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The map label for this gene is frwD [H]

Identifier: 218692239

GI number: 218692239

Start: 4602375

End: 4602716

Strand: Direct

Name: frwD [H]

Synonym: ECED1_4658

Alternate gene names: 218692239

Gene position: 4602375-4602716 (Clockwise)

Preceding gene: 218692238

Following gene: 218692244

Centisome position: 88.34

GC content: 55.26

Gene sequence:

>342_bases
ATGGCATATCTGGTGGCAGTAACCGCCTGCGTAAGCGGTGTGGCGCATACTTGTATGGCGGCGGAACGGCTGGAAAAGTT
GTGCCAGTTAGAGAAGTGGGGCGTTAGCATTGAAACTCAGGGCGCGTTGGGAACGGAGAATCGTTTAGCGGACGAGGATA
TCCGCCGGGCGGATGTTGCGCTGTTAATTACGGATATCGAGCTTGCCGGTGCTGAGCGATTTGAACATTGTCGCTACGTG
CAATGCAGCATCTACGCTTTCCTGCGTGAGCCGCAGAGGGTGATGAGCGCAGTGCGCAAAGTGCTTTCTGCGCCGCAGCA
AACCCATCTTATTCTGGAGTAG

Upstream 100 bases:

>100_bases
TGGTCGATGAAAGAGGTTTCTGCGCCGTCGTCAGCCGATGTGGCAACGATGCGTGAAATGGCAGAACGGGCCGGATTTCA
GGTTACCGTGGGAGGTTAAA

Downstream 100 bases:

>100_bases
TCGGTTTTTCTGTCAGTTGGCTGTGGTACTGCCGACGATATTCCGACGGCGAGCGTTCGGTATTTTTACGAAACAGACGG
CAGAAGTAGTTGCTGTCGAC

Product: putative fructose-like phosphotransferase EIIB subunit 3

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 3 [H]

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MAYLVAVTACVSGVAHTCMAAERLEKLCQLEKWGVSIETQGALGTENRLADEDIRRADVALLITDIELAGAERFEHCRYV
QCSIYAFLREPQRVMSAVRKVLSAPQQTHLILE

Sequences:

>Translated_113_residues
MAYLVAVTACVSGVAHTCMAAERLEKLCQLEKWGVSIETQGALGTENRLADEDIRRADVALLITDIELAGAERFEHCRYV
QCSIYAFLREPQRVMSAVRKVLSAPQQTHLILE
>Mature_112_residues
AYLVAVTACVSGVAHTCMAAERLEKLCQLEKWGVSIETQGALGTENRLADEDIRRADVALLITDIELAGAERFEHCRYVQ
CSIYAFLREPQRVMSAVRKVLSAPQQTHLILE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790390, Length=113, Percent_Identity=98.2300884955752, Blast_Score=224, Evalue=1e-60,
Organism=Escherichia coli, GI1790387, Length=98, Percent_Identity=42.8571428571429, Blast_Score=84, Evalue=3e-18,
Organism=Escherichia coli, GI87082348, Length=70, Percent_Identity=44.2857142857143, Blast_Score=62, Evalue=6e-12,
Organism=Escherichia coli, GI1788492, Length=65, Percent_Identity=44.6153846153846, Blast_Score=62, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 12592; Mature: 12461

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYLVAVTACVSGVAHTCMAAERLEKLCQLEKWGVSIETQGALGTENRLADEDIRRADVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHH
LLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVLSAPQQTHLILE
HEEEHHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHCEECC
>Mature Secondary Structure 
AYLVAVTACVSGVAHTCMAAERLEKLCQLEKWGVSIETQGALGTENRLADEDIRRADVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHH
LLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVLSAPQQTHLILE
HEEEHHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]