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The map label for this gene is ywbI [H]

Identifier: 218692356

GI number: 218692356

Start: 4752981

End: 4753865

Strand: Reverse

Name: ywbI [H]

Synonym: ECED1_4792

Alternate gene names: 218692356

Gene position: 4753865-4752981 (Counterclockwise)

Preceding gene: 218692359

Following gene: 218692352

Centisome position: 91.25

GC content: 50.06

Gene sequence:

>885_bases
ATGGATATCAGAACGCTGCGTTATTTTGTCGAAGTCGTGCGCCAGCAAAGCTTCACCCGCGCAGCGGAGAAGTTGTTTGT
CACCCAACCAACTATCAGCAAGATGCTGAAGAATCTCGAAGATGAGCTGAACTGTATATTGTTGATCCGCGATGGTCGTC
GGCTGCTTCTCACTGATACTGGTCGCGTCGTATTTGAGCGCGGGCTGGCTTTACTGGCTGAGTTTCGGCAACTGGAAGCT
GAGCTTAGCGATATCAATCAGCTTAAAACCGGCGTTTTGCGGCTGGGAATCCCGCCGATGGTTGGGATGTTGATGGCCGG
GCCGATTGGCCTTTTTCGCCAGCGTTACCCCGGCGTAGAATTGAAAATTTCGGAGTTTGGTGGTCTGACGGTACAACAAG
CGGTGATGAACGGTGAACTGGATATGGCACTGACAGCCCTGCCAGTAGAAGAAAGCGGCCTGACAACGTTATCGCTGTTT
AGTCATCCACTATGTGTACTGACGCCACATTCAGGTAAATGGCTTGAATGTGATGCCGTCTCACCGGAGACATTGGCGGA
ACATCCTCTACTTATCTATAACGAAGATTTTGCCTTAAGTAAGCAATTGATGAAGTTATTCGATGAACATGGCGTTAAGC
CGAGAATTGCAGTTCGCAGCGGGCAATGGGATTTTCTCGCCGCGATGGTTCAGGCCGGTGTCGGAATAGCCATATTGCCG
GAACCCATTTGCCAGCGATTAGATAAAAACACCTTAAAATGGCTACCGCTGGAAAGCGAACTAAGCTGGAAATTAGGAAT
GATTTGGCGTGAGGGCGTTTACCTTTCCCACTCTGCCCACGCGTGGCTGAGCTGTTGTGAAGGATACTGGTTAACGCCAG
AGTAA

Upstream 100 bases:

>100_bases
AGGATATCCTGAAAATAAAACAGAATGGTAAGTATAGAGAGCGCTCGCCCCTGACTGAAATGAATTAAAATCATTGCAGG
TATAGTCAAAGGGAATAGTT

Downstream 100 bases:

>100_bases
GTCGGGTTGGCGGGCTCGCCCGCCAACCATGCAGATTACTGATTTTCCTCAATCAGCAACGCTTCAAGCAAATCGAGATC
GTGCAGTAATTTTTGCAGCG

Product: putative LuxR family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCILLIRDGRRLLLTDTGRVVFERGLALLAEFRQLEA
ELSDINQLKTGVLRLGIPPMVGMLMAGPIGLFRQRYPGVELKISEFGGLTVQQAVMNGELDMALTALPVEESGLTTLSLF
SHPLCVLTPHSGKWLECDAVSPETLAEHPLLIYNEDFALSKQLMKLFDEHGVKPRIAVRSGQWDFLAAMVQAGVGIAILP
EPICQRLDKNTLKWLPLESELSWKLGMIWREGVYLSHSAHAWLSCCEGYWLTPE

Sequences:

>Translated_294_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCILLIRDGRRLLLTDTGRVVFERGLALLAEFRQLEA
ELSDINQLKTGVLRLGIPPMVGMLMAGPIGLFRQRYPGVELKISEFGGLTVQQAVMNGELDMALTALPVEESGLTTLSLF
SHPLCVLTPHSGKWLECDAVSPETLAEHPLLIYNEDFALSKQLMKLFDEHGVKPRIAVRSGQWDFLAAMVQAGVGIAILP
EPICQRLDKNTLKWLPLESELSWKLGMIWREGVYLSHSAHAWLSCCEGYWLTPE
>Mature_294_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCILLIRDGRRLLLTDTGRVVFERGLALLAEFRQLEA
ELSDINQLKTGVLRLGIPPMVGMLMAGPIGLFRQRYPGVELKISEFGGLTVQQAVMNGELDMALTALPVEESGLTTLSLF
SHPLCVLTPHSGKWLECDAVSPETLAEHPLLIYNEDFALSKQLMKLFDEHGVKPRIAVRSGQWDFLAAMVQAGVGIAILP
EPICQRLDKNTLKWLPLESELSWKLGMIWREGVYLSHSAHAWLSCCEGYWLTPE

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=275, Percent_Identity=28.7272727272727, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787879, Length=267, Percent_Identity=28.4644194756554, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI157672245, Length=268, Percent_Identity=25.3731343283582, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788297, Length=262, Percent_Identity=25.1908396946565, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788887, Length=279, Percent_Identity=26.5232974910394, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=27.1255060728745, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=286, Percent_Identity=24.8251748251748, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=25.085910652921, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789506, Length=289, Percent_Identity=20.7612456747405, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=283, Percent_Identity=23.6749116607774, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786401, Length=250, Percent_Identity=30.8, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=262, Percent_Identity=24.4274809160305, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=240, Percent_Identity=25.4166666666667, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=25.2032520325203, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789639, Length=244, Percent_Identity=26.6393442622951, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=194, Percent_Identity=32.4742268041237, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=258, Percent_Identity=25.1937984496124, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082132, Length=306, Percent_Identity=24.1830065359477, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081978, Length=93, Percent_Identity=36.5591397849462, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1790262, Length=253, Percent_Identity=23.7154150197628, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI145693193, Length=126, Percent_Identity=30.1587301587302, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33105; Mature: 33105

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCILLIRDGRRLLLTDT
CCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCCEEEEEEECCCEEEEECC
GRVVFERGLALLAEFRQLEAELSDINQLKTGVLRLGIPPMVGMLMAGPIGLFRQRYPGVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCCCE
LKISEFGGLTVQQAVMNGELDMALTALPVEESGLTTLSLFSHPLCVLTPHSGKWLECDAV
EEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEHHHHCCEEEEECCCCCEEEECCC
SPETLAEHPLLIYNEDFALSKQLMKLFDEHGVKPRIAVRSGQWDFLAAMVQAGVGIAILP
CHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEECC
EPICQRLDKNTLKWLPLESELSWKLGMIWREGVYLSHSAHAWLSCCEGYWLTPE
HHHHHHCCCCCEEEEECCCCCCHHEEEEEECCEEEECCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCILLIRDGRRLLLTDT
CCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCCEEEEEEECCCEEEEECC
GRVVFERGLALLAEFRQLEAELSDINQLKTGVLRLGIPPMVGMLMAGPIGLFRQRYPGVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCCCE
LKISEFGGLTVQQAVMNGELDMALTALPVEESGLTTLSLFSHPLCVLTPHSGKWLECDAV
EEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEHHHHCCEEEEECCCCCEEEECCC
SPETLAEHPLLIYNEDFALSKQLMKLFDEHGVKPRIAVRSGQWDFLAAMVQAGVGIAILP
CHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEECC
EPICQRLDKNTLKWLPLESELSWKLGMIWREGVYLSHSAHAWLSCCEGYWLTPE
HHHHHHCCCCCEEEEECCCCCCHHEEEEEECCEEEECCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]