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The map label for this gene is rhtC [H]

Identifier: 218692099

GI number: 218692099

Start: 4445321

End: 4445941

Strand: Direct

Name: rhtC [H]

Synonym: ECED1_4508

Alternate gene names: 218692099

Gene position: 4445321-4445941 (Clockwise)

Preceding gene: 218692098

Following gene: 218692101

Centisome position: 85.33

GC content: 51.37

Gene sequence:

>621_bases
ATGTTGATGTTATTCCTCACCGTCGCCATGGTGCACATTGTGGCGCTTATGAGCCCCGGTCCCGATTTCTTTTTTGTCTC
TCAGACCGCTGTTAGTCGTTCCCGTAAAGAAGCGATGATGGGCGTGCTGGGCATTACCTGCGGCGTAATGGTTTGGGCTG
GGATTGCGTTGCTTGGCCTACATTTGATTATCGAAAAAATGGCCTGGCTGCATACGCTGATTATGGTGGGCGGTGGCCTG
TATCTCTGCTGGATGGGTTACCAGATGCTACGCGGTGCACTGAAAAAAGAGGTTGTTTCTGCCCCTGCGCCACAAGTCGA
ACTGGCGAAAAGCGGGCGCAGTTTTCTTAAGGGCTTACTGACCAATCTCGCGAACCCTAAAGCGATTATCTACTTTGGTT
CGGTGTTCTCGCTGTTTGTCGGTGATAATGTCGGCACCACCGAACGCTGGGGCATTTTCGCGTTGATTATTGTCGAAACA
CTGGCGTGGTTTACCGTCGTTGCCAGCCTGTTTGCTCTGCCGCAAATGCGCCGTGGTTATCAACGTCTGGCGAAGTGGAT
TGATGGTTTTGCCGGGGCGTTATTTGCCGGATTTGGCATTCATTTGATTATTTCGCGTTAA

Upstream 100 bases:

>100_bases
GATTCGTGCGCATGTCGATGGTGACGACGAAGAGTAGTCAGCAGCATAAAAAAGTGCCAGGATGAAGACTCCGTAAACGT
TTCCCCCGCGAGTCTAATGT

Downstream 100 bases:

>100_bases
TGCCAGACGCGTCATCAGAGTAAGTCGGATAAGGCGTTTACGCCGCATCCGACATTATTTTCACGCATGCCTCGCCGATG
CTAACAGCGCTCCCACCAGC

Product: threonine efflux system

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGL
YLCWMGYQMLRGALKKEVVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVET
LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR

Sequences:

>Translated_206_residues
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGL
YLCWMGYQMLRGALKKEVVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVET
LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR
>Mature_206_residues
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGL
YLCWMGYQMLRGALKKEVVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVET
LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=99.0291262135922, Blast_Score=409, Evalue=1e-116,
Organism=Escherichia coli, GI1786522, Length=200, Percent_Identity=28, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788099, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22561; Mature: 22561

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEVVSAPAPQVELAKSGRSFLKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVETLAWFTVVASLFALPQMRRGY
HHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLAKWIDGFAGALFAGFGIHLIISR
HHHHHHHHHHHHHHHHHHHHHEEEEC
>Mature Secondary Structure
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEVVSAPAPQVELAKSGRSFLKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVETLAWFTVVASLFALPQMRRGY
HHCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLAKWIDGFAGALFAGFGIHLIISR
HHHHHHHHHHHHHHHHHHHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]