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The map label for this gene is selD

Identifier: 218695321

GI number: 218695321

Start: 1995396

End: 1996439

Strand: Reverse

Name: selD

Synonym: EC55989_1931

Alternate gene names: 218695321

Gene position: 1996439-1995396 (Counterclockwise)

Preceding gene: 218695322

Following gene: 218695320

Centisome position: 38.73

GC content: 55.17

Gene sequence:

>1044_bases
ATGAGCGAGAACTCGATTCGTTTGACCCAATACAGCCACGGAGCTGGTTGCGGCTGTAAAATTTCCCCAAAAGTGTTGGA
AACCATCCTGCACAGTGAGCAGGCGAAGTTTGTTGATCCGAATTTGCTTGTGGGTAATGAGACCCGCGACGATGCGGCGG
TGTACGATCTGGGCAATGGCACCAGCGTTATCAGTACCACCGACTTCTTTATGCCGATCGTTGATAATCCTTTCGATTTT
GGCCGCATTGCGGCGACTAACGCCATCAGCGATATCTTCGCGATGGGGGGCAAACCGATTATGGCGATTGCGATCCTCGG
CTGGCCGATTAACAAACTTTCCCCGGAAATTGCCCGCGAAGTAACCGAAGGTGGACGCTATGCATGCCGTCAGGCGGGTA
TTGCGCTGGCTGGCGGTCACTCCATCGATGCGCCGGAGCCGATTTTTGGTCTGGCGGTAACGGGGATCGTACCGACCGAG
CGGGTGAAGAAAAACAGTACCGCACAAGCCGGATGCAAACTGTTCCTGACGAAACCGCTGGGGATCGGCGTTCTTACCAC
GGCTGAGAAAAAATCACTGTTGAAACCAGAACATCAGGGACTGGCGACGGAAGTGATGTGCCGGATGAACATCGCAGGTG
CGTCCTTTGCCAACATCGAAGGCGTAAAAGCGATGACCGACGTTACTGGTTTTGGTCTGCTGGGCCATTTGAGCGAAATG
TGTCAGGGCGCAGGTGTGCAGGCGCGCGTTGACTATGACGCGATCCCAAAATTGCCGGGGGTTGAAGAGTACATTAAGTT
GGGCGCAGTGCCTGGCGGCACCGAACGTAACTTTGCCAGCTACGGTCATCTGATGGGTGAAATGCCGCGTGAAGTGCGCG
ATCTGCTGTGCGATCCGCAAACTTCTGGCGGTTTGCTGCTGGCGGTCATGCCGGAAGCAGAAAATGAGGTTAAAACTACA
GCCGCCGAGTTTGGCATTGAACTGACGGCGATTGGCGAACTGGTGCCAGCGCGCGGCGGTCGTGCCATGGTTGAGATCCG
TTAA

Upstream 100 bases:

>100_bases
GTCTGGATTGTGAGCAAAGGCGCAGGAATTCAGACACTCTCACTTATCACTTCACGGAATGAGGGTTACCATACCCGGAT
TGCATTGACAGGAGATGTCC

Downstream 100 bases:

>100_bases
TTCAATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGCGCGCGCCATTGCTGATGTCCTGCCCAAACCGCACCGTAAAG
GCGATGGCTTTATCGAGTGC

Product: selenophosphate synthetase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDF
GRIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEM
CQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKTT
AAEFGIELTAIGELVPARGGRAMVEIR

Sequences:

>Translated_347_residues
MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDF
GRIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEM
CQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKTT
AAEFGIELTAIGELVPARGGRAMVEIR
>Mature_346_residues
SENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFG
RIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTER
VKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEMC
QGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKTTA
AEFGIELTAIGELVPARGGRAMVEIR

Specific function: Synthesizes selenophosphate from selenide and ATP

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily

Homologues:

Organism=Homo sapiens, GI24797148, Length=338, Percent_Identity=29.585798816568, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI15011844, Length=354, Percent_Identity=29.6610169491525, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788062, Length=347, Percent_Identity=99.4236311239193, Blast_Score=705, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17543426, Length=345, Percent_Identity=29.8550724637681, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24653602, Length=265, Percent_Identity=30.188679245283, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653604, Length=265, Percent_Identity=30.188679245283, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28574119, Length=327, Percent_Identity=28.7461773700306, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28574118, Length=267, Percent_Identity=30.3370786516854, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELD_ECO24 (A7ZMN3)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001463062.1
- ProteinModelPortal:   A7ZMN3
- SMR:   A7ZMN3
- STRING:   A7ZMN3
- EnsemblBacteria:   EBESCT00000022167
- GeneID:   5590441
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_1987
- eggNOG:   COG0709
- GeneTree:   EBGT00050000011423
- HOGENOM:   HBG383791
- OMA:   HKLARAS
- ProtClustDB:   PRK00943
- BioCyc:   ECOL331111:ECE24377A_1987-MONOMER
- HAMAP:   MF_00625
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061
- PIRSF:   PIRSF036407
- TIGRFAMs:   TIGR00476

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =2.7.9.3

Molecular weight: Translated: 36704; Mature: 36573

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: ACT_SITE 17-17

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNG
CCCCCEEEEEECCCCCCCCEECHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEECCCC
TSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIARE
CEEEEECCEEHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCHHHHHH
VTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTERVKKNSTAQAGCKLFLTKPL
HHHCCHHHHHHCCEEEECCCCCCCCCCCCCEEEECCCCHHHHHCCCCHHCCEEEEEECCC
GIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEM
CCEEEECHHHHHHCCCHHCCHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
CQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQ
HHCCCCEEEECHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCC
TSGGLLLAVMPEAENEVKTTAAEFGIELTAIGELVPARGGRAMVEIR
CCCCEEEEECCCCCCHHHHHHHHHCEEEEEHHHHHCCCCCEEEEEEC
>Mature Secondary Structure 
SENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNG
CCCCEEEEEECCCCCCCCEECHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEECCCC
TSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIARE
CEEEEECCEEHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCHHHHHH
VTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTERVKKNSTAQAGCKLFLTKPL
HHHCCHHHHHHCCEEEECCCCCCCCCCCCCEEEECCCCHHHHHCCCCHHCCEEEEEECCC
GIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEM
CCEEEECHHHHHHCCCHHCCHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
CQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQ
HHCCCCEEEECHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCC
TSGGLLLAVMPEAENEVKTTAAEFGIELTAIGELVPARGGRAMVEIR
CCCCEEEEECCCCCCHHHHHHHHHCEEEEEHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA