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The map label for this gene is yihW

Identifier: 218692169

GI number: 218692169

Start: 4528764

End: 4529549

Strand: Direct

Name: yihW

Synonym: ECED1_4584

Alternate gene names: 218692169

Gene position: 4528764-4529549 (Clockwise)

Preceding gene: 218692168

Following gene: 218692170

Centisome position: 86.93

GC content: 52.54

Gene sequence:

>786_bases
ATGAGCCTTACCGAACTAACCGGTAACCCGCGGCACGACCAACTCCTCATGCTGATCGCCGAGCGTGGGTATATGAATAT
TGATGAGCTGGCAAATCTGCTGGATGTCTCCACGCAGACGGTCCGCCGGGATATTCGTAAATTAAGCGAGCAAGGACTGA
TTACGCGCCATCACGGTGGCGCGGGTCGGGCTTCCAGCGTCGTTAATACGGCGTTCGAGCAGCGTGAGGTTTCGCAAACC
GAAGAAAAAAAAGCGATTGCCGAAGCGGTGGCAGACTATATTCCTGATGGTTCAACAATATTTATCACCATTGGTACGAC
CGTTGAGCATGTTGCCCGGGCGTTACTTAACCATAACCATTTGCGGATAATCACCAACAGCCTGCGTGTGGCGCATATTC
TTTACCACAACCCGCGCTTTGAAGTGATGGTGCCTGGCGGAACGCTGCGTTCCCATAACAGTGGGATCATTGGCCCTTCA
GCGGCGTCCTTTGTGGCCGATTTTCGCGCCGATTATCTGGTAACAAGTGTAGGCGCAATTGAGAGCGATGGCGCGTTGAT
GGAGTTTGATGTTAACGAAGCTAACGTGGTGAAAACGATGATGGCGCACGCGAGAAATATTCTGCTGGTCGCCGATCACA
CTAAGTATCATGCTTCGGCGGCGGTTGAAATTGGTAATGTGGCACAGGTCACTGCGCTCTTTACCGACGAGCTGCCGCCC
GCTGCGCTAAAATCACGCTTACAAGACAGCCAAATTGAAATCATCCTTCCCCAGGAAGACGCGTAG

Upstream 100 bases:

>100_bases
TCCCGGTGGACGAGCTGGGATCCCTGACTGTGATCAAACCCGATCTTTTTTGTCACTTTTTGTATAAAATGCCAGGGTGA
TGGTTTTTCGAGGAATTTTC

Downstream 100 bases:

>100_bases
AATTTTGTGACCGTTGACCTGGCTTCATACCTGACCACATAGCCAAACCCATCCTTTCCCGCTACAGTTAATTTCTTGTG
GCGCGAAAGGAGGCAAAAAT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDIRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQT
EEKKAIAEAVADYIPDGSTIFITIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAVEIGNVAQVTALFTDELPP
AALKSRLQDSQIEIILPQEDA

Sequences:

>Translated_261_residues
MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDIRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQT
EEKKAIAEAVADYIPDGSTIFITIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAVEIGNVAQVTALFTDELPP
AALKSRLQDSQIEIILPQEDA
>Mature_260_residues
SLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDIRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTE
EKKAIAEAVADYIPDGSTIFITIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPSA
ASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAVEIGNVAQVTALFTDELPPA
ALKSRLQDSQIEIILPQEDA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI87082344, Length=261, Percent_Identity=100, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1789829, Length=246, Percent_Identity=44.7154471544715, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1788069, Length=258, Percent_Identity=25.1937984496124, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=27.1653543307087, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=27.1653543307087, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=28.695652173913, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=26.9230769230769, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787540, Length=247, Percent_Identity=25.1012145748988, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790753, Length=251, Percent_Identity=22.7091633466135, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790635, Length=234, Percent_Identity=23.9316239316239, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YIHW_ECOLI (P32144)

Other databases:

- EMBL:   L19201
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_003924.1
- RefSeq:   NP_418320.2
- ProteinModelPortal:   P32144
- SMR:   P32144
- DIP:   DIP-12504N
- MINT:   MINT-1301395
- STRING:   P32144
- EnsemblBacteria:   EBESCT00000000740
- EnsemblBacteria:   EBESCT00000014843
- GeneID:   948381
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5567
- KEGG:   eco:b3884
- EchoBASE:   EB1795
- EcoGene:   EG11849
- eggNOG:   COG1349
- GeneTree:   EBGT00070000031699
- HOGENOM:   HBG694151
- OMA:   HTKFTAS
- ProtClustDB:   CLSK880808
- BioCyc:   EcoCyc:EG11849-MONOMER
- Genevestigator:   P32144
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 28508; Mature: 28377

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDIRKLSEQGLITRHHGG
CCCCCCCCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
AGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFITIGTTVEHVARALLNHNH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCC
LRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPSAASFVADFRADYLVTSVGAI
EEEEECCCEEEEEEEECCCEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
ESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAVEIGNVAQVTALFTDELPP
CCCCCEEEEECCHHHHHHHHHHHHCCEEEEECCCCHHHHHEEEECCHHHHHHHHHCCCCH
AALKSRLQDSQIEIILPQEDA
HHHHHHCCCCCEEEEECCCCC
>Mature Secondary Structure 
SLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDIRKLSEQGLITRHHGG
CCCCCCCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
AGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFITIGTTVEHVARALLNHNH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCC
LRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPSAASFVADFRADYLVTSVGAI
EEEEECCCEEEEEEEECCCEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
ESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAVEIGNVAQVTALFTDELPP
CCCCCEEEEECCHHHHHHHHHHHHCCEEEEECCCCHHHHHEEEECCHHHHHHHHHCCCCH
AALKSRLQDSQIEIILPQEDA
HHHHHHCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503