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The map label for this gene is argE [H]

Identifier: 218692243

GI number: 218692243

Start: 4608649

End: 4609800

Strand: Reverse

Name: argE [H]

Synonym: ECED1_4662

Alternate gene names: 218692243

Gene position: 4609800-4608649 (Counterclockwise)

Preceding gene: 218692250

Following gene: 218692242

Centisome position: 88.49

GC content: 52.52

Gene sequence:

>1152_bases
ATGAAAAACAAATTACCGCCATTTATCGAGATTTACCGTGCTCTGATTGCCACACCTTCAATAAGCGCCACGGAAGAGGC
ACTCGATCAAAGCAATGCAGATTTAATCACTCTGCTGGCGGACTGGTTTAAGGATTTAGGCTTCAATGTGGAAGTACAGC
CTGTGCCAGGAACTCGCAACAAATTTAATATGCTGGCCAGTTGCGGACAGGGGGCTGGCGGTTTGTTGCTGGCGGGGCAT
ACCGATACGGTGCCATTTGATGACGGACGCTGGACGCGCGATCCATTTACGTTGACGGAGCATGACGGCAAGCTTTACGG
CTTAGGCACCGCCGACATGAAAGGCTTTTTTGCGTTTATCCTTGATGCGCTACGCGATGTCGACGTCACGAAGCTTGCAA
AACCGCTCTACATTCTGGCGACTGCCGATGAAGAAACCAGTATGGCCGGAGCGCGTTATTTTGCCGAAACTACCGCCCTG
CGCCCGGATTGCGCCATCATTGGCGAGCCAACGTCGCTGCAACCGGTACGCGCGCATAAAGGTCATATCTCTAACGCCAT
CCGTATTCAGGGCCAGTCGGGCCACTCCAGCGATCCAGCACGCGGAGTTAACGCTATCGAACTGATGCACGACGCCATAG
GGCATATTTTGCAATTGCGCGATAACCTGAAAGAACGTTATCACTACGACGCGTTTACCGTGCCATACCCTACGCTCAAC
CTCGGGCATATCCACGGCGGCGATGCATCTAACCGTATTTGCGCTTGTTGTGAGTTGCATATGGATATTCGTCCGCTGCC
AGGCATGACACTCAATGAACTTAACGGTTTGCTCAACGATGCATTGGCTCCAGTGAGCGAACGCTGGCCGGGTCGTCTGA
CGGTCGACGAGCTGCATCCGCCGATCCCTGGCTATGAATGCCCACCGAATCATCAACTGGTTGAAGTGGTTGAGAAATTG
CTCGGAGCAAAGACCGAAGTGGTGAATTACTGTACCGAAGCGCCGTTTATTCAAACGTTATGCCCGACGCTGGTTCTGGG
GCCTGGCTCAATTAATCAGGCTCATCAGCCTGATGAATATCTGGAGACGAGGTTTATCAAGCCCACCCGCGAACTGATCA
CCCAGGTGATTCACCATTTTTGCTGGCATTAA

Upstream 100 bases:

>100_bases
CCTTACGGCTGGTGGGTTTTATTACGCTCAACGTTAGTGTATTTTTATTCATAAATACTGCATGAATATTGATACTATCA
TGACCAGAGGTGTGTCAACA

Downstream 100 bases:

>100_bases
AACGTAGGCCAAACAATGTCGGATGCGATGCTTGCGCATCTTATCCGACCTACACCTTTGGTGTTATTCGAGGCGATTTT
TTAACATTCCCATAAGTTAC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASCGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL
LGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH

Sequences:

>Translated_383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASCGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL
LGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
>Mature_383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASCGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL
LGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=383, Percent_Identity=99.2167101827676, Blast_Score=788, Evalue=0.0,
Organism=Escherichia coli, GI1789236, Length=373, Percent_Identity=27.0777479892761, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788816, Length=259, Percent_Identity=28.957528957529, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17551016, Length=384, Percent_Identity=25.5208333333333, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42267; Mature: 42267

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRN
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCH
KFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFI
HHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHH
LDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHC
GHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLN
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCE
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHP
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHCCC
PIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCHHH
LETRFIKPTRELITQVIHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRN
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCH
KFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFI
HHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHH
LDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHC
GHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLN
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCE
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHP
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHCCC
PIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCHHH
LETRFIKPTRELITQVIHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA