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The map label for this gene is dhaL

Identifier: 218694713

GI number: 218694713

Start: 1344959

End: 1345591

Strand: Reverse

Name: dhaL

Synonym: EC55989_1295

Alternate gene names: 218694713

Gene position: 1345591-1344959 (Counterclockwise)

Preceding gene: 218694714

Following gene: 218694712

Centisome position: 26.1

GC content: 53.4

Gene sequence:

>633_bases
ATGTCACTGAGCAGAACTCAAATTGTTAACTGGCTCACTCGTTGTGGCGATATTTTCAGCACCGAGAGCGAGTATCTTAC
CGGACTGGATCGCGAAATTGGCGACGCTGACCACGGGCTAAATATGAACCGAGGCTTTAGCAAAGTGGTGGAAAAACTCC
CTGCTATCGCAGATAAAGATATCGGTTTCATTCTCAAGAATACCGGTATGACGCTGCTTTCCAGCGTCGGTGGTGCCAGT
GGTCCGCTGTTCGGTACCTTCTTTATCCGCGCCGCACAGGCGACCCAGGCACGGCAAAGCCTGACACTGGAAGAGCTTTA
TCAGATGTTCCGCGATGGCGTGGACGGCGTAATCAGTCGCGGGAAAGCCGAACCTGGCGATAAAACCATGTGTGATGTGT
GGGTGCCGGTGGTGGAATCGTTACGTCAGTCCAGCGAGCAAAATCTCTCTGTTCCGGTGGCGCTCGAAGCTGCCAGTAGA
ATCGCCGAATCCGCTGCACAAAGTACGATTACGATGCAAGCCCGCAAAGGCCGCGCCAGTTATCTCGGTGAACGCAGTAT
TGGTCACCAGGATCCCGGCGCGACCTCGGTGATGTTTATGATGCAAATGTTGGCGTTAGCCGCAAAAGAGTAA

Upstream 100 bases:

>100_bases
TTCTCAATCACCTTACTGAAAGTTGATGACGAAACGCTGGCACTCTGGGACGCCCCGGTCCACACCCCGGCCCTTAACTG
GGGTAAATAAGGAGAAAGCA

Downstream 100 bases:

>100_bases
GGAATTGGTGATGGTAAACCTGGTCATAGTTTCACATAGCAGCCGACTGGGAGAAGGTGTCGGTGAATTAGCCCGTCAGA
TGTTAATGAGTGATAGTTGT

Product: dihydroxyacetone kinase subunit DhaL

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNRGFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGAS
GPLFGTFFIRAAQATQARQSLTLEELYQMFRDGVDGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASR
IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE

Sequences:

>Translated_210_residues
MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNRGFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGAS
GPLFGTFFIRAAQATQARQSLTLEELYQMFRDGVDGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASR
IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE
>Mature_209_residues
SLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNRGFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASG
PLFGTFFIRAAQATQARQSLTLEELYQMFRDGVDGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASRI
AESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=182, Percent_Identity=32.967032967033, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787449, Length=210, Percent_Identity=99.0476190476191, Blast_Score=429, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6323570, Length=201, Percent_Identity=25.3731343283582, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 22729; Mature: 22598

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNRGFSKVVEKLPAIADKD
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
IGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQSLTLEELYQMFRDGVDGVISR
CHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHC
GKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASRIAESAAQSTITMQARKGRAS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YLGERSIGHQDPGATSVMFMMQMLALAAKE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNRGFSKVVEKLPAIADKD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
IGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQSLTLEELYQMFRDGVDGVISR
CHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHC
GKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASRIAESAAQSTITMQARKGRAS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YLGERSIGHQDPGATSVMFMMQMLALAAKE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]