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The map label for this gene is rpiR [C]

Identifier: 218692545

GI number: 218692545

Start: 4951202

End: 4952026

Strand: Direct

Name: rpiR [C]

Synonym: ECED1_5003

Alternate gene names: 218692545

Gene position: 4951202-4952026 (Clockwise)

Preceding gene: 218692540

Following gene: 218692546

Centisome position: 95.04

GC content: 52.36

Gene sequence:

>825_bases
ATGTCAGAAAATGAAAACCTGCTGCTGAGACTGCGCCAGAGCGTTGATGGATATAGTCGAACGCAACAGAAACTGGGAGA
GTTTGTACTTAGCGATCCGGCAAAAGTAGTCTACCTGACGATTACCGAACTGGCGCGTGAAAGCGGTACCAGCGAGGCTA
GCGTCACACGTCTGTGCCGAACGCTGGGGTGTAAGGGCTATAACGAATTCAAAATGGCGCTTGCACTCGATCTCCGACAA
GTACAGTCTGTAGAGCACGGCGGTGATGAGATTGACAATGTGGTCAATGAATCAGTGCAAGCACTACAGGACACAGCAAA
ATTACTCGACAGGACCTTGCTGGAAGCAGCCACGCTTGCACTGCATCAGGCTCAGTCAGTGCAGATTTATGGCGTAGCAG
CCAGTGCTATTCTGGGGGAGTATTTACATTACAAACTCCTGCGTCTGGGGAAACCCGCACAATTGTTCAGCGATATGCAT
CGTGCTGCCATGAACGCCACAACACTTAGTAAAAACACGTTCGTGGTGGCGATTTCCAGTTCTGGATCCACGCGCGATCT
GCTGCATGTCGTAAAACTAGCGCGTAAGCAAGGTGTGCGTGTACTGGCGCTGAGTAATACGCCGCGCAGTCCGTTAGCTT
CGCTGAGTGATATTCAACTGGTCGCGGCCAAACCGGAAGGCCCCTTGAGCGCCGGCGCGCTGAATGCCAAGGTGGGAGTT
ATGCTGTTGGTAGAGTTACTCACCACATCGCTGATTGCGCTGGATCATAAGTACAGCGATGTGAGCCAGCAAACTGCCAG
CGCGACCCTACCGCTACTGCTTTAA

Upstream 100 bases:

>100_bases
TCAAAATACAAGAAGTCGATCATACTTTTTTTAAAATGTCTGGCATCAATCCCCTCCTTTCCGCCACACTATCAACAGAT
AAACGCATTAAGGATTTTAC

Downstream 100 bases:

>100_bases
AGATATAAAAAACCGCAAAAGCACTGAGGGATCCCCATGAATCAGCGCTAATAAACCAACACCATATTATGGTCGGTTCT
GGCGAAGTGATTAAGAACGG

Product: putative Transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSENENLLLRLRQSVDGYSRTQQKLGEFVLSDPAKVVYLTITELARESGTSEASVTRLCRTLGCKGYNEFKMALALDLRQ
VQSVEHGGDEIDNVVNESVQALQDTAKLLDRTLLEAATLALHQAQSVQIYGVAASAILGEYLHYKLLRLGKPAQLFSDMH
RAAMNATTLSKNTFVVAISSSGSTRDLLHVVKLARKQGVRVLALSNTPRSPLASLSDIQLVAAKPEGPLSAGALNAKVGV
MLLVELLTTSLIALDHKYSDVSQQTASATLPLLL

Sequences:

>Translated_274_residues
MSENENLLLRLRQSVDGYSRTQQKLGEFVLSDPAKVVYLTITELARESGTSEASVTRLCRTLGCKGYNEFKMALALDLRQ
VQSVEHGGDEIDNVVNESVQALQDTAKLLDRTLLEAATLALHQAQSVQIYGVAASAILGEYLHYKLLRLGKPAQLFSDMH
RAAMNATTLSKNTFVVAISSSGSTRDLLHVVKLARKQGVRVLALSNTPRSPLASLSDIQLVAAKPEGPLSAGALNAKVGV
MLLVELLTTSLIALDHKYSDVSQQTASATLPLLL
>Mature_273_residues
SENENLLLRLRQSVDGYSRTQQKLGEFVLSDPAKVVYLTITELARESGTSEASVTRLCRTLGCKGYNEFKMALALDLRQV
QSVEHGGDEIDNVVNESVQALQDTAKLLDRTLLEAATLALHQAQSVQIYGVAASAILGEYLHYKLLRLGKPAQLFSDMHR
AAMNATTLSKNTFVVAISSSGSTRDLLHVVKLARKQGVRVLALSNTPRSPLASLSDIQLVAAKPEGPLSAGALNAKVGVM
LLVELLTTSLIALDHKYSDVSQQTASATLPLLL

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=273, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788159, Length=260, Percent_Identity=24.6153846153846, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788767, Length=253, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082130, Length=262, Percent_Identity=25.1908396946565, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 29567; Mature: 29436

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENENLLLRLRQSVDGYSRTQQKLGEFVLSDPAKVVYLTITELARESGTSEASVTRLCR
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCCCHHHHHHHHH
TLGCKGYNEFKMALALDLRQVQSVEHGGDEIDNVVNESVQALQDTAKLLDRTLLEAATLA
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHQAQSVQIYGVAASAILGEYLHYKLLRLGKPAQLFSDMHRAAMNATTLSKNTFVVAISS
HHHHCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCEEEEEECC
SGSTRDLLHVVKLARKQGVRVLALSNTPRSPLASLSDIQLVAAKPEGPLSAGALNAKVGV
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCCCCCEEEEECCCCCCCCCCHHHHHHH
MLLVELLTTSLIALDHKYSDVSQQTASATLPLLL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SENENLLLRLRQSVDGYSRTQQKLGEFVLSDPAKVVYLTITELARESGTSEASVTRLCR
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCCCHHHHHHHHH
TLGCKGYNEFKMALALDLRQVQSVEHGGDEIDNVVNESVQALQDTAKLLDRTLLEAATLA
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHQAQSVQIYGVAASAILGEYLHYKLLRLGKPAQLFSDMHRAAMNATTLSKNTFVVAISS
HHHHCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCEEEEEECC
SGSTRDLLHVVKLARKQGVRVLALSNTPRSPLASLSDIQLVAAKPEGPLSAGALNAKVGV
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCCCCCEEEEECCCCCCCCCCHHHHHHH
MLLVELLTTSLIALDHKYSDVSQQTASATLPLLL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]