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The map label for this gene is yaaU

Identifier: 218693517

GI number: 218693517

Start: 47734

End: 49065

Strand: Direct

Name: yaaU

Synonym: EC55989_0045

Alternate gene names: 218693517

Gene position: 47734-49065 (Clockwise)

Preceding gene: 218693516

Following gene: 218693518

Centisome position: 0.93

GC content: 53.9

Gene sequence:

>1332_bases
ATGCAACCGTCCAGAAACTTTGACGATCTCAAATTCTCCTCAATTCACCGCCGCATTTTGCTGTGGGGAAGCGGTGGTCC
GTTTCTGGATGGTTATGTACTGGTAATGATTGGCGTGGCGCTGGAGCAACTGACCCCGGCGCTGAAACTGGACGCTGACT
GGATTGGCTTGCTGGGCGCGGGAACGCTCGCCGGGCTGTTCGTTGGCACATCGCTGTTTGGCTATATCTCCGATAAAGTC
GGACGGCGCAAAATGTTCCTCATTGATATCATCGCCATCGGCGTGATATCGGTGGCGACGATGTTTGTTTCATCCCCCGT
CGAACTGTTGGTGATGCGGGTACTTATCGGCATTGTCATCGGTGCAGATTATCCCATCGCCACCTCAATGATCACCGAGT
TCTCCAGTACCCGTCAGCGGGCATTTTCCATCAGCTTTATCGCCGCCATGTGGTATGTCGGCGCGACCTGCGCCGATCTG
GTCGGCTACTGGCTTTATGATGTGGAAGGCGGCTGGCGCTGGATGCTGGGTAGCGCGGCGATCCCCTGTTTGTTGATTTT
GATTGGTCGATTCGAACTGCCTGAATCTCCCCGCTGGTTATTACGCAAAGGGCGAGTAAAAGAGTGCGAAGAGATGATGA
TCAAACTGTTTGGCGAACCGGTGGCTTTCGATGAAGAGCAGCCGCAGCAAACCCGTTTTCGCGATCTGTTTAATCGCCGC
CATTTTCCTTTTGTTCTGTTTGTTGCCGCCATCTGGACCTGCCAGGTGATCCCAATGTTCGCCATTTACACCTTTGGCCC
GCAAATCGTTGGTTTGTTGGGATTGGGGGTTGGCAAAAACGCGGCACTGGGGAACGTGGTGATTAGCCTGTTCTTTATGC
TCGGCTGTATTCCGCCGATGCTGTGGCTAAACACTGCCGGACGGCGTCCATTGTTGATTGGCAGCTTTGCCATGATGACG
CTGGCGCTGGCGGTTTTGGGGCTGATCCCGGATATGGGGATCTGGCTGGTAGTGATGGCCTTTGCGGTGTATGCCTTTTT
CTCTGGCGGGCCGGGTAATTTGCAGTGGCTCTATCCTAATGAACTCTTCCCGACAGATATCCGCGCCTCTGCCGTGGGCG
TGATTATGTCCTTAAGCCGTATTGGCACCATTGTTTCGACCTGGGCACTGCCGATCTTTATCAATAATTACGGTATCAGT
AACACGATGCTAATGGGGGCGGGTATCTCGCTGTTTGGCTTGTTGATTTCCGTAGCGTTTGCCCCGGAGACTCGAGGGAT
GTCACTGGCGCAAACCAGCAATATGACGATCCGCGGGCAGAGAATGGGGTAA

Upstream 100 bases:

>100_bases
TACCCGCGCGGCACCTTTGGTGTGGAGTTCCGTTACGGCTGATGTTGGTTTGATACGTAACGCCGTACTGACTCTCATTG
CAAAAAAACAGGAATAACCC

Downstream 100 bases:

>100_bases
ATTGTTCAGATTTCTCTCTTTTCTGAATCAATATTATTGACTATAAGCCGCGTGAATATATGACTACACTTTGTGGGAAA
ACAAAGGCGTAATCACGCGG

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG

Sequences:

>Translated_443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>Mature_443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

Homologues:

