGAAAAAGTCAAAGACTGGAAAGTGGGG
CAACGCGTCGTGTCGGATAACAGCGGTCACGTTTGCGGCGTTTGTCCGGCCTGTGAACAGGGTGATTTTCTGTGTTGTAC
AGAAAAAGTAAACCTTGGTCTGGATAACAATACCTGGGGCGGTGGTTTTTCCAAATATTGTCTGGTTCCTGGTGAAATTC
TCAAAATTCATCGTCATGCGTTGTGGGAAATCCCTGATGGTGTTGATTATGAGGACGCAGCCGTACTTGACCCTATCTGT
AATGCCTATAAATCCATCGCGCAGCAATCGAAATTCCTTCCTGGTCAGGATGTTGTCGTCATCGGCACTGGCCCACTCGG
GCTGTTTTCCGTACAAATGGCGCGGATTATGGGGGCGGTAAATATCGTCGTCGTTGGTCTGCAAGAAGATGTGGCGGTCC
GCTTCCCGGTTGCAAAAGAACTGGGGGCGACGGCAGTAGTAAATGGTTCTACCGAAGATGTGGTGGCGCGCTGCCAGCAA
ATTTGTGGCAAAGATAATCTGGGACTGGTGATTGAATGCTCCGGTGCCAATATCGCACTGAAACAAGCCATCGAAATGCT
CCGCCCGAATGGGGAAGTGGTACGCGTTGGAATGGGCTTCAAACCTCTTGATTTCTCGATTAATGACATTACCGCCTGGA
ATAAAAGCATCATTGGGCATATGGCCTATGACTCCACCTCATGGCGTAACGCTATCCGGCTATTAGCCAGCGGCGCTATC
AAAGTCAAACCGATGATCACGCATCGTATCGGCCTGTCGCAATGGCGCGAAGGGTTTGATGCGATGGTCGATAAAACCGC
AATCAAAGTGATCATGACTTACGACTTTGATGAATAA

Upstream 100 bases:

>100_bases
AGATCATTATCTGTGTTTTACAGATTTAATGTTGACCTCAAAAATCATGTGGGTAAGTATGATGGCCATCTAAGCAAAAC
AAAACACAGAGGATGACGCA

Downstream 100 bases:

>100_bases
CTACTCTCCTGAAGGAACGTTATCGCATGGAACAGATAACAAAACCGCATTGTGGTGCACGGCTGGATCGCTTACCGGAT
TGCCGCTGGCATTCGTCAAT

Product: putative oxidoreductase, Zn-dependent and NAD(P)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMKHYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVG
QRVVSDNSGHVCGVCPACEQGDFLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNGSTEDVVARCQQ
ICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAI
KVKPMITHRIGLSQWREGFDAMVDKTAIKVIMTYDFDE

Sequences:

>Translated_358_residues
MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMKHYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVG
QRVVSDNSGHVCGVCPACEQGDFLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNGSTEDVVARCQQ
ICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAI
KVKPMITHRIGLSQWREGFDAMVDKTAIKVIMTYDFDE
>Mature_358_residues
MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMKHYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVG
QRVVSDNSGHVCGVCPACEQGDFLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNGSTEDVVARCQQ
ICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAI
KVKPMITHRIGLSQWREGFDAMVDKTAIKVIMTYDFDE

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=357, Percent_Identity=27.4509803921569, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI1788075, Length=358, Percent_Identity=99.7206703910614, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=366, Percent_Identity=30.8743169398907, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788073, Length=339, Percent_Identity=28.3185840707965, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI226510992, Length=340, Percent_Identity=27.3529411764706, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787863, Length=340, Percent_Identity=27.9411764705882, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788407, Length=312, Percent_Identity=25.3205128205128, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082125, Length=364, Percent_Identity=27.1978021978022, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790718, Length=333, Percent_Identity=25.5255255255255, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786825, Length=381, Percent_Identity=25.4593175853018, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081918, Length=305, Percent_Identity=25.9016393442623, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786552, Length=356, Percent_Identity=24.438202247191, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=345, Percent_Identity=26.3768115942029, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17562878, Length=335, Percent_Identity=25.0746268656716, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988145, Length=276, Percent_Identity=27.1739130434783, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562584, Length=323, Percent_Identity=28.1733746130031, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323099, Length=340, Percent_Identity=30.2941176470588, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319955, Length=336, Percent_Identity=30.0595238095238, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322619, Length=336, Percent_Identity=30.0595238095238, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319257, Length=395, Percent_Identity=28.1012658227848, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319258, Length=391, Percent_Identity=25.5754475703325, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319621, Length=334, Percent_Identity=28.4431137724551, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=342, Percent_Identity=25.1461988304094, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=342, Percent_Identity=25.7309941520468, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=343, Percent_Identity=26.8221574344023, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737897, Length=351, Percent_Identity=30.7692307692308, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137530, Length=335, Percent_Identity=29.5522388059701, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI45551930, Length=330, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221457811, Length=330, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550770, Length=330, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38714; Mature: 38714

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMKHYNVDSGSDEFNSIRG
CCHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEEEHEEECCCCCCCCCCCCCCHHHHCCC
HEFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGDFLCCTEKVNLGLDNNTWG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECEEECCCCCCCCC
GGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPICNAYKSIAQQSKFLPGQDVVV
CCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNGSTEDVVARCQQ
EECCCHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCHHHCCCEEEECCCHHHHHHHHHH
ICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGH
HHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHEE
MAYDSTSWRNAIRLLASGAIKVKPMITHRIGLSQWREGFDAMVDKTAIKVIMTYDFDE
EECCCHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHHHHCEEEEEEEECCCC
>Mature Secondary Structure
MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMKHYNVDSGSDEFNSIRG
CCHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEEEHEEECCCCCCCCCCCCCCHHHHCCC
HEFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGDFLCCTEKVNLGLDNNTWG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECEEECCCCCCCCC
GGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPICNAYKSIAQQSKFLPGQDVVV
CCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNGSTEDVVARCQQ
EECCCHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCHHHCCCEEEECCCHHHHHHHHHH
ICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGH
HHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHEE
MAYDSTSWRNAIRLLASGAIKVKPMITHRIGLSQWREGFDAMVDKTAIKVIMTYDFDE
EECCCHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHHHHCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]