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The map label for this gene is yliI

Identifier: 218694311

GI number: 218694311

Start: 940117

End: 941232

Strand: Direct

Name: yliI

Synonym: EC55989_0882

Alternate gene names: 218694311

Gene position: 940117-941232 (Clockwise)

Preceding gene: 218694310

Following gene: 218694313

Centisome position: 18.24

GC content: 51.7

Gene sequence:

>1116_bases
ATGCATCGACAATCCTTTTTCCTTGTGCCCCTTATTTGTCTTTCTTCCGCTCTCTGGGCGGCTCCTGCAACGGTAAATGT
CGAAGTACTGCAAGACAAACTCGACCATCCCTGGGCACTGGCCTTTTTACCCGATAATCACGGTATGTTAATCACTCTGC
GCGGCGGCGAGTTGCGTCACTGGCAAGTAGGAAAAGGATTATCTGCGCCGCTTTCCGGAGTTCCGGACGTTTGGGCGCAC
GGGCAGGGCGGCCTGCTGGACGTGGTTTTAGCGCCTGATTTTGCTCAGTCTCGCCGCATCTGGTTAAGTTATTCCGAAGT
TGGCGATGATGGCAAAGCCGGAACTGCTGTGGGTTATGGCCGCTTAAGTGATGATCTCTCAAAAGTGACCGACTTCCGCA
CCGTCTTCCGCCAGATGCCAAAACTGTCTACCGGCAACCATTTTGGCGGGCGGCTGGTATTCGACGGTAAAGGTTATCTT
TTTATTGCTCTGGGCGAAAACAATCAGCGCCCGACGGCGCAGGATCTGGATAAATTACAGGGCAAACTGGTGCGTCTGAC
CGACCAGGGCGAAATCCCGGATGATAATCCTTTTATAAAGGAATCCGGTGCGCGCGCCGAGATCTGGTCTTATGGCATTC
GTAATCCGCAAGGAATGGCGATGAATCCGTGGAGTAATGCACTGTGGCTGAATGAACATGGCCCGCGCGGTGGTGATGAA
ATTAATATCCCGCAAAAAGGCAAAAACTACGGCTGGCCGCTGGCAACCTGGGGAATCAACTATTCAGGCTTTAAGATACC
GGAAGCGAAAGGGGAGATCGTCGCCGGGACCGAGCAACCTGTTTTTTACTGGAAAGATTCGCCCGCTGTGAGCGGCATGG
CCTTCTATAACAGCGATAAATTCCCCCAGTGGCAGCAAAAATTATTTATAGGCGCGCTGAAAGATAAAGATGTCATTGTG
ATGAGCGTCAACGGCGACAAAGTGACAGAAGATGGCCGTATTTTAACGGACAGAGGGCAGCGAATTCGTGATGTTCGCTC
TGGACCCGACGGTTATTTATACGTTCTCACCGACGAGTCCAGTGGGGAATTACTTAAAGTTAGCCCACGCAATTAG

Upstream 100 bases:

>100_bases
GGAGAAAGCGTCTCCCCCTTCATGTTTAAGTTTTTGTAAAAATGAATTTGTTATCTCCTCCACTGACTACGCTTTAAGCC
AGAGTCAATCCGGAGGCGTT

Downstream 100 bases:

>100_bases
CTAACGGGAATCATCACCACTTTGCGCACTGCGGGGCGTTCAGTGAGTTGCTGATACCAGCGTTGCAGATTTGGACGCGG
TGTCCAGGTCAGGCCAACGT

Product: PQQ-dependent aldose sugar dehydrogenase precursor (asd)

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQVGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRSGPDGYLYVLTDESSGELLKVSPRN

Sequences:

>Translated_371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQVGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRSGPDGYLYVLTDESSGELLKVSPRN
>Mature_371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQVGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRSGPDGYLYVLTDESSGELLKVSPRN

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936953, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI187936955, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI124248546, Length=199, Percent_Identity=26.1306532663317, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1787060, Length=371, Percent_Identity=99.4609164420485, Blast_Score=756, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 41069; Mature: 41069

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRH
CCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEE
WQVGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYG
EECCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCEEECC
RLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYLFIALGENNQRPTAQDLDKLQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHC
GKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
CEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCCCCE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDK
ECCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEECCCCCCCEEEEECCCC
FPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRILTDRGQRIRDVRSGPDGYLYVLTDES
CCHHHHHHEEEEECCCCEEEEEECCCEECCCCEEEECCCHHHHHHHCCCCCEEEEEEECC
SGELLKVSPRN
CCCEEEECCCC
>Mature Secondary Structure
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRH
CCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEE
WQVGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYG
EECCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCEEECC
RLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYLFIALGENNQRPTAQDLDKLQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHC
GKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
CEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCCCCE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDK
ECCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEECCCCCCCEEEEECCCC
FPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRILTDRGQRIRDVRSGPDGYLYVLTDES
CCHHHHHHEEEEECCCCEEEEEECCCEECCCCEEEECCCHHHHHHHCCCCCEEEEEEECC
SGELLKVSPRN
CCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]