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The map label for this gene is gmhA

Identifier: 218693706

GI number: 218693706

Start: 276249

End: 276827

Strand: Direct

Name: gmhA

Synonym: EC55989_0246

Alternate gene names: 218693706

Gene position: 276249-276827 (Clockwise)

Preceding gene: 218693704

Following gene: 218693707

Centisome position: 5.36

GC content: 50.78

Gene sequence:

>579_bases
ATGTACCAGGATCTTATTCGTAACGAACTGAACGAAGCGGCGGAAACGCTGGCTAACTTTTTAAAAGATGACGCCAATAT
TCACGCCATTCAGCGCGCGGCGGTCCTGTTAGCAGACAGCTTTAAAGCCGGTGGCAAAGTGCTTTCCTGCGGCAACGGCG
GTTCCCATTGCGACGCTATGCACTTTGCCGAAGAGTTGACCGGTCGCTACCGTGAAAACCGTCCGGGCTACCCGGCGATT
GCTATTTCTGACGTTAGTCATATTTCCTGCGTCGGTAATGATTTCGGTTTCAATGATATTTTCTCCCGCTACGTTGAAGC
GGTAGGTCGCGAAGGCGATGTACTGCTGGGGATCTCCACCTCCGGTAACTCTGCAAACGTGATCAAAGCGATCGCAGCGG
CGCGTGAGAAGGGGATGAAAGTGATCACCCTGACCGGTAAAGACGGCGGTAAAATGGCTGGCACGGCGGATATCGAAATT
CGCGTTCCGCACTTTGGTTATGCCGACCGCATTCAGGAGATTCACATTAAAGTGATCCATATCCTGATCCAGTTAATTGA
AAAAGAGATGGTTAAGTAA

Upstream 100 bases:

>100_bases
TCAAAAAGTCCTGGTCATAGCACCTGCCCGTACTTCTCGCTTTTGGCGGTATCCGGTACACTGCATTTTGTCTATTACAT
TTATGCTGAAGGATATCCTC

Downstream 100 bases:

>100_bases
GTCTGGCGTAGGCCGGATAAGGCGTTTACGCCGCATCCGGCACTTGTGCGCTGATGCCTGATGCGATGCTGACGCGTCTT
ATCATGCCTACAAATCTGTA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK

Sequences:

>Translated_192_residues
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
>Mature_192_residues
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=192, Percent_Identity=100, Blast_Score=392, Evalue=1e-111,
Organism=Escherichia coli, GI1789539, Length=166, Percent_Identity=42.1686746987952, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20815; Mature: 20815

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAM
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHH
HFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGIST
HHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEC
SGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIH
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
ILIQLIEKEMVK
HHHHHHHHHHCC
>Mature Secondary Structure
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAM
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHH
HFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGIST
HHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEC
SGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIH
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
ILIQLIEKEMVK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA