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The map label for this gene is sorM [H]

Identifier: 218692301

GI number: 218692301

Start: 4689477

End: 4690331

Strand: Reverse

Name: sorM [H]

Synonym: ECED1_4731

Alternate gene names: 218692301

Gene position: 4690331-4689477 (Counterclockwise)

Preceding gene: 218692302

Following gene: 218692300

Centisome position: 90.03

GC content: 54.15

Gene sequence:

>855_bases
TTGACCAACTTGATGATTAACGGAGCCATCATGGAACAGAGAAAAATTACACGCAGCGATCTGGTGAGCATGTTTCTGCG
CTCCAACCTGCAACAGGCATCCTTTAACTTTGAACGTATTCACGGGCTGGGTTTTTGCTACGACATGATCCCCGCCATCA
AACGACTTTACCCATTAAAAGAGGATCAGGTTGCGGCGCTCAGGCGACACCTGGTGTTCTTCAATACCACGCCAGCCGTA
TGTGGCCCGGTCATCGGCGTCACTGCCGCCATGGAAGAGGCGCGAGCCAACGGCGCGGAAATTGATGACGGTACCATTAA
CGGCATCAAAGTCGGTCTGATGGGACCATTGGCAGGAGTTGGCGATCCACTGGTCTGGGGAACGCTGCGCCCGATTACCG
CCGCGCTCGGCGCATCTCTGGCACTTTCGGGCAACATTCTCGGCCCCCTGCTGTTCTTCTTTATTTTCAACGCGGTGCGT
CTGGCGATGAAGTGGTATGGCCTACAGCTCGGCTTTCGCAAAGGGGTGAATATCGTCAGCGATATGGGCGGTAATTTGCT
GCAAAAACTCACCGAAGGCGCGTCGATTCTCGGGCTGTTTGTGATGGGCGTGCTGGTGACCAAATGGACGTCAATCAACG
TACCGTTGGTGGTTTCACAAACGCCTGCCGCCGATGGTGCCACCGTCACCATAACCGTACAGAACATCCTCGACCAACTT
TGCCCTGGTTTGCTGGCGCTCGGTCTGACGCTGCTGATGGTTCGTCTGCTCAACAAAAAAATTAACCCGGTATGGCTGAT
TTTCGCCCTGTTTGGTTTAGGGATTATCGGTAATGCGCTGGGCTTCCTGTCCTGA

Upstream 100 bases:

>100_bases
TTCGGTGGCGTCGGCGTGATCATGGCCCTGCTCTACATCCAGTTAAATCCACAGTGGCGTAAAGCTGAACCACATCCCCA
GACCACCACTATCACCGCCC

Downstream 100 bases:

>100_bases
TTCTTCGCCCCGGCGCAACCGTCGGGGCCATCGTTCAACATGAGGTGGTTTATGAAAACAACAGCTCTGCGTCTTTATGG
CAAACGTGACCTGCGTCTGG

Product: sorbose permease IID component

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIID-Sor; PTS system sorbose-specific EIID component [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTNLMINGAIMEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRHLVFFNTTPAV
CGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVR
LAMKWYGLQLGFRKGVNIVSDMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGATVTITVQNILDQL
CPGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS

Sequences:

>Translated_284_residues
MTNLMINGAIMEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRHLVFFNTTPAV
CGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVR
LAMKWYGLQLGFRKGVNIVSDMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGATVTITVQNILDQL
CPGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS
>Mature_283_residues
TNLMINGAIMEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRHLVFFNTTPAVC
GPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRL
AMKWYGLQLGFRKGVNIVSDMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGATVTITVQNILDQLC
PGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3716

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIID domain [H]

Homologues:

Organism=Escherichia coli, GI1788122, Length=284, Percent_Identity=60.2112676056338, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI1789529, Length=274, Percent_Identity=36.8613138686131, Blast_Score=157, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004704
- InterPro:   IPR018405 [H]

Pfam domain/function: PF03613 EIID-AGA [H]

EC number: NA

Molecular weight: Translated: 30498; Mature: 30367

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS51108 PTS_EIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLMINGAIMEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLK
CCCEEECHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
EDQVAALRRHLVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGPLAGV
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCC
GDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQLGFRKGVNIVS
CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGATVTITVQNILDQL
HCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHHHHH
CPGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNLMINGAIMEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLK
CCEEECHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
EDQVAALRRHLVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGPLAGV
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCC
GDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQLGFRKGVNIVS
CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGATVTITVQNILDQL
HCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHHHHH
CPGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]