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The map label for this gene is yjbC [H]

Identifier: 218692307

GI number: 218692307

Start: 4694257

End: 4695129

Strand: Direct

Name: yjbC [H]

Synonym: ECED1_4737

Alternate gene names: 218692307

Gene position: 4694257-4695129 (Clockwise)

Preceding gene: 218692298

Following gene: 218692310

Centisome position: 90.11

GC content: 50.4

Gene sequence:

>873_bases
ATGCTGCCCGACTCATCAGTCCGTTTAAATAAATACATCAGCGAAAGCGGAATTTGCTCACGCCGCGAAGCGGATCGCTA
TATCGAGCAAGGCAATGTGTTCCTTAATGGCAAGCGAGCCACCATTGGCGATCAGGTGAAACCCGGCGACGTTGTGAAAG
TAAATGGTCAGTTGATTGAGCCTCGGGAATCCGAAGATTTGGTACTTATCGCCCTGAACAAGCCCGTCGGTATTGTCAGC
ACCACCGAAGATGGCGAGCGCGATAACATTGTCGATTTCGTTAACCACAGCAAACGCGTGTTCCCGATTGGCCGCCTGGA
TAAAGATTCCCAGGGGCTGATTTTCCTCACCAATCACGGCGATCTGGTGAATAAGATCCTCCGTGCGGGTAACGATCATG
AGAAAGAGTATCTGGTGACGGTTGATAAACCGATTACCGATGAATTTATTCGTGGTATGGGGGCGGGAGTACCGATCCTC
GGGACGGTAACTAAAAAGTGCAAAGTCAAAAAAGAAGCACCGTTTGTCTTCCGCATTACCTTGGTGCAGGGGCTGAACCG
TCAGATTCGTCGCATGTGCGAGCACTTTGGTTACGAAGTGAAAAAGCTGGAACGTACGCGCATTATGAACGTCAGCTTAA
GCGGCATTCCGCTGGGTGAGTGGCGCGATTTAACCGACGATGAGTTAATCGATCTCTTTAAGCTCATTGAAAATTCCTCT
TCCGAGGCAAAACCTAAAGCGAAGGCCAAACCGAAAACGGTAGGCATCAAACGTCCAGTCGTTAAGATGGAAAAAACGGC
GGAAAAAGGCGGTCGCCCGGCGTCCAACGGTAAGCGTTTTACCTCGCCGGGGCGCAAAAAGAAGGGGCGTTAA

Upstream 100 bases:

>100_bases
TAAAAGGCGTGGCAGATCACATTTAATTTCGACGTTGCCGCATAACCCTGTTTTTCCCCGCTAAGAGGTACGGTATATTC
CGCGTTTTACAGGAGAATTT

Downstream 100 bases:

>100_bases
TCAGCGTCTGCCGCGCGTCGACGTATTTGCTGACCAGCTAAATGACGCCTCAGGATCCGGTTTATAAGCCTGCTTTTTCT
TCAATTGGCGGGCTTTTTTC

Product: 23S rRNA pseudouridine synthase F

Products: NA

Alternate protein names: rRNA pseudouridylate synthase F; rRNA-uridine isomerase F [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPRESEDLVLIALNKPVGIVS
TTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSS
SEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR

Sequences:

>Translated_290_residues
MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPRESEDLVLIALNKPVGIVS
TTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSS
SEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR
>Mature_290_residues
MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPRESEDLVLIALNKPVGIVS
TTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSS
SEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR

Specific function: Responsible for synthesis of pseudouridine from uracil- 2604 in 23S ribosomal RNA [H]

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790453, Length=290, Percent_Identity=98.2758620689655, Blast_Score=579, Evalue=1e-167,
Organism=Escherichia coli, GI1787524, Length=283, Percent_Identity=31.8021201413428, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788510, Length=229, Percent_Identity=28.3842794759825, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=29.8913043478261, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 32449; Mature: 32449

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIE
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEECCEEEC
PRESEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHG
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCEEEEECCC
DLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPILGTVTKKCKVKKEAPFVFRIT
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEH
LVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSS
HHHHCCHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
SEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIE
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEECCEEEC
PRESEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHG
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCEEEEECCC
DLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPILGTVTKKCKVKKEAPFVFRIT
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEH
LVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSS
HHHHCCHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
SEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]