Organism=Homo sapiens, GI24497497, Length=380, Percent_Identity=27.3684210526316, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI90669191, Length=380, Percent_Identity=27.3684210526316, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI24308167, Length=439, Percent_Identity=22.7790432801822, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI31542327, Length=434, Percent_Identity=25.1152073732719, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI24497490, Length=391, Percent_Identity=25.8312020460358, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI166064021, Length=382, Percent_Identity=24.6073298429319, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4507005, Length=414, Percent_Identity=24.3961352657005, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI166197673, Length=366, Percent_Identity=24.8633879781421, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI302148518, Length=425, Percent_Identity=23.2941176470588, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4506999, Length=439, Percent_Identity=23.9179954441913, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI203098995, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI216548223, Length=166, Percent_Identity=29.5180722891566, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21553331, Length=313, Percent_Identity=21.7252396166134, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI7662270, Length=192, Percent_Identity=25.5208333333333, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI73695465, Length=188, Percent_Identity=28.7234042553192, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI23510410, Length=189, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786229, Length=443, Percent_Identity=100, Blast_Score=885, Evalue=0.0,
Organism=Escherichia coli, GI87082159, Length=431, Percent_Identity=34.338747099768, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789312, Length=401, Percent_Identity=25.6857855361596, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789207, Length=404, Percent_Identity=24.7524752475248, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790463, Length=426, Percent_Identity=24.6478873239437, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788074, Length=430, Percent_Identity=24.6511627906977, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788068, Length=464, Percent_Identity=24.7844827586207, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17565976, Length=332, Percent_Identity=26.2048192771084, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565978, Length=332, Percent_Identity=23.7951807228916, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71986689, Length=429, Percent_Identity=24.2424242424242, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193202825, Length=429, Percent_Identity=24.2424242424242, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=407, Percent_Identity=22.3587223587224, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71980582, Length=372, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71980584, Length=372, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543784, Length=405, Percent_Identity=26.1728395061728, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193209824, Length=156, Percent_Identity=32.0512820512821, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212645980, Length=368, Percent_Identity=26.6304347826087, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71986504, Length=422, Percent_Identity=23.4597156398104, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=408, Percent_Identity=22.7941176470588, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321068, Length=429, Percent_Identity=22.1445221445221, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573193, Length=368, Percent_Identity=26.6304347826087, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644782, Length=368, Percent_Identity=26.6304347826087, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644778, Length=450, Percent_Identity=24.2222222222222, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668440, Length=399, Percent_Identity=23.5588972431078, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24668456, Length=397, Percent_Identity=21.6624685138539, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24649618, Length=355, Percent_Identity=22.8169014084507, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221330907, Length=350, Percent_Identity=24.8571428571429, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922616, Length=389, Percent_Identity=24.4215938303342, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652795, Length=411, Percent_Identity=23.3576642335766, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649616, Length=355, Percent_Identity=23.943661971831, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652793, Length=411, Percent_Identity=24.0875912408759, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221457681, Length=431, Percent_Identity=23.8979118329466, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24658792, Length=393, Percent_Identity=24.4274809160305, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24640198, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640196, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640200, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648216, Length=366, Percent_Identity=23.7704918032787, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161078612, Length=436, Percent_Identity=22.7064220183486, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YAAU_ECOLI (P31679)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E64725
- RefSeq:   AP_000709.1
- RefSeq:   NP_414587.1
- ProteinModelPortal:   P31679
- STRING:   P31679
- EnsemblBacteria:   EBESCT00000002066
- EnsemblBacteria:   EBESCT00000016502
- GeneID:   944766
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0044
- KEGG:   eco:b0045
- EchoBASE:   EB1527
- EcoGene:   EG11566
- eggNOG:   COG0477
- GeneTree:   EBGT00050000008817
- HOGENOM:   HBG516586
- OMA:   ELDAQWI
- ProtClustDB:   CLSK879551
- BioCyc:   EcoCyc:YAAU-MONOMER
- Genevestigator:   P31679
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828

Pfam domain/function: PF00083 Sugar_tr; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 48668; Mature: 48668

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x159e184c)-; HASH(0x167659a0)-; HASH(0x16c1f4c0)-; HASH(0x17266a34)-; HASH(0x16bd8f70)-; HASH(0x1698702c)-; HASH(0x16484eb4)-; HASH(0x170c4418)-; HASH(0x158888b0)-; HASH(0x15ce7a5c)-; HASH(0x1594d378)-; HASH(0x1677e218)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGA
CCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHH
GTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHH
IPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRR
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPM
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPN
HHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
ELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCHHHHHHHHHHHC
APETRGMSLAQTSNMTIRGQRMG
CCCCCCCEEEECCCCEEEECCCH
>Mature Secondary Structure
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGA
CCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHH
GTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHH
IPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRR
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPM
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPN
HHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
ELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCHHHHHHHHHHHC
APETRGMSLAQTSNMTIRGQRMG
CCCCCCCEEEECCCCEEEECCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